Abstract：
:We report our experience with photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) in young adult patients. This was a retrospective study of young adults with CNV treated with PDT. Data collected included age, diagnosis, type and size of CNV, number of treatments, visual outcome, and side effects. Ten patients (11 eyes) were included in the study (mean age 27.2 +/- 13.3 years). Etiologies included multifocal choroiditis (3 eyes), idiopathic CNV (5 eyes), central serous chorioretinopathy (1 eye), and toxoplasma (2 eye). The mean number of treatments was 2 +/- 0.7 and the mean follow-up time was 13.1 +/- 9.5 months. Initial visual acuity (VA) ranged from 20/25 to 20/1,200 (mean logMAR 0.6 +/- 0.5), and improved to 20/20 to 20/250 (mean logMAR 0.46 +/- 0.4) (P = 0.51). Of the four eyes that received additional treatment with oral steroids, one of which also received intravitreal bevacizumab (Avastin) injections, all had visual acuity improvement of 2 or more lines, while only two of seven eyes that received PDT alone showed such improvement. PDT can improve visual outcome in a subgroup of young patients with subfoveal CNV especially when supplemented with oral steroid and bevacizumab injections.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Ehrlich R,Kramer M,Rosenblatt I,Weinberger D,Mimouni K,Priel E,Axer-Siegel Rdoi
10.1007/s10792-010-9346-3subject
Has Abstractpub_date
2010-08-01 00:00:00pages
345-51issue
4eissn
0165-5701issn
1573-2630journal_volume
30pub_type
杂志文章abstract：:Myelinated retinal nerve fibers (MRNF) represent an asymptomatic developmental anomaly in which myelin sheaths extend to a group of retinal nerve fibers along their intraocular portion. The additional volume of the myelin sheaths causes displacement of the axons toward the vitreous body. We investigated the effect of ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0207-6
更新日期：2016-12-01 00:00:00
abstract：:To describe a congenital retinal macrovessel with macular thickening. This case was investigated using fundus photography, fluorescein angiography, Spectralis optical coherence tomography and a 10-2 visual field test. A 23-year-old man was referred to our clinic with decreased vision in the right eye. Fundus examinati...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9402-z
更新日期：2011-02-01 00:00:00
abstract：:In a prospective study of untreated ocular hypertension 117 eyes were non-exfoliative and 20 eyes exfoliative. The percentage of optic disc pallor was significantly larger in the exfoliative than in the non-exfoliative group, whereas no significant differences were found in IOP or in the visual field. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028632
更新日期：1989-01-01 00:00:00
abstract：:An animal model of keratomycosis was used to study the interaction between the new enzyme antifungal compound mycolase II and the polyene antifungal antibiotic pimaricin. Well established corneal infection caused by an ocular pathogenic candida albicans on New Zealand white male rabbits were treated with 3% mycolase I...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00149150
更新日期：1982-11-01 00:00:00
abstract：PURPOSE:To evaluate the clinical outcome of patients who received a Baerveldt implant for refractory glaucoma and to identify factors which may influence the outcome. METHODS:Retrospective study including 51 eyes of 51 patients with medically uncontrolled glaucoma who underwent Baerveldt implant surgery between June 1...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1016335313035
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To report a case of bilateral Terson Syndrome with sub inner limiting membrane hemorrhage associated with a rare finding: perimacular fold. METHODS:The patient, a 34 years old female with aneurysmal subarachnoid hemorrhage and bilateral Terson syndrome was admitted to the Ophthalmology department, complaining ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0822-5
更新日期：2019-02-01 00:00:00
abstract：:To determine changes in choroidal thickness in patients with central serous chorioretinopathy (CSCR) during the first 3 months after initial diagnosis and assess variable therapeutic interventions via enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). In this prospective study, choroidal th...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9774-y
更新日期：2014-02-01 00:00:00
abstract：:The purpose of this study was to report on the occurrence and management of posterior synechiae (PS) in three hyperopic eyes after iris-fixated anterior chamber phakic IOL implantation. This is a case report of a 55-year-old man and a 55-year-old lady who had undergone iris-fixated anterior chamber phakic IOL implanta...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0202-y
更新日期：2016-12-01 00:00:00
abstract：:To report a patient with optic disc pit who showed decreased inner diameter of the optic disc pit along with resolution of recurrent macular detachment after pars plana vitrectomy. Pneumatic retinopexy and peripapillary laser photocoagulation was performed in a 28-year-old female with optic disc pit and serous macular...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9656-8
更新日期：2013-04-01 00:00:00
abstract：PURPOSE:To analyze the demographic patterns, clinical characteristics, and treatment protocols of optic neuropathies. MATERIALS AND METHODS:The hospital data of patients with optic neuropathy admitted to the Department of Neuro-ophthalmology in a tertiary referral center in Turkey between January 2010 to January 2017 ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0799-5
更新日期：2019-01-01 00:00:00
abstract：:Uveitis is a complex intraocular inflammatory disease resulting from several aetiological entities that are linked to geographical, genetic and socioeconomic variables. The purpose of this study was to provide an overview of the distribution patterns of uveitis as seen in a nationwide referral centre at a community ho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9359-y
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:This study compares outcomes and complications of scleral-fixated intraocular lens implantation between 2 levels of surgeons. METHODS:A retrospective case series of patients undergoing scleral-fixated intraocular lens implantation at Prince of Wales Hospital, Hong Kong, between May 2012 and April 2017 were rev...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01480-8
更新日期：2020-11-01 00:00:00
abstract：:To analyze the pattern of intermediate uveitis (IU) in a referral center in Tunisia, North Africa. A retrospective, descriptive study of 87 consecutive patients (145 eyes) examined at the Department of Ophthalmology of Monastir (Tunisia) from January 1996 to August 2008. All patients underwent an extensive ocular and ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9352-5
