Abstract:
PURPOSE:To investigate the natural course, visual outcome, and risk factors for visual loss after nonarteritic anterior ischemic optic neuropathy (NAION) attack in Chinese patients from a tertiary medical center in Southern Taiwan. METHODS:This is a longitudinal observational study that included sixty NAION patients, who were seen in our neuro-ophthalmology clinic from 2007 to 2016. Records of their ophthalmic history, medical history, best-corrected visual acuity (BCVA), visual field (VF) testing, and optical coherence tomography (OCT) were obtained for analysis. RESULTS:When the first visit was within two weeks after NAION onset, 62% of patients had BCVA of less than 0.1 (logMAR BCVA ≥ 1) and 38% had at least moderate-severe depression (VF grade ≥ 3) on VF on the initial visit. VA stabilized at three months after onset and was predictive of VA at 12 months. Diabetes mellitus was a risk factor associated with VA worsening. Sixty-one percent of patients had BCVA of less than 0.1 at 12 months after onset. VF remained relatively unchanged during the disease, with 41% eyes having VF grade ≥ 3 at 12 months after onset. On OCT, all quadrants of retinal nerve fiber layer thickened initially, returned to the level of the fellow eye at one month, and continued thinning up to 12 months slowly. CONCLUSION:In Southern Taiwan, a higher proportion of Chinese patients (over half) presented with severe visual loss during the first two weeks of NAION attack and at 12 months after the onset of NAION as compared to the findings previously reported in Caucasians. Understanding the natural course of NAION in Chinese patients may provide insights toward a possible therapeutic window for NAION treatments in this group of patients.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Huang HM,Wu PC,Kuo HK,Chen YJ,Poon LYdoi
10.1007/s10792-020-01448-8subject
Has Abstractpub_date
2020-10-01 00:00:00pages
2667-2676issue
10eissn
0165-5701issn
1573-2630pii
10.1007/s10792-020-01448-8journal_volume
40pub_type
杂志文章abstract:PURPOSE:To assess posterior inflammation using a fluorescein (FA)/indocyanine-green angiography (ICGA) scoring system, and compare them to the presently recommended outcome measure, the standardization of uveitis nomenclature vitreous haze score (SUN-VH) in stromal choroiditis. METHODS:This was a retrospective study o...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0979-y
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01521-2
更新日期:2020-12-01 00:00:00
abstract::Early-onset sarcoidosis (EOS) and Blau syndrome are rare auto-inflammatory diseases characterized by a triad of skin rash, granulomatous uveitis, and symmetrical polyarthritis occurring in early childhood. In this paper, we describe a case report very interesting for the multidisciplinary management (pediatric rheumat...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-015-0135-x
更新日期:2016-02-01 00:00:00
abstract::Retinal arteriovenous malformations are rare and most are reported to be asymptomatic. We report an 11-year-old boy who attended for blunt trauma to his eye. The first ophthalmologic examination was performed in Nikookari Hospital Eye Emergency Room. Visual acuity was 20/20 and relative afferent pupillary defect was n...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9636-z
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To identify risk factors for endogenous endophthalmitis (EE) in hospitalized adults, under 65 years of age, with a history of intravenous opioid use and non-ocular infection. METHODS:The National Inpatient Sample Database was used to identify cases of EE with a recent history of intravenous opioid use disorder...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-021-01709-0
更新日期:2021-01-27 00:00:00
abstract::Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon disease most frequently occurring in the head and neck region. It occurs in all races. In spite of a clear distinction between ALHE and Kimura's disease on histological grounds for almost 20 years now, confusion and misdiagnosis still exist to date. Thr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9741-7
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:To describe and analyze short-term posterior vitreous abnormalities following intravitreal ocriplasmin in eyes with symptomatic vitreomacular traction syndrome (VMT). METHODS:In this institutional, prospective and interventional study enrolled patients with symptomatic focal VMT syndrome treated with intravitr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-019-01177-7
更新日期:2020-01-01 00:00:00
abstract::To evaluate the clinical efficacy of transcutaneous everting sutures for lower eyelid involutional entropion in Chinese patients. A retrospective, non-comparative, interventional case series. This retrospective study consecutively reviewed the medical records of all patients with involutional lower eyelid entropion wh...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9893-5
更新日期:2014-08-01 00:00:00
abstract::The traditional opinion that increased intraocular pressure is the cause of glaucoma is controversial, probably mainly because of the fact that firm evidence for the value of pressure reduction is largely lacking. The present article reviews results from short term studies of visual fields before and after pressure re...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02028651
更新日期:1989-01-01 00:00:00
abstract::To analyze the association between Eales disease, histocompatibility leukocyte antigen alleles (HLA-A/B, HLA-DRB/DQB) and tuberculosis infection, and to explore susceptible genes and protective genes associated with Eales disease and tuberculosis infection in a population of Han nationals from Zunyi City in Guizhou Pr...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9718-6
更新日期:2013-10-01 00:00:00
abstract::This study aimed to monitor the graft-host junction's (GHJ's) apposition with anterior segment optical coherence tomogram after penetrating keratoplasty (PK) and correlate the analysis with the preoperative diagnosis. Fifty-one eyes of 50 patients with various preoperative diagnosis of adherent leucoma, pseudophakic b...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0269-5
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:To evaluate the long-term safety and efficacy of Mycophenolate Mofetil (MMF) for the control of cystoid macular oedema (CMO) secondary to noninfectious uveitis (NU). METHODS:The medical records of 19 consecutive patients with inflammatory CMO treated with MMF were retrospectively reviewed. Patient demographics...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9200-z
