Abstract：
:Out of 49 patients diagnosed as having Stargardt's disease that have been clinically reviewed, 22 of these cases have been followed for a period up to 13 years. The cases have been studied in three subgroups, according to their fundus appearance. Patients from group I were those whose lesions were confined to the macula, showing no flecks in the retina. In group II the macular lesion was surrounded by perimacular flecks and in group III fundus flavimaculatus flecks were seen, diffusely scattered in the posterior pole. It appears that the prognosis of group I is better than the other groups, where surrounding flecks are seen in addition to the macular lesion. The follow-up indicates that the disease evolves with a rather large spectrum of expressivity. Assessment of a predictive factor for the evolution of the disease is not yet possible. However, the observation of a dark choroid appears to be strongly suggestive for a further centrifugal progression of the disease.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Gelisken O,De Laey JJdoi
10.1007/BF00137651subject
Has Abstractpub_date
1985-11-01 00:00:00pages
225-35issue
4eissn
0165-5701issn
1573-2630journal_volume
8pub_type
杂志文章abstract：PURPOSE:The aim of the study reported here was to assess the influence of serum HbA1c levels on foveal choroidal thickness in diabetic patients. METHODS:A total of 122 eyes from 122 patients who had type 2 DM were studied in this prospective, cross-sectional study. Patients were divided into three groups: 43 patients ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0668-2
更新日期：2018-10-01 00:00:00
abstract：:We studied the changes in the thickness of the retinal nerve fiber layer (RNFL) after surgery for idiopathic macular hole (MH) using spectral-domain optical coherence tomography (SD-OCT). Twenty eyes of 20 consecutive patients who underwent vitrectomy to close a MH were studied. The peripapillary RNFL thickness was me...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-013-9855-y
更新日期：2014-06-01 00:00:00
abstract：:We report our experience with three cases of Epstein-Barr virus (EBV)-associated uveitis. These patients had the following common clinical features: 1) a common cold-like prodrome, 2) bilateral involvement, 3) severe acute anterior uveitis with fibrinous exudate, 4) granulomatous anterior uveitis in the chronic stage,...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00163559
更新日期：1990-10-01 00:00:00
abstract：:The traditional opinion that increased intraocular pressure is the cause of glaucoma is controversial, probably mainly because of the fact that firm evidence for the value of pressure reduction is largely lacking. The present article reviews results from short term studies of visual fields before and after pressure re...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF02028651
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:The objective is to report a rare case of asymptomatic penetrating injury with a copper foreign body found during an examination for cataract surgery. METHOD:A case report. RESULTS:A 73-year-old woman had vision loss. Examination by pupil dilation disclosed a dark-brown metallic mass located under the anterio...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-007-9074-5
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To evaluate the effect of metronidazole ophthalmic solutions on corneal neovascularization (CNV) in a rat model. METHODS:A chemical burn was created in the right central cornea of 40 rats. Animals were randomized and distributed into four study groups (n = 10 rats per group) designated Met_0.1%, Met_0.5%, sham...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0922-2
更新日期：2019-05-01 00:00:00
abstract：UNLABELLED:We examined the immunocytochemical features of after cataract tissue and cataractous lens epithelium prior to cataract surgery and at the time of surgery. METHODS:This study included 23 cases. Antibodies against the following antigens were used: epidermal growth factor (EGF), EGF receptor (EGF-R), fibroblas...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1023/a:1010640118852
更新日期：1999-01-01 00:00:00
abstract：:The purpose of the study was to compare the accuracy of various biometric formulas for predicting postoperative refraction determined using applanation A-scan ultrasound. This retrospective comparative study included 485 eyes that underwent uneventful phacoemulsification with intraocular lens (IOL) implantation. Appla...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0195-6
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:To investigate the changes in the anterior chamber volume (ACV) with swept-source optical coherence tomography (SS-OCT) after cataract surgery and the factors that influence these ACV changes. METHODS:This was a prospective cohort study. Fifty-one patients who underwent cataract surgery were enrolled. Their AC...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-1012-1
更新日期：2019-08-01 00:00:00
abstract：PURPOSE:To examine the retinal layers' changes and alterations in retinal microvasculature in patients with rhegmatogenous retinal detachment (RRD) treated with pars plana vitrectomy (PPV). METHODS:Participants in this study were 103 patients with RRD, 85 macula off and 18 macula on, who were treated with PPV and gas ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01521-2
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To report a case of subtotal iridodialysis that was repaired using suturing with the assistance of a guide needle. PATIENT AND METHODS:A 52-year-old man had subtotal iridodialysis of approximately 300° with massive hyphema and vitreous hemorrhage after blunt trauma. The patient was treated with pars plana vitr...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0465-y
更新日期：2018-02-01 00:00:00
abstract：:We describe the first two cases of diffuse unilateral subacute neuroretinitis (DUSN) in the UK successfully treated with albendazole. Two patients are described who presented with unilateral reduction in vision, with clusters of yellow-white retinal lesions fading and reappearing in new locations of the fundus over a ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-010-9358-z
更新日期：2010-10-01 00:00:00
abstract：:In a randomized, double-masked, single drop study the effect of topical isosorbid-mononitrate (ISMO) 0.5% eye drops, the main metabolite of isosorbid-dinitrate, widely used in the treatment of coronary heart diseases, was studied in patients suffering from open angle glaucoma or ocular hypertension. There was no stati...