更新日期：2010-10-01 00:00:00
abstract：:Fifty patients who developed preretinal or papillary neovascularization following tributary vein occlusion were treated by laser photocoagulation. Areas of non-perfused retina within the distribution of the obstructed vein were identified by fluorescein angiography and ablated using moderately intense laser photocoagu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130697
更新日期：1981-05-01 00:00:00
abstract：:We report our experience with three cases of Epstein-Barr virus (EBV)-associated uveitis. These patients had the following common clinical features: 1) a common cold-like prodrome, 2) bilateral involvement, 3) severe acute anterior uveitis with fibrinous exudate, 4) granulomatous anterior uveitis in the chronic stage,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163559
更新日期：1990-10-01 00:00:00
abstract：PURPOSE:To compare stage of visual field loss (VFL) and age at diagnosis between patients with different types of glaucoma with regard to glaucoma screening and driving ability. METHODS:In a cross-sectional study of 1988 consecutive patients with different types of glaucoma VFL at diagnosis and age at diagnosis were a...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0477-7
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:To report the fluorescein fundus angiographic (FFA) findings in the different clinical stages of Vogt-Koyanagi-Harada (VKH) patients. METHODS:Retrospective, transversal and descriptive study. All patients underwent FFA at least in one occasion. Patients with incomplete clinical files or a deficient FFA were ex...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9027-4
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:A study of the characteristics and the results obtained in 99 consecutive eyes operated on for rhegmatogenous retinal detachment associated with aphakia or pseudophakia in order to find the predictive factors of poor anatomical and functional results. METHODS:The authors retrospectively reviewed the files o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00176882
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To evaluate the effects of epiretinal membrane (ERM) formation on the anatomic and functional results of subjects with diabetic macular edema (DME) who are receiving intravitreal aflibercept injections (IAIs). MATERIALS AND METHODS:This retrospective comparative study includes 29 eyes with DME (Group 1) and 43...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01444-y
更新日期：2020-10-01 00:00:00
abstract：:Central serous chorioretinopathy (CSCR) is characterized by neurosensory retinal detachment. Because the retina pigment epithelium and choroidal pathology is the current mechanism in CSCR, many studies in the literature focused on the outer retinal layers. There is little information about the functional or histologic...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0278-4
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To provide normal corneal elevation data for a large Caucasian population and to determine the impacts on these data of age, sex, axial length (AXL) and horizontal white-to-white (WW). SETTING:Centro Internacional de Oftalmología Avanzada, Madrid, Spain. DESIGN:Retrospective, cross-sectional, observational. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1028-6
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:The aim of this study is to compare the effect of different riboflavin solutions (hypotonic and isotonic) used during accelerated corneal cross-linking (CXL) on the mean depth of the demarcation line (DDL) formed in corneal stroma. METHODS:This prospective, cross-sectional study included 38 eyes of 26 patients...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0951-x
更新日期：2019-06-01 00:00:00
abstract：:There has been great controversy about the pathogenesis of the focal changes in the retinal pigment epithelium (RPE) causing detachment of the neurosensory retina in central serous chorioretinopathy (CSC). This study was performed to evaluate changes in choroidal perfusion in 15 patients with CSC. Fluorescein and indo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133176
更新日期：1995-01-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0498-2
更新日期：2018-04-01 00:00:00
abstract：:We present an unusual case of polypoidal choroidal vasculopathy (PCV) lying above the retinal pigment epithelium (RPE) in a 60-year-old Caucasian female. PCV lesions are typically located beneath the RPE layer. However, they may rarely lie above the level of the RPE due to a discontinuity in the RPE and Bruch's membra...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9681-7
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To describe the intraoperative complications and the learning curve of microincision cataract surgery assisted by femtosecond laser (FLACS) with bimanual technique performed by an experienced surgeon. METHODS:It is a prospective, observational, comparative case series. A total of 120 eyes which underwent biman...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0776-z
更新日期：2019-01-01 00:00:00
abstract：:Various techniques which use monoclonal antibodies to detect Chlamydia trachomatis in clinical specimens are reviewed. An investigation comparing the efficacy of immunofluorescent staining with Giemsa staining in detecting Chlamydia in conjunctival scrapings from cases of active trachoma is presented. Sixty-two eyes o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133786
更新日期：1988-01-01 00:00:00
abstract：PURPOSE:To evaluate the influence of strong fixation preference on clinical and surgical outcomes, in non-amblyopic patients with basic-type intermittent exotropia (IXT). MATERIALS AND METHODS:The records of patients were retrospectively investigated. Non-amblyopic patients with the diagnosis of basic-type IXT were en...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01603-1
更新日期：2020-10-14 00:00:00
abstract：:This paper builds on results of a previous paper on the prevalence of trachomatous visual impairment as the foundation for assessing the global burden of trachomatous blindness and low vision: approximately 2.9 million cases of trachomatous blindness and 3.8 million low visioned corresponding to a global prevalence of...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00130921
更新日期：1995-01-01 00:00:00
abstract：BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAIDs), as an alternative, are replacing corticosteroids in ocular inflammatory diseases. Diclofenac has been used mainly topically, and recent focus has been on intravitreal delivery. Both of these methods have been shown to have complications in long-term application....
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1007/s10792-016-0428-8
更新日期：2018-02-01 00:00:00