更新日期:2009-06-01 00:00:00
abstract::We encountered two cases of Harada's disease in monozygotic twins, and this is the first such report as far as could be determined. Case 1 was a 32-year-old woman who presented a typical clinical picture of Harada's disease. Seven years later, case 2 (the younger sister), also presented with the disease at 39 years of...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00917073
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Few case reports have described vaso-occlusive retinopathy in systemic lupus erythematosus (SLE) using optical coherence tomography (OCT) angiography. Here we report the clinical features of a patient with SLE, complicated by Kikuchi-Fujimoto disease, who developed vaso-occlusive retinopathy. We then describe t...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0650-z
更新日期:2018-08-01 00:00:00
abstract::The choroidal vascular bed has many interesting features such as relatively wide but flat capillaries, fenestrated capillary walls and an enormous blood flow. The high flow rate results in a high oxygen tension in the tissue and is also of importance in the temperature control of the eye. The capillary wall is permeab...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00127638
更新日期:1983-02-01 00:00:00
abstract:PURPOSE:Retinal vascular abnormalities are associated with choroidal melanoma. Although tumor ischemia, resulting in soluble angiogenic factor production, is a proposed etiology of these abnormalities, other sources of ischemia may also contribute. Mushroom-shaped choroidal melanomas have increased loss of the overlyin...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1021170402679
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0498-2
更新日期:2018-04-01 00:00:00
abstract::Corneal ulcer is a devastating corneal disease which is potentially sight-threatening and conventionally is treated by topical antibiotics and in some cases with more invasive procedures such as keratoplasty. The aim of this study is to evaluate the efficacy of corneal collagen cross-linking in resistant corneal ulcer...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1007/s10792-012-9633-2
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS:A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolle...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0608-1
更新日期:2018-08-01 00:00:00
abstract::To look for a correlation between or the effect of anisometropia amblyopia on retrobulbar blood flow parameters. Peak systolic velocity (PSV) and end-diastolic velocity (EDV) of the ophthalmic artery (OA), central retinal artery (CRA), and temporal posterior ciliary artery (tPCA) were measured with color Doppler imagi...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9572-y
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis. METHODS:Case report. RESULTS:A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone b...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9126-x
更新日期:2008-08-01 00:00:00
abstract::Sarcoidosis is a multisystem disease characterized by enhanced immune responses at sites of involvement. To elucidate the immunopathogenesis of ophthalmic lesions, cell infiltrates in biopsies from conjunctiva and other tissues involved (lungs, lymph nodes, skin) were studied in 26 patients with active sarcoidosis in ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00131162
更新日期:1990-01-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of Nd.YAG-laser treatment on retinal function. All the patients treated showed a temporary decrease of visual acuity immediately after treatment. The ERG and EOG recordings were identical before and after treatment. The Umazume-Ohta test showed temporary central or ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF02027893
更新日期:1987-10-01 00:00:00
abstract::Sensorineural hearing loss is the most common disease associated with systemic retinitis pigmentosa (RP). We have conducted an epidemiological study to assess the correlation of age at onset of visual symptoms and hearing loss associated with RP. Epidemiological data was derived from a questionnaire-based study of pat...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-005-2035-y
更新日期:2004-10-01 00:00:00
abstract::To determine changes in choroidal thickness in patients with central serous chorioretinopathy (CSCR) during the first 3 months after initial diagnosis and assess variable therapeutic interventions via enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). In this prospective study, choroidal th...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-013-9774-y
更新日期:2014-02-01 00:00:00
abstract::Thirty-three cases of aphakic retinal detachment have been treated by pars plana vitrectomy and retinopexy. This procedure allowed us to lower the incidence of postoperative massive periretinal proliferation from 15,4%, in a series that was performed by a classical method, to 6% in the pars plana treated group. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00138265
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:To investigate the effects of 1% cyclopentolate hydrochloride and 1% tropicamide eye drops on aqueous flare measurements by using the laser flare meter. METHODS:One hundred forty eight eyes of 83 patients with inactive uveitis were enrolled. The patients were randomly assigned to receive either 1% tropicamide ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01639-3
更新日期:2020-11-16 00:00:00
abstract:PURPOSE:Our purpose is to describe a safe and easy technique for the removal of the BrightOcular cosmetic iris implants. Our technique involves cutting the implant into five parts rather than removal as a whole with less intraocular manipulation and no rotation of the implant. METHODS:We have used this technique in tw...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01328-1
更新日期:2020-06-01 00:00:00
abstract::To report a case of bilateral granulomatous post-streptococcal syndrome uveitis in association with reactive arthritis as manifestation of post-streptococcal syndrome. To our knowledge, this could represent the first reported case in the literature. A 9-year-old girl, with no past ocular history, presented with a 5-da...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9626-1
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:To elucidate the role of trabeculectomy in advanced glaucoma. MATERIALS AND METHODS:Only patients with primary open-angle glaucoma were selected. All patients who had cup-disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Tar...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0797-7
更新日期:2019-01-01 00:00:00