Abstract：
:We have studied the cholinergic nerve fibers (CNF) of human uveoscleral tissue in normal and pathological conditions (intraocular pressure: (IOP) of various degrees ) and have performed a quantitative image analysis of CNF with the aim of studying an hypothetical association between IOP and the uveoscleral level of cholinergic neurotransmitter in nerve fiber of the enucleated human eyes. Eleven patients, previously enrolled in our medical protocols are affected by an increase of IOP of various degrees, were subjected to surgical enucleation of one eyeball for traumatic or neoplastic reasons and were the donors of samples of the uveoscleral tissue for CNF demonstration. The samples were also submitted to quantitative image analysis. An enzymatic activity, Acetylcholinesterase (AChe), is present in nerve fibers that innervate the human uveoscleral tissue. The AChe-positive nerve fibers represent about 7.2% of the observed area in normal conditions, while in patients with elevated IOP AChe activity is about 20.3% of the total observed area. The increase of AChe activity in our experiments, all performed under the same conditions, and therefore, with comparable results, may be related with the increase of IOP.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Cavallotti C,Pescosolido N,Leali FM,Gherardi F,Cavallotti Ddoi
10.1023/a:1006306812296subject
Has Abstractpub_date
1998-01-01 00:00:00pages
349-53issue
6eissn
0165-5701issn
1573-2630journal_volume
22pub_type
杂志文章abstract：:The objective of this study is to evaluate the visual prognosis and postoperative course in advanced glaucoma patients who underwent trabeculectomy. The records of 30 patients with advanced visual field (VF) defects undergoing trabeculectomy were retrospectively reviewed. Severe VF defects were defined as those with a...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9494-0
更新日期：2011-12-01 00:00:00
abstract：:One hundred cases of clinically acceptable sympathetic ophthalmia (SO) were evaluated histologically to determine the incidence of atypical features and correlate them with the severity of choroidal inflammation. The inflammatory response in the choroid varied from a focal non-granulomatous to a diffuse non-necrotizin...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00161902
更新日期：1982-02-01 00:00:00
abstract：PURPOSE:To evaluate the effects of epiretinal membrane (ERM) formation on the anatomic and functional results of subjects with diabetic macular edema (DME) who are receiving intravitreal aflibercept injections (IAIs). MATERIALS AND METHODS:This retrospective comparative study includes 29 eyes with DME (Group 1) and 43...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01444-y
更新日期：2020-10-01 00:00:00
abstract：:We report a case of peripheral ulcerative keratitis associated with neutrophilic dermatosis of the dorsal hand, a recently described clinical entity. A 68-year-old man presented with concurrent peripheral ulcerative keratitis of the right eye and neutrophilic dermatosis of the dorsal hand causing pustular skin eruptio...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9428-x
更新日期：2011-04-01 00:00:00
abstract：:We constructed a contact lens with an integrated pressure-sensing device. It is housed in a container with three force-sensing elements, each 120 degrees apart, enabling measurement of the appositional force, i.e., the force with which the instrument is held against the eye. In part 1 of the study, the lens' precision...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006292102204
更新日期：1998-01-01 00:00:00
abstract：PURPOSE:Coagulase-negative staphylococci have been reported to be the most frequent cause of bacterial postoperative endophthalmitis. Biofilm formation is the major virulence factor of Staphylococcus epidermidis and is often associated with methicillin resistance. This study aims at evaluating the presence of biofilm-p...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0339-8
更新日期：2017-08-01 00:00:00
abstract：:Using a direct immunofluorescent technique and monoclonal antibody, chlamydia trachomatis was detected in the conjunctival smears of 13 out of 47 patients presenting with conjunctivitis or keratoconjunctivitis (an incidence of 28%). Two patients presented with acute symptoms of few days duration, whereas the condition...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133933
更新日期：1988-01-01 00:00:00
abstract：:Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already inf...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136735
更新日期：1987-12-01 00:00:00
abstract：PURPOSE:Extemporaneously prepared miconazole eye drops (EPMD) are used by some eye care practitioners to manage keratomycosis in Ghana. This study therefore aimed to determine the efficacy and safety of EPMD using in vitro and in vivo experimental models. METHODS:The minimum inhibitory concentration (MIC) of EPMD was ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0707-z
更新日期：2018-10-01 00:00:00
abstract：:The purpose of this study was to report on the occurrence and management of posterior synechiae (PS) in three hyperopic eyes after iris-fixated anterior chamber phakic IOL implantation. This is a case report of a 55-year-old man and a 55-year-old lady who had undergone iris-fixated anterior chamber phakic IOL implanta...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0202-y
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:Early predictors of diabetic complications may aid in the prevention and/or management of these complications. The aim of this cross-sectional study was to determine the predictive value of retinopathy for the presence of other diabetic complications. METHODS:The population studied comprised 648 patients with ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014409829614
更新日期：2001-01-01 00:00:00
abstract：:The purpose of this study was to determine the penetration of itraconazole, a type of azole antifungal agent, into the aqueous humor and vitreous after repeated oral administrations. Fungal endophthalmitis developed bilaterally in a 21-year-old man who had a history of intravenous hyperalimentation following abdominal...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9696-0
更新日期：2013-10-01 00:00:00
abstract：INTRODUCTION:Uveitis encompasses a wide variety of sight-threatening diseases characterized by intraocular inflammation. It is often classified as infectious and non-infectious uveitis. Unlike infectious uveitis, a distinct infectious agent cannot be identified in non-infectious uveitis and disease origin is usually au...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0984-1
