Abstract：
PURPOSE:To report a large, consecutive series of endophthalmitis of all causes managed at a tertiary referral retina center. METHODS:Retrospective chart review of all cases diagnosed with endophthalmitis that received reatment and follow-up between January 2000 and January 2005. RESULTS:A total of 67 patients were diagnosed with endophthalmitis. The most common cause was postoperative endopthalmitis after cataract surgery. Initial management was vitreous needle biopsy with intravitreal antimicrobial injection in a majority of cases (79%). Vitreous cultures were positive in 32 eyes (44.4%); the most common isolate was coagulase negative Staphylococci. Final visual acuity was improved in 61% of patients. More than a third (38%) had vision worse than count fingers. Twenty-eight eyes (39%) needed pars plana vitrectomy for secondary complications as a consequence of endophthalmitis. CONCLUSIONS:Cataract surgery remains the most common cause of endophthalmitis in this large tertiary referral retina center. Endophthalmitis resolved with vitreous needle biopsy and intravitreal injections in more than half of the cases. However, more than a third of patients required additional vitreoretinal surgery for secondary complications. More than a third of patients had nonfunctional vision after the resolution of endophthalmitis, which highlights the severity of this condition in the current expanding era of office-based intravitreal pharmacotherapy for retinal diseases.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Karacal H,Kymes SM,Apte RSdoi
10.1007/s10792-007-9068-3subject
Has Abstractpub_date
2007-08-01 00:00:00pages
251-9issue
4eissn
0165-5701issn
1573-2630journal_volume
27pub_type
杂志文章abstract：BACKGROUND:To evaluate the retinal nerve fiber layer (RNFL) and peripapillary vascular density (VD) changes in the pediatric group with optic disk drusen (ODD). METHODS:Sixty eyes of 30 patients with buried ODD referred by the pediatric or neurology physicians to ophthalmology clinic with a preliminary diagnosis of pa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-021-01700-9
更新日期：2021-01-18 00:00:00
abstract：PURPOSE:To evaluate and compare outcomes of CO2 laser-assisted sclerectomy surgery (CLASS) with mitomycin C (MMC) combined with or without phacoemulsification in adult Asian glaucoma patients. DESIGN:Retrospective, comparative study. METHODS:Adult Asian glaucoma patients who underwent CLASS alone or combined with pha...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-021-01707-2
更新日期：2021-01-22 00:00:00
abstract：:We made two trips to Cuba, as part of an invited international delegation, to investigate an epidemic of optic neuropathy-induced blindness. We worked closely with Cuban scientists and clinicians in their efforts to understand and then deal with 50,000 cases of blindness and an entire population at risk. This gave an ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00930318
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:Corneal melting with perforation is a severe ophthalmic complication of autoimmune disorders such as rheumatoid arthritis. It requires urgent medical management in order to maintain the integrity of the globe and preserve vision. Treating this complication by penetrating keratoplasty is problematic due to the h...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0545-z
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To identify risk factors for endogenous endophthalmitis (EE) in hospitalized adults, under 65 years of age, with a history of intravenous opioid use and non-ocular infection. METHODS:The National Inpatient Sample Database was used to identify cases of EE with a recent history of intravenous opioid use disorder...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-021-01709-0
更新日期：2021-01-27 00:00:00
abstract：PURPOSE:This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy. METHODS:Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations ...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-017-0685-1
更新日期：2018-10-01 00:00:00
abstract：UNLABELLED:We examined the immunocytochemical features of after cataract tissue and cataractous lens epithelium prior to cataract surgery and at the time of surgery. METHODS:This study included 23 cases. Antibodies against the following antigens were used: epidermal growth factor (EGF), EGF receptor (EGF-R), fibroblas...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1010640118852
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model. METHODS:A chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.1%, Met_0.5%, sham...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0922-2
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To investigate the risk factors associated with corneal epithelial defects (CED) and delayed healing (exceeding 1 week) following pars plana vitrectomy (PPV). METHODS:This retrospective study enrolled patients who underwent PPV at a single center in Taiwan between 2011 and 2012. Medical records were reviewed, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0429-7
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Ibopamine is used when performing provocative tests, thanks to its pharmacological property of increasing ocular pressure in eyes with outflow system impairment. This study summarizes the latest results that we have achieved with reference to its clinical-diagnostic use. METHODS:175 (250 eyes) POAG patients, 1...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00212962
更新日期：1996-01-01 00:00:00
abstract：:This retrospective study reviews the clinical and histopathological features of ocular epidermoid cyst. The 30-year laboratory records of all the patients of the Igbo ethnic group, whose surgical specimens were received at a central pathology laboratory service in south-eastern Nigeria, West Africa, were reviewed. The...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1025483024858
更新日期：2001-01-01 00:00:00
abstract：:To evaluate the role of brimonidine (BMD), an alpha-2 agonist, in the management of clinically significant macular edema (CSME) in diabetic maculopathy with ischemic changes. A prospective, randomized controlled trial including 30 eyes of 30 metabolically stable diabetic patients with CSME showing fundus fluorescein a...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-013-9871-y
更新日期：2014-08-01 00:00:00
abstract：:Suprachoroidal hemorrhages were created in 15 albino rabbit eyes by injecting 0.1 cc of autologous blood into the suprachoroidal space. One day later, 10 of these eyes were treated with intravenous tissue plasminogen activator (TPA). Doses of 1 mg per kg were given to each rabbit over 2 to 3 hours by intravenous infus...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159862
更新日期：1990-07-01 00:00:00
