Abstract：
:Invasive aspergillosis is a rare disease and is often misdiagnosed. The clinical course is quite aggressive and it is a potentially fatal disease. We report a case of invasive aspergillosis involving the dura mater and optic nerves which was successfully treated with voriconazole, even though the patient had residual monocular blindness. An 86-year-old Japanese man complained of developing loss of vision in his left eye while taking oral fluconazole prescribed by an otolaryngologist for mycosis of the left maxillary sinus. He was referred to our hospital. At the first visit, he already had no light perception in the left eye, with decreased ocular motility in all directions and orbital apex syndrome. His corrected distance visual acuity (CDVA) in the right eye was 20/25 with enlargement of Mariotte's blind spot. Magnetic resonance imaging revealed inflammation around both optic nerves that also involved the dura mater. His antifungal therapy was changed to intravenous voriconazole. Although his right CDVA temporarily declined to 20/50, it improved to 20/16 by 10 months after the initiation of treatment. Maxillary sinus biopsy detected Aspergillus. Invasive aspergillosis progresses rapidly and aggressively. The present case highlights the importance of early diagnosis and selection of an appropriate antifungal agent.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Arakawa H,Suto C,Notani H,Ishida T,Abe K,Ookubo Ydoi
10.1007/s10792-013-9730-xsubject
Has Abstractpub_date
2014-02-01 00:00:00pages
85-9issue
1eissn
0165-5701issn
1573-2630journal_volume
34pub_type
杂志文章abstract：PURPOSE:A population-based study was conducted to determine the prevalence of color deficiencies in secondary-school students (ages 12-14) in Tehran. METHODS:A total of 2,058 students (1,136 males, 922 females) were examined with Ishihara pseudoisochromatic color plates. RESULTS:In the study population, 97 cases of d...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00175263
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:To determine the inflammatory course and level of visual rehabilitation after cataract extraction and posterior chamber lens implantation in patients with Fuchs' heterochromic iridocyclitis complicated by cataract. METHODS:In a clinical trial, 32 eyes (visual acuity of 20/160 or worse) of 30 patients underw...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1023/a:1026490902566
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To evaluate the long-term safety and efficacy of Mycophenolate Mofetil (MMF) for the control of cystoid macular oedema (CMO) secondary to noninfectious uveitis (NU). METHODS:The medical records of 19 consecutive patients with inflammatory CMO treated with MMF were retrospectively reviewed. Patient demographics...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9200-z
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:Retinal vascular abnormalities are associated with choroidal melanoma. Although tumor ischemia, resulting in soluble angiogenic factor production, is a proposed etiology of these abnormalities, other sources of ischemia may also contribute. Mushroom-shaped choroidal melanomas have increased loss of the overlyin...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1021170402679
更新日期：2001-01-01 00:00:00
abstract：:We report on two cases of bilateral chorioretinal colobomas with ocular anomalies in patients with CHARGE syndrome. In the first case, a female infant was born at 36 + 5 weeks gestation. At birth, the patient demonstrated a small left eye. Slit-lamp examination revealed colobomas of both irises. Fundus examination sho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9817-4
更新日期：2014-06-01 00:00:00
abstract：:To describe the efficacy of intravitreal chemotherapy (IViC) preceded by intra-arterial chemotherapy (IAC) for the treatment of advanced stage retinoblastoma. This non-comparative interventional case series retrospectively reviewed the medical records of six patients who presented within months of each other with unil...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0129-8
更新日期：2015-12-01 00:00:00
abstract：:The purpose of the study is to determine the incidence and distribution of paravascular lamellar holes (PLH) around retinal vessels in highly myopic eyes and their relationship with macular retinoschisis (MR). We examined 306 eyes of 178 patients with high myopia, performing multiple scans of the posterior pole within...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0110-6
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:To evaluate the preliminary effects of treating the half of high latent hyperopia on refractive and visual outcomes of femtosecond laser-assisted in situ keratomileusis (LASIK) in young subjects with hyperopia. METHODS:This non-randomized comparative study includes 120 eyes of 60 subjects who underwent femt...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01421-5
更新日期：2020-09-01 00:00:00
abstract：:The ocular surface is exposed to many chronic inflammatory stimuli, and goblet cell hyperplasia of the conjunctiva occurs in many situations. We report two cases of epithelial goblet cell hyperplasia with nonspecific chronic inflammation which occurred on the internal canthus of elderly people. These cases shared the ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-015-0083-5
更新日期：2015-08-01 00:00:00
abstract：AIM:To evaluate the whether intravitreal erythropoietin (EPO) administration has any beneficial or adverse effect in patients with late-stage optic neuropathy (ON) or not. METHODS:The study examined 16 eyes of 16 patients who had late-stage ON and ≥1/20 best-corrected visual acuity (BCVA) in their affected eye. There ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0553-z
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate the accuracy of the convolutional neural network (CNN) model in glaucoma identification with three primary colors (red, green, blue; RGB) and split color channels using fundus photographs with a small sample size. METHODS:The dataset was prepared using color fundus pho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01485-3
更新日期：2020-11-01 00:00:00
abstract：:Management of retinoblastoma (Rb), the most common intraocular malignant tumor in childhood, is tailored to each individual case and based on the overall situation. We present a case of bilateral Rbs in a 4-month-old girl, referred to our center for bilateral leukocoria. In the right eye, the optic disc was partially ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9703-5
更新日期：2013-10-01 00:00:00
abstract：:A case of keratomycosis caused by Alternaria species in a patient with glaucoma is reported. A 55-year-old Japanese man who had been followed for developmental glaucoma presented with corneal ulcer in his right eye, which did not respond to antibacterial agents. There was no history of traumatic episode. Culture on po...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9260-0