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To explore whether retrobulbar administration of nerve growth factor (NGF) can restore visual function of streptozotocin-induced diabetes rats. METHODS:A high-sucrose/high-fat diet and single injection of streptozotocin (STZ) were used in modeling diabetes. During week 13-15 after STZ injection, diabetic rats ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01537-8
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Aromatase inhibitors (anastrozole, letrozole) and selective estrogen receptor modulators (tamoxifen) are widely used as adjuvant hormonal therapy in women with hormone receptor-positive breast cancer. We aimed to evaluate the effects of oral adjuvant hormonotherapy on tear functions in patients with breast canc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01384-7
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:To report a large, consecutive series of endophthalmitis of all causes managed at a tertiary referral retina center. METHODS:Retrospective chart review of all cases diagnosed with endophthalmitis that received reatment and follow-up between January 2000 and January 2005. RESULTS:A total of 67 patients were di...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9068-3
更新日期：2007-08-01 00:00:00
abstract：PURPOSE:To compare the efficacy of intravitreal injection of ranibizumab, dexamethasone implant and aflibercept for the management of macular edema (ME) related to branch retinal vein occlusion (BRVO). METHODS:This retrospective and comparative study included 62 eyes of 62 patients with BRVO and ME. Patients received ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0618-z
更新日期：2018-08-01 00:00:00
abstract：:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00149150
更新日期：1982-11-01 00:00:00
abstract：:Retinal astrocytic hamartomas are benign tumors of the retinal nerve fiber layer (NFL) that may be found in association with tuberous sclerosis (TS). We describe the spectral-domain optical coherence tomography (SD-OCT) features of type 1 astrocytic hamartomas in a child with TS that may aid in the diagnosis and follo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9586-5
更新日期：2012-10-01 00:00:00
abstract：PURPOSE:To analyze the relationship between the seasonal allergic conjunctivitis (SAC), eotaxin-2, matrix metalloproteinase-9 (MMP-9), and the topographical findings in the keratoconus patients. METHODS:Thirty-four eyes of patients without SAC (Group 1), 34 eyes of patients with SAC (Group 2), and 20 eyes of control s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01149-x
更新日期：2020-01-01 00:00:00
abstract：:This retrospective study reviews the clinical and histopathological features of ocular epidermoid cyst. The 30-year laboratory records of all the patients of the Igbo ethnic group, whose surgical specimens were received at a central pathology laboratory service in south-eastern Nigeria, West Africa, were reviewed. The...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1025483024858
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-017-0685-1
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To assess safety and efficacy of deep topical anesthesia with ropivacaine-soaked sponge compared with topical anesthesia with oxybuprocaine in patients undergoing phacoemulsification. METHODS:This was a retrospective study where records of patients operated for cataract were evaluated. Patients using a visual ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01132-6
更新日期：2019-12-01 00:00:00
abstract：:From January 1990 until October 1992, 103 Zimbabwean patients underwent intracapsular cataract extraction by a general medical doctor. Of the first 100 patients operated upon, 50 were traced of which 37 could be assessed adequately. Operative complications and visual acuities after three months show that this is an ef...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00131924
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:A population-based study was conducted to determine the prevalence of color deficiencies in secondary-school students (ages 12-14) in Tehran. METHODS:A total of 2,058 students (1,136 males, 922 females) were examined with Ishihara pseudoisochromatic color plates. RESULTS:In the study population, 97 cases of d...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00175263
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To perform vector analysis of changes in corneal astigmatism and evaluate changes in corneal topographic parameters following the lateral tarsal strip (LTS) procedure in patients with involutional ectropion or entropion. METHODS:Nineteen eyes of 15 patients (10 eyes with ectropion and 9 eyes with entropion) we...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0987-y
更新日期：2019-08-01 00:00:00
abstract：:Fifty patients who developed preretinal or papillary neovascularization following tributary vein occlusion were treated by laser photocoagulation. Areas of non-perfused retina within the distribution of the obstructed vein were identified by fluorescein angiography and ablated using moderately intense laser photocoagu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130697
更新日期：1981-05-01 00:00:00
abstract：:Aqueous flare and cells are the two inflammatory parameters of anterior chamber inflammation resulting from disruption of the blood-ocular barriers. When examined with the slit lamp, measurement of intraocular inflammation remains subjective with considerable intra- and interobserver variations. Laser flare cell photo...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-009-9310-2
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To present the long-term results of therapeutic keratoplasty for microbial keratitis in moderate to advanced phases. METHODS:The medical records of 44 patients who underwent therapeutic keratoplasty for microbial keratitis at the ophthalmology clinic of a training and research hospital between June 2012 and Ma...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01538-7
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Ibopamine is used when performing provocative tests, thanks to its pharmacological property of increasing ocular pressure in eyes with outflow system impairment. This study summarizes the latest results that we have achieved with reference to its clinical-diagnostic use. METHODS:175 (250 eyes) POAG patients, 1...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00212962
更新日期：1996-01-01 00:00:00
