Abstract：
PURPOSE:To evaluate the importance of "en toto" globe submission in the assessment of high-risk pathological findings in retinoblastoma cases, aiming at identifying the additional value from full globe examination of enucleated eyes (including the calottes). METHODS:Retrospective histopathological case series of eighty-one enucleated globes with the clinical diagnosis of retinoblastoma, histopathologically examined at King Khaled Eye Specialist Hospital (KKESH) between January 2010 and December 2013. We included retinoblastoma eyes with any type of invasion (more than pT1) in which the globe was submitted "en toto." All cases were histopathologically classified according to the American Joint Cancer Classification (AJCC TNM classification, 2009 6th edition). RESULTS:81 enucleated globes were examined, out of which 30 globes were classified as high-risk cases (more than pT1). 8 cases had massive choroidal invasion in both the PO sections and calottes. 5 cases had focal choroidal invasion in both. One case has massive choroidal invasion in calottes with very superficial ON head invasion. Two cases were found to have focal choroidal invasion in the calottes with prelaminar ON invasion. In these three cases (10%), the presence of focal or massive choroidal invasion in the calottes has affected the classification. CONCLUSIONS:This study consolidates the guidelines recommended in the consensus meeting: from the International Retinoblastoma Staging Working Group on the pathology guidelines for the examination and evaluation of prognostic risk factors in retinoblastoma eyes. Full globe submission and examination should be the routine accepted practice universally even in underdeveloped countries.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Alkatan HM,ALBalawi H,Maktabi AMYdoi
10.1007/s10792-016-0410-5subject
Has Abstractpub_date
2018-02-01 00:00:00pages
35-41issue
1eissn
0165-5701issn
1573-2630pii
10.1007/s10792-016-0410-5journal_volume
38pub_type
杂志文章abstract：:This study reports the outcomes of therapeutic penetrating keratoplasties, defined as keratoplasties performed to eradicate active infectious corneal diseases or to repair a structural defect of the cornea. The records of 24 eyes of 24 patients (17 female and 7 male) treated with therapeutic penetrating keratoplasty b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9931-y
更新日期：2015-04-01 00:00:00
abstract：:The purpose of this study is to investigate whether subconjunctival and/or intrastromal Bevacizumab injections could help to prevent graft failure in high-risk keratoplasties. Twenty seven eyes of 27 patients, affected by high immune rejection risk and corneal neovascularization, were involved in this prospective inte...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-9938-4
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:Oncocytoma is rarely found around the lacrimal punctum. We describe a case of oncocytoma of the peripunctum. METHODS:Case report. RESULTS:An 88-year-old patient presented with a upper peripunctal mass in the left eye. The tumor was completely excised including the lacrimal punctum and part of the canalicul...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9008-7
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:To gain an insight into the manufacturing and fitting of artificial eyes in children and potential improvements to the process. METHOD:An online qualitative survey was distributed to 39 ocularists/prosthetists in Europe and Canada. Participants were recruited through purposive sampling, specifically maximum va...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-016-0383-4
更新日期：2017-10-01 00:00:00
abstract：:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9463-7
更新日期：2011-10-01 00:00:00
abstract：PURPOSE:To determine whether there are angiographic differences among normal, preperimetric and advanced glaucoma eyes using indocyanine green angiography with SLO. This method was chosen because of its sensibility to detect peripapillary capillary vessels. METHODS:Scanning laser opthalmoscopy was preformed on normal ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1014431404096
更新日期：2001-01-01 00:00:00
abstract：:The glistening and delayed opacification of intraocular lenses (IOLs) has been reported in literature as a late and permanent change in the acrylic IOL due to temperature change. We report a case in which clouding and opacification of an IOL occurred intraoperatively within a few seconds of implantation into the capsu...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-011-9481-5
更新日期：2011-12-01 00:00:00
abstract：PURPOSE:To explore whether retrobulbar administration of nerve growth factor (NGF) can restore visual function of streptozotocin-induced diabetes rats. METHODS:A high-sucrose/high-fat diet and single injection of streptozotocin (STZ) were used in modeling diabetes. During week 13-15 after STZ injection, diabetic rats ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01537-8
更新日期：2020-12-01 00:00:00
abstract：:To evaluate the efficacy of golimumab on severe and frequent recurrent anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis. In this study, 15 eyes of 12 HLA-B27-positive AS patients with resistant anterior uveitis who received 50 mg of subcutaneous golimumab (Gol) per month due to frequent uveiti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0239-y
更新日期：2017-02-01 00:00:00
abstract：:In 15 eyes with uncontrolled aphakic/pseudophakic glaucoma, trabeculectomy with anterior vitrectomy was performed. Mean pre-operative intraocular pressure (IOP) was 38.2 +/- 6.7 mmHg and mean post operative IOP was 19.3 +/- 5.2 mmHg after follow-up of 11.2 2 months. The anterior chamber maintainer technique during vit...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00153920
更新日期：1991-05-01 00:00:00
abstract：PURPOSE:To determine the cytokine levels in vitreous samples of diabetic macular edema (DME) patients in comparison with nondiabetic patients, and to evaluate the effect of subretinal fluid on the cytokine levels of vitreous samples. METHODS:In this prospective case-control study, 11 eyes of 11 patients with DME and s...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0874-6
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis. METHODS:Case report. RESULTS:A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone b...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9126-x
更新日期：2008-08-01 00:00:00
abstract：:The association between HLA-A29 and birdshot chorioretinopathy is the strongest of all associations between HLA and disease. Determination of HLA-A29 is even of diagnostic significance. The association between HLA-B27 and acute anterior uveitis (AAU) is much weaker, but B27 positive AAU may be considered as a distinct...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/BF00163552