abstract：:In a randomized, double-masked, single drop study the effect of topical isosorbid-mononitrate (ISMO) 0.5% eye drops, the main metabolite of isosorbid-dinitrate, widely used in the treatment of coronary heart diseases, was studied in patients suffering from open angle glaucoma or ocular hypertension. There was no stati...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00171028
更新日期：1991-07-01 00:00:00
abstract：:Retinal arteriovenous malformations are rare and most are reported to be asymptomatic. We report an 11-year-old boy who attended for blunt trauma to his eye. The first ophthalmologic examination was performed in Nikookari Hospital Eye Emergency Room. Visual acuity was 20/20 and relative afferent pupillary defect was n...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9636-z
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To perform vector analysis of changes in corneal astigmatism and evaluate changes in corneal topographic parameters following the lateral tarsal strip (LTS) procedure in patients with involutional ectropion or entropion. METHODS:Nineteen eyes of 15 patients (10 eyes with ectropion and 9 eyes with entropion) we...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0987-y
更新日期：2019-08-01 00:00:00
abstract：:This study aimed to present precancerous and cancerous epithelial eyelid lesions, their histopathological features, and possible correlations with clinical parameters. The retrospective study included 147 formalin-fixed, paraffin-embedded samples. We studied precancerous and cancerous epithelial eyelid lesions. Preneo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0258-8
更新日期：2017-02-01 00:00:00
abstract：:Bietti crystalline corneoretinal dystrophy (BCD, MIM 210370) is a type of hereditary retinal disorder which commonly occurs in China. It is known that mutations in the CYP4V2 gene result in BCD. The purpose of this study was to investigate the case of a Chinese family and characterize the polymorphisms of the CYP4V2 g...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9686-2
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:Proliferative vitreoretinopathy (PVR) is characterized by the formation of cellular membranes on the detached retina and also in the vitreous. Glial cells can be found in epiretinal and subretinal membranes from eyes with PVR, proliferative diabetic retinopathy (PDR), idiopathic macular pucker, uveitis and othe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1022509614815
更新日期：2001-01-01 00:00:00
abstract：:Transvitreal pars plana sclerotomy using the contact Nd:YAG laser with a sapphire probe was performed on a group of rabbit eyes and compared with a similar procedure performed with a Ziegler knife. Although the intraocular pressure (IOP) was lowered in both groups of animals, the reduction was greater and more lasting...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130620
更新日期：1988-01-01 00:00:00
abstract：:The cone dystrophies can be subdivided into 3 functional stages: central cone disease, peripheral cone disease and diffuse cone disease, respectively. In the patient material of our clinic the sex distribution of patients presenting with te diffuse cone disease stage was abnormal: 22 males and 3 females. The authors s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00155631
更新日期：1987-08-01 00:00:00
abstract：:We report a case of choroidal melanoma with features suggestive of orbital cellulitis. A 24-year-old Asian Indian male presented with a 20-day history of sudden loss of vision in the right eye. Edematous eyelids with complete mechanical ptosis, complete ophthalmoplegia, gross proptosis accompanied by massive chemosis,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9836-1
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:To investigate the feasibility of intrastromal lenticule insertion to restore corneal shape in a model of ectatic human cornea. METHODS:For this experimental ex vivo study on 34 human corneas unsuitable for transplantation, 17 corneas were thinned by decentralized posterior excimer laser ablation to 200 μm thi...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-019-01106-8
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:We evaluated the ability of optic disc parameters and nerve fiber analysis with the Glaucoma-scope to distinguish glaucoma from normal or hypertensive eyes. METHODS:Glaucoma-scope examination was performed on 68 eyes of 44 patients split into following groups based on Humphrey 24-2 visual field and clinical cr...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00212942
更新日期：1996-01-01 00:00:00
abstract：:The purpose of this study is to evaluate whole lysyl oxidase like 1 (LOXL1) gene by sequence analysis in Turkish patients with exfoliation glaucoma (XFG). A total of 48 (35 male, 13 female) patients with XFG were enrolled. Besides routine ophthalmological examination, peripapillary retinal nerve fibre layer (RNFL) ana...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0174-y
更新日期：2016-10-01 00:00:00
abstract：:In a study of 95 patients with intraocular foreign body injuries presenting in the eight year period from 1978-1986 we found the overall visual results to be good with 62% of patients achieving a final visual acuity of 6/18 or better. The factors leading to a poor visual result were a large intraocular foreign body, p...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00137136
更新日期：1988-01-01 00:00:00
abstract：:A national study was conducted in children attending six schools for the blind in Malaysia to identify the anatomical site and underlying causes of blindness (BL) and severe visual impairment (SVI), with a view to determine the potentially preventable and treatable causes so that appropriate control measures can be im...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014493228691
更新日期：2001-01-01 00:00:00
abstract：:To describe the efficacy of intravitreal chemotherapy (IViC) preceded by intra-arterial chemotherapy (IAC) for the treatment of advanced stage retinoblastoma. This non-comparative interventional case series retrospectively reviewed the medical records of six patients who presented within months of each other with unil...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0129-8
更新日期：2015-12-01 00:00:00
abstract：:The main visual field indices of Flammer and the analogous ones of Heijl have been compared based on a population of 113 glaucomatous visual fields. It is shown that for the population studied, the differences between the two sets of indices are negligible for Octopus G1 program results and that they may thus be used ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128955
更新日期：1991-09-01 00:00:00
abstract：:To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based perito...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9840-5
更新日期：2014-06-01 00:00:00
