Abstract：
PURPOSE:The aim of this study is to compare the effect of different riboflavin solutions (hypotonic and isotonic) used during accelerated corneal cross-linking (CXL) on the mean depth of the demarcation line (DDL) formed in corneal stroma. METHODS:This prospective, cross-sectional study included 38 eyes of 26 patients. All patients underwent accelerated CXL due to progressive keratoconus. When the corneal epithelium was removed, 17 eyes of 12 patients with corneal thickness < 400 µm were categorized as Group 1, and 21 eyes of 14 patients with corneal thickness > 400 µm as Group 2. Hypotonic riboflavin was applied to Group 1 patients, and isotonic riboflavin to Group 2 patients. Anterior segment optical coherence tomography was performed on all patients by two independent observers at the end of the first and third months. RESULT:Group 1 included 5 male and 7 female patients with an average age of 25.1 ± 8.0 years, whereas Group 2 included 7 male and 7 female patients with an average age of 31.8 ± 10.12 years. At the end of the first month, the mean DDL in Group 1 and Group 2 was 180.32 ± 10.26 and 287.21 ± 15.01 µm, respectively. This difference was statistically significant (p < 0.05). CONCLUSION:Application of different riboflavin solutions was observed to have an effect on measured corneal thickness after saturation and the depth of the demarcation line. The use of hypotonic riboflavin results in swelling of the cornea and more superficial localization of the stromal demarcation line after CXL.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Ozek D,Kemer OE,Ozer PAdoi
10.1007/s10792-018-0951-xsubject
Has Abstractpub_date
2019-06-01 00:00:00pages
1329-1335issue
6eissn
0165-5701issn
1573-2630pii
10.1007/s10792-018-0951-xjournal_volume
39pub_type
杂志文章abstract：:To investigate subconjunctival bevacizumab as an adjuvant in first-time glaucoma filtration surgery, we conducted a non-comparative, interventional case series, enrolling consecutive patients with uncontrolled primary glaucomas. All patients underwent trabeculectomy with mitomycin C and received a 1.25 mg subconjuncti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9704-4
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To evaluate the accuracy of intraocular lens (IOL) power calculation in relation to optical biometry devices and refraction types. METHODS:Patients undergoing cataract phacoemulsification and insertion of the MX60 IOL were enrolled. Optical biometric measurements were performed with both IOLMaster 700 and Lens...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01355-y
更新日期：2020-07-01 00:00:00
abstract：:This study aimed to present precancerous and cancerous epithelial eyelid lesions, their histopathological features, and possible correlations with clinical parameters. The retrospective study included 147 formalin-fixed, paraffin-embedded samples. We studied precancerous and cancerous epithelial eyelid lesions. Preneo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0258-8
更新日期：2017-02-01 00:00:00
abstract：:To document the rate of self-reported compliance and glaucoma-related knowledge in Swiss patients and to identify risk factors for their poor compliance. This was an observational study, including a total of 200 consecutive patients already under glaucoma medication in two Swiss tertiary glaucoma clinics (Geneva and B...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9468-2
更新日期：2011-10-01 00:00:00
abstract：PURPOSE:To compare the systemic and ocular characteristics and laboratory findings of patients developing toxic anterior segment syndrome (TASS) after uneventful phaco surgery with unaffected subjects undergoing the same surgery in the same session. DESIGN:A retrospective case-control study. METHODS:The study group c...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0418-x
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To investigate the natural course, visual outcome, and risk factors for visual loss after nonarteritic anterior ischemic optic neuropathy (NAION) attack in Chinese patients from a tertiary medical center in Southern Taiwan. METHODS:This is a longitudinal observational study that included sixty NAION patients, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01448-8
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Evidence has accumulated suggesting that various inflammatory cytokines are involved in the progress of diabetic retinopathy (DR), but there are few studies concerning the relationship between individual cytokines levels in the aqueous humor (AH) and the severity of DR. This study aimed to explore the differenc...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01463-9
更新日期：2020-10-01 00:00:00
abstract：:Clinical trials are often used to evaluate the efficacy of a given treatment. The results of clinical trials however do not always agree with a clinician's experience or intuition. The merits and demerits of Clinical Trials versus Intuition are discussed by using the laser photocoagulation trials of Proliferative Diab...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159835
更新日期：1986-05-01 00:00:00
abstract：:Several different sets of criteria have been proposed to establish the diagnosis of Vogt-Koyanagi-Harada disease (VKH). Various investigators have used the criteria proposed by Sugiura, those proposed by by the American Uveitis Society as well as the revised diagnostic criteria proposed by the First VKH International ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9021-x
更新日期：2007-04-01 00:00:00
abstract：PURPOSE:To evaluate by Environmental Scanning Electron Microscopy (ESEM) the corneal incision architecture after intraocular lens (IOL) implantation in pig eyes, using manual, automated injectors or preloaded delivery systems. METHODS:Twenty-four pig eyes underwent IOL implantation in the anterior chamber using three ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0825-2
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:To evaluate the long-term course of primary angle-closure ocular hypertension and primary open-angle ocular hypertension and possible risk factors for progression to glaucoma. METHODS:A total of 109 eyes of 109 ocular hypertension (OHT) patients with a minimum follow-up period of 5 years having complete ocular...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0872-8
更新日期：2019-04-01 00:00:00
abstract：:Myelinated retinal nerve fibers (MRNF) represent an asymptomatic developmental anomaly in which myelin sheaths extend to a group of retinal nerve fibers along their intraocular portion. The additional volume of the myelin sheaths causes displacement of the axons toward the vitreous body. We investigated the effect of ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0207-6
更新日期：2016-12-01 00:00:00
abstract：:To evaluate the clinical efficacy of transcutaneous everting sutures for lower eyelid involutional entropion in Chinese patients. A retrospective, non-comparative, interventional case series. This retrospective study consecutively reviewed the medical records of all patients with involutional lower eyelid entropion wh...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9893-5