更新日期：1990-10-01 00:00:00
abstract：:The purpose of this study was to investigate the reproducibility of choroidal thickness measurements in normal subjects on 3 spectral domain optical coherence tomography instruments, namely: Zeiss Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA), Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany), ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0306-4
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVES:To determine the common eye diseases as well as the prevalence and causes of blindness and visual impairment in young adult residents of rural areas of Anambra State, Nigeria. MATERIALS AND METHODS:Three rural villages in Anambra State, Nigeria were selected by simple random sampling. A structured questionn...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1006338013075
更新日期：1998-01-01 00:00:00
abstract：PURPOSE:To report a case of subtotal iridodialysis that was repaired using suturing with the assistance of a guide needle. PATIENT AND METHODS:A 52-year-old man had subtotal iridodialysis of approximately 300° with massive hyphema and vitreous hemorrhage after blunt trauma. The patient was treated with pars plana vitr...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0465-y
更新日期：2018-02-01 00:00:00
abstract：:Melanoma-associated retinopathy is a paraneoplastic retinopathy associated mostly with cutaneous melanoma. In most cases it presents months to years after diagnosis of primary cutaneous melanoma was made or after recurrence. We describe a 55-year-old male patient who presented with symptoms of decreased vision and pho...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9564-y
更新日期：2012-08-01 00:00:00
abstract：:Infrequently, vitreomacular traction is released through the spontaneous development of complete posterior vitreous detachment (PVD). PVD caused by laser photocoagulation has also been reported. A 62-year-old woman with ischemic branch retinal vein occlusion showed decreased vision in the affected eye due to vitreomac...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9166-2
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS:In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history o...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0595-2
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:To evaluate circular neodymium: YAG laser incision in cases of anterior capsular contraction syndrome (ACCS) by comparing it to radial Neodymium: YAG laser incision as for efficacy and safety. SETTINGS:Ophthalmology Department, Benha University Hospitals. METHODS:The study was done on 74 eyes of 66 patients w...
journal_title：International ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10792-019-01094-9
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To compare the efficacy of intravitreal injection of ranibizumab, dexamethasone implant and aflibercept for the management of macular edema (ME) related to branch retinal vein occlusion (BRVO). METHODS:This retrospective and comparative study included 62 eyes of 62 patients with BRVO and ME. Patients received ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0618-z
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH). METHODS:The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluores...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0443-4
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:To investigate the natural course, visual outcome, and risk factors for visual loss after nonarteritic anterior ischemic optic neuropathy (NAION) attack in Chinese patients from a tertiary medical center in Southern Taiwan. METHODS:This is a longitudinal observational study that included sixty NAION patients, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01448-8
更新日期：2020-10-01 00:00:00
abstract：:Early-onset sarcoidosis (EOS) and Blau syndrome are rare auto-inflammatory diseases characterized by a triad of skin rash, granulomatous uveitis, and symmetrical polyarthritis occurring in early childhood. In this paper, we describe a case report very interesting for the multidisciplinary management (pediatric rheumat...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-015-0135-x
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:To report a large, consecutive series of endophthalmitis of all causes managed at a tertiary referral retina center. METHODS:Retrospective chart review of all cases diagnosed with endophthalmitis that received reatment and follow-up between January 2000 and January 2005. RESULTS:A total of 67 patients were di...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9068-3
更新日期：2007-08-01 00:00:00
abstract：PURPOSE:Proliferative vitreoretinopathy (PVR) is characterized by the formation of cellular membranes on the detached retina and also in the vitreous. Glial cells can be found in epiretinal and subretinal membranes from eyes with PVR, proliferative diabetic retinopathy (PDR), idiopathic macular pucker, uveitis and othe...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1022509614815
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To describe the intraoperative complications and the learning curve of microincision cataract surgery assisted by femtosecond laser (FLACS) with bimanual technique performed by an experienced surgeon. METHODS:It is a prospective, observational, comparative case series. A total of 120 eyes which underwent biman...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0776-z
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of long-tube shunt surgery (LTSS) without valve in uveitic glaucoma (UG) eyes. METHODS:We retrospectively analyzed the data of 45 UG eyes that underwent only LTSS or LTSS combined with trabeculectomy (TLE) (LTSS/TLE). The UG eyes were analyzed by categorizing them into granulomatous/no...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01601-3
更新日期：2020-10-14 00:00:00
abstract：:Diplopia is a very disturbing condition that has been reported as a complication of several surgical procedures. The following review aims to identify the ocular and nonocular surgical techniques more often associated with this undesirable result. Diplopia is reported as an adverse outcome of some neurosurgical proced...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-014-9927-7
更新日期：2014-08-01 00:00:00
abstract：:Suprachoroidal hemorrhages were created in 15 albino rabbit eyes by injecting 0.1 cc of autologous blood into the suprachoroidal space. One day later, 10 of these eyes were treated with intravenous tissue plasminogen activator (TPA). Doses of 1 mg per kg were given to each rabbit over 2 to 3 hours by intravenous infus...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159862
更新日期：1990-07-01 00:00:00
