Monoclonal antibodies in the laboratory diagnosis of trachoma.

Abstract:

:Various techniques which use monoclonal antibodies to detect Chlamydia trachomatis in clinical specimens are reviewed. An investigation comparing the efficacy of immunofluorescent staining with Giemsa staining in detecting Chlamydia in conjunctival scrapings from cases of active trachoma is presented. Sixty-two eyes of schoolboys with moderate to severe trachoma were studied. Giemsa staining detected chlamydial inclusion bodies in 34 percent of the specimens. Free elementary bodies were detected by fluorescent monoclonal antibody in 21 percent. Eleven percent were positive by both Giemsa and immunofluorescence and 55 percent were positive by either Giemsa and/or immunofluorescence. The addition of fluorescent monoclonal antibody assay to routine Giemsa staining resulted in an increase in the yield of positive specimens by 29 percent.

journal_name

Int Ophthalmol

authors

Taylor PB,Burd EM,Tabbara KF

doi

10.1007/BF00133786

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

81-6

issue

1

eissn

0165-5701

issn

1573-2630

journal_volume

12

pub_type

杂志文章
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    更新日期:1998-01-01 00:00:00

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    doi:10.1007/BF00132688

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    pub_type: 杂志文章

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    更新日期:2015-08-01 00:00:00

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    更新日期:2015-08-01 00:00:00

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    更新日期:1993-02-01 00:00:00

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    更新日期:1998-01-01 00:00:00

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    更新日期:2018-08-01 00:00:00

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    doi:10.1007/s10792-018-0962-7

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    更新日期:2019-07-01 00:00:00

  • Retained lens fragment in the anterior segment as a cause of recurrent anterioruveitis.

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    doi:10.1007/s10792-008-9279-2

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  • The value of "en toto" globe submission in the assessment of high-risk retinoblastoma cases and staging.

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    pub_type: 杂志文章

    doi:10.1007/BF00159835

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    更新日期:1986-05-01 00:00:00

  • External ophthalmomyiasis: a case series.

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    pub_type: 杂志文章

    doi:10.1007/s10792-012-9644-z

    authors: Carrillo I,Zarratea L,Suárez MJ,Izquierdo C,Garde A,Bengoa A

    更新日期:2013-04-01 00:00:00

  • Bilateral orbital tumor formation and isolated facial palsy in Waldenstrom's macroglobulinemia.

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    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-007-9037-x

    authors: Kumar S,Das S,Goyal JL,Chauhan D,Sangit V

    更新日期:2005-12-01 00:00:00

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    journal_title:International ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10792-016-0339-8

    authors: Fariña N,Samudio M,Carpinelli L,Nentwich MM,de Kaspar HM

    更新日期:2017-08-01 00:00:00

  • The effect of isosorbide-mononitrate eye drops on the human intraocular pressure and aqueous humor dynamics.

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    journal_title:International ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF00171028

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    更新日期:1991-07-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2020-11-01 00:00:00

  • Short-term change in higher-order aberrations after mitomycin-C-augmented trabeculectomy.

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    更新日期:2010-10-01 00:00:00

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