更新日期：2014-08-01 00:00:00
abstract：:The purpose of this study was to evaluate the dynamic reality of the corneal transplant (CT) waiting list and if the CT candidates are really eager to operation. We evaluated the response of consecutive 96 CT candidates to call for operation. The age, functional visual acuity, CT indication, waiting period, and the ex...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0101-7
更新日期：2016-04-01 00:00:00
abstract：:Spontaneous hyphema has been linked to many conditions. We describe a patient with recurrent spontaneous hyphema caused by an abnormal angle vessel without associated rubeosis iridis, glaucoma, or other vascular abnormalities as documented by iris fluorescein angiography. After treatment with several sessions of argon...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136495
更新日期：1985-09-01 00:00:00
abstract：PURPOSE:To investigate complex and different phenotypes in seven Chinese patients diagnosed with Bardet-Biedl syndrome (BBS) and carrying pathogenic mutations. METHODS:Seven unrelated BBS patients were enrolled. Their medical and ophthalmic histories were reviewed, and comprehensive clinical examinations, such as fund...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01415-3
更新日期：2020-09-01 00:00:00
abstract：UNLABELLED:The purpose of this study is to evaluate the effect of trephination with free scleral auto-implant plug exposed to Mitomycin-C out of the eye, in surgical treatment of primary open-angle glaucoma (POAG), in comparison with efficacy of trabeculectomy with MMC (32 eyes with POAG of patients, younger than 55 ye...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00212952
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To evaluate circular neodymium: YAG laser incision in cases of anterior capsular contraction syndrome (ACCS) by comparing it to radial Neodymium: YAG laser incision as for efficacy and safety. SETTINGS:Ophthalmology Department, Benha University Hospitals. METHODS:The study was done on 74 eyes of 66 patients w...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-019-01094-9
更新日期：2019-11-01 00:00:00
abstract：:The main visual field indices of Flammer and the analogous ones of Heijl have been compared based on a population of 113 glaucomatous visual fields. It is shown that for the population studied, the differences between the two sets of indices are negligible for Octopus G1 program results and that they may thus be used ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128955
更新日期：1991-09-01 00:00:00
abstract：INTRODUCTION:Uveitis encompasses a wide variety of sight-threatening diseases characterized by intraocular inflammation. It is often classified as infectious and non-infectious uveitis. Unlike infectious uveitis, a distinct infectious agent cannot be identified in non-infectious uveitis and disease origin is usually au...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0984-1
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:To evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model. METHODS:A chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.1%, Met_0.5%, sham...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0922-2
更新日期：2019-05-01 00:00:00
abstract：:Blindness in diabetics is largely due to retinopathy and/or cataract. Hyperglycaemia and the duration of diabetes are major risk factors for the development of cataract and retinopathy. This review details some of the reactions of glucose that are relevant to the development of complications, and follows the elucidati...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00150976
更新日期：1991-01-01 00:00:00
abstract：:The purpose of this study was to compare the keratometry (K) values obtained by the Scheimpflug camera combined with placido-disk corneal topography (Sirius) and optical biometry (Lenstar) for intraocular lens (IOL) power calculation before the cataract surgery, and to evaluate the accuracy of postoperative refraction...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0330-4
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation syndrome (PEX) is a late onset disorder of extracellular matrix turnover, associated systemically with cardiovascular and cerebrovascular disease. To evaluate the suggested association of polymorphisms of homocysteine metabolism genes MTHFR (rs1801131, rs1801133) and MTHFD1 (rs8006686) with PE...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0498-2
更新日期：2018-04-01 00:00:00
abstract：:The purpose of this study was to evaluate the changes in the severity of conjunctivochalasis after cataract surgery performed via a superior conjunctival sclerocorneal incision. Prospective investigation was performed in a consecutive series of 36 eyes of 36 patients aged 62-85 years who underwent phacoemulsification ...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-016-0328-y
更新日期：2017-06-01 00:00:00
abstract：PURPOSE:To explore whether retrobulbar administration of nerve growth factor (NGF) can restore visual function of streptozotocin-induced diabetes rats. METHODS:A high-sucrose/high-fat diet and single injection of streptozotocin (STZ) were used in modeling diabetes. During week 13-15 after STZ injection, diabetic rats ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01537-8
更新日期：2020-12-01 00:00:00
abstract：:The glistening and delayed opacification of intraocular lenses (IOLs) has been reported in literature as a late and permanent change in the acrylic IOL due to temperature change. We report a case in which clouding and opacification of an IOL occurred intraoperatively within a few seconds of implantation into the capsu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9481-5
更新日期：2011-12-01 00:00:00
abstract：:17 patients with intraretinal magnetic foreign bodies and vitreous hemorrhage are reported. 15 patients underwent a primary surgical repair consisting of a watertight wound closure and removal of the already swelling cataractous lens in 5 cases. All patients had vitrectomy during the second postinjury week. The foreig...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02279868
更新日期：1989-09-01 00:00:00
abstract：:To analyze the pattern of intermediate uveitis (IU) in a referral center in Tunisia, North Africa. A retrospective, descriptive study of 87 consecutive patients (145 eyes) examined at the Department of Ophthalmology of Monastir (Tunisia) from January 1996 to August 2008. All patients underwent an extensive ocular and ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9352-5
更新日期：2010-10-01 00:00:00
abstract：:I have developed two protective caps that fit on the viewing windows of the indirect ophthalmoscope. These caps contain filters that absorb the argon laser beam and protect the operator's eyes during endolaser treatment. ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00225937
更新日期：1986-04-01 00:00:00