更新日期：2009-12-01 00:00:00
abstract：:The purpose of this study was to report various conditions masquerading as congenital nasolacrimal duct obstruction (CNLDO). Retrospective review was designed in a tertiary hospital setting. 92 eyes of 65 consecutive patients were included in this study. All patients presenting with CNLDO symptomatology but where the ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0050-1
更新日期：2015-12-01 00:00:00
abstract：:Onchocerciasis is a major blinding disease affecting at least 28 million people in Africa and Latin America. Although a large-scale vector control program has been highly successful in limiting transmission of infection in West Africa, there has not been a satisfactory form of treatment available for those already inf...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136735
更新日期：1987-12-01 00:00:00
abstract：OBJECTIVES:To determine the common eye diseases as well as the prevalence and causes of blindness and visual impairment in young adult residents of rural areas of Anambra State, Nigeria. MATERIALS AND METHODS:Three rural villages in Anambra State, Nigeria were selected by simple random sampling. A structured questionn...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006338013075
更新日期：1998-01-01 00:00:00
abstract：:Pigmented rabbits were treated with timolol maleate, betaxolol hydrochloride or levobunolol hydrochloride eye drops twice a day for six months. Animals of the same age group and breed were used as controls. There were no differences observed in corneal epithelium with light and transmission electron microscopy. With s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028643
更新日期：1989-01-01 00:00:00
abstract：:We report our experience with three cases of Epstein-Barr virus (EBV)-associated uveitis. These patients had the following common clinical features: 1) a common cold-like prodrome, 2) bilateral involvement, 3) severe acute anterior uveitis with fibrinous exudate, 4) granulomatous anterior uveitis in the chronic stage,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163559
更新日期：1990-10-01 00:00:00
abstract：:Postural behaviour of intraocular pressure (IOP) was studied in 29 glaucomatous eyes before and after argon laser trabeculoplasty (ALT) and compared with that of 60 normal eyes. Although argon laser trabeculoplasty was successful in lowering the IOP below 21 mm Hg, it produced little effect on the postural behaviour o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00916436
更新日期：1992-05-01 00:00:00
abstract：:In a prospective study of untreated ocular hypertension 117 eyes were non-exfoliative and 20 eyes exfoliative. The percentage of optic disc pallor was significantly larger in the exfoliative than in the non-exfoliative group, whereas no significant differences were found in IOP or in the visual field. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028632
更新日期：1989-01-01 00:00:00
abstract：:To report the clinical and microbiological characteristics of infectious endophthalmitis after Boston type I keratoprosthesis (B-K-Pro) implantation. Retrospective analysis of 136 eyes that received a B-K-Pro type 1 between 1999 and 2012 was performed. Five eyes with a diagnosis of exogenous endophthalmitis after B-K-...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9994-9
更新日期：2015-10-01 00:00:00
abstract：:This study reports the outcomes of therapeutic penetrating keratoplasties, defined as keratoplasties performed to eradicate active infectious corneal diseases or to repair a structural defect of the cornea. The records of 24 eyes of 24 patients (17 female and 7 male) treated with therapeutic penetrating keratoplasty b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9931-y
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:To compare the efficacy and safety of two intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents, ranibizumab and aflibercept, for the treatment of vascularized pigment epithelium detachment (vPED) due to age-related macular degeneration (AMD) in a follow-up time of 12 months. METHODS:Particip...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0833-2
更新日期：2019-02-01 00:00:00
abstract：:The authors reviewed their experience with 429 cases of orbital exenteration between 1963 and 1993. Apart from the 22 cases operated in concert with other physicians, 407 cases were operated by an ophthalmologist and spontaneous granulation technique was used. Total or eyelid-sacrificing exenteration was carried out f...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133735
更新日期：1995-01-01 00:00:00
abstract：:The Acuityscope projects an image of a three bar resolution test target onto the patient's retina, where it is viewed and read by an observer. The test target consists of a series of three bar targets varying in size on a logarithmic scale. Individual targets are identified in the projected image by Bailey-Lovie log v...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00224470
更新日期：1991-03-01 00:00:00
abstract：:In a randomized, double-masked, single drop study the effect of topical isosorbid-mononitrate (ISMO) 0.5% eye drops, the main metabolite of isosorbid-dinitrate, widely used in the treatment of coronary heart diseases, was studied in patients suffering from open angle glaucoma or ocular hypertension. There was no stati...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00171028
更新日期：1991-07-01 00:00:00
abstract：:The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00127638
更新日期：1983-02-01 00:00:00
abstract：OBJECTIVES:To compare the intraocular pressure (IOP)-lowering effects of ripasudil, a rho-kinase inhibitor, and selective laser trabeculoplasty (SLT) as adjuvant therapy in Japanese glaucoma patients and to identify the factors associated with treatment success. METHODS:We performed a retrospective medical chart revie...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01615-x
更新日期：2020-10-20 00:00:00
abstract：PURPOSE:To report the first European case of endogenous endophthalmitis secondary to a liver abscess due to Klebsiella pneumoniae expressing MagA gene. METHODS:A 33-year-old diabetic patient was admitted for fever and right upper quadrant abdominal pain. Abdominal computed tomography and laboratory studies were perfor...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9111-4
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:To evaluate the safety indexes and efficacy of Artisan phakic intraocular lens (IOL) for the correction of high myopia. METHODS:Retrospective interventional case series reports. Thirty-one eyes (22 patients) with myopia from -5.25 to -19.00 diopters underwent implantation of an Artisan phakic IOL. Follow-up...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-005-5016-2
更新日期：2004-07-01 00:00:00