journal_title：International ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00171028
更新日期：1991-07-01 00:00:00
abstract：:To evaluate the potential benefit of intraocular pressure (IOP) reduction in normal-tension glaucoma (NTG) patients in South Korea. A retrospective, multi-center analysis of Korean NTG patients with 5-years follow-up, typical glaucomatous optic disc and/or visual field changes and no recorded IOP >21 mmHg. Progression...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10792-011-9463-7
更新日期：2011-10-01 00:00:00
abstract：:The purpose of this study was to evaluate the impact of intravitreal bevacizumab injections on the management and outcome of patients affected by retinal vein occlusions, their effectiveness on morphological and functional parameters, the modalities of long-term management and the need for additional laser treatment d...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-014-0002-1
更新日期：2014-12-01 00:00:00
abstract：:Trichiasis/Entropion are the severe consequences of chronic trachoma during early life. Blindness and vision loss is preventable with timely lid surgery to correct trichiasis. In a trachoma hyperendemic region of Central Tanzania, a two year follow-up survey was conducted among 205 women with trichiasis to determine t...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00919249
更新日期：1994-01-01 00:00:00
abstract：:This study aimed to present precancerous and cancerous epithelial eyelid lesions, their histopathological features, and possible correlations with clinical parameters. The retrospective study included 147 formalin-fixed, paraffin-embedded samples. We studied precancerous and cancerous epithelial eyelid lesions. Preneo...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0258-8
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:We sought to assess the risk factors associated with avascular fibrous membrane development in patients with retinopathy of prematurity (ROP). METHODS:This retrospective, cross-sectional study included premature infants diagnosed with ROP. Gestational age, birth weight, stage and zone of the ROP, the presence ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01484-4
更新日期：2020-11-01 00:00:00
abstract：:Acute and invasive fungal infections are usually seen in immunocompromised and debilitated patients. We report a young immunocompetent 28-year-old Indian male who presented with unilateral endogenous endophthalmitis in the left eye and was managed with pars plana vitreous surgery. The polymerase chain reaction from th...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9235-1
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:To evaluate the effects of epiretinal membrane (ERM) formation on the anatomic and functional results of subjects with diabetic macular edema (DME) who are receiving intravitreal aflibercept injections (IAIs). MATERIALS AND METHODS:This retrospective comparative study includes 29 eyes with DME (Group 1) and 43...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01444-y
更新日期：2020-10-01 00:00:00
abstract：:The purpose of the study was to evaluate the outcomes and possible complications of CXL performed with customized epithelial debridement technique to keratoconic corneas with the thinnest pachymetry values less than 400 µm. Nineteen eyes of 19 patients were included. The uncorrected (UCVA) and best corrected visual ac...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0234-3
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To evaluate the long-term course of primary angle-closure ocular hypertension and primary open-angle ocular hypertension and possible risk factors for progression to glaucoma. METHODS:A total of 109 eyes of 109 ocular hypertension (OHT) patients with a minimum follow-up period of 5 years having complete ocular...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-018-0872-8
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the corneal biomechanical parameters in patients with ankylosing spondylitis (AS) and to compare them with the healthy subjects. METHODS:Sixty patients with AS (study group) and 60 healthy subjects (control group) were enrolled in this prospective study. The study group wa...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-016-0368-3
更新日期：2017-08-01 00:00:00
abstract：:To investigate the correlation between the perifoveal capillary blood flow velocity (BFV) and the vitreous level of pigment epithelium-derived factor (PEDF) in patients with branch retinal vein occlusion (BRVO) and macular edema. In a retrospective interventional study of patients with BRVO and macular edema, undilute...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9584-7
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:To investigate the dry eye symptoms after cataract surgery in MGD patients and their relationships METHODS: The study included 115 patients (115 eyes) with age-related cataract that underwent uncomplicated cataract surgery, and the patients were divided into two groups according to the MGD diagnostic criteria...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-020-01294-8
更新日期：2020-05-01 00:00:00
abstract：:Sarcoidosis is a multisystem disease characterized by enhanced immune responses at sites of involvement. To elucidate the immunopathogenesis of ophthalmic lesions, cell infiltrates in biopsies from conjunctiva and other tissues involved (lungs, lymph nodes, skin) were studied in 26 patients with active sarcoidosis in ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00131162
更新日期：1990-01-01 00:00:00
abstract：:A 61-year-old male developed recurrent anterior uveitis over a period of 8 months after an uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery. This was subsequently found to be due to a retained lens fragment in the anterior segment, with complete resolution following surgica...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-008-9279-2
更新日期：2010-02-01 00:00:00
abstract：PURPOSE:To describe the intraoperative complications and the learning curve of microincision cataract surgery assisted by femtosecond laser (FLACS) with bimanual technique performed by an experienced surgeon. METHODS:It is a prospective, observational, comparative case series. A total of 120 eyes which underwent biman...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-017-0776-z
更新日期：2019-01-01 00:00:00
abstract：:The ocular surface is exposed to many chronic inflammatory stimuli, and goblet cell hyperplasia of the conjunctiva occurs in many situations. We report two cases of epithelial goblet cell hyperplasia with nonspecific chronic inflammation which occurred on the internal canthus of elderly people. These cases shared the ...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-015-0083-5
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:To evaluate the long-term safety and efficacy of infliximab therapy for refractory uveitis associated with Behçet's disease (BD). METHODS:We prospectively enrolled six patients who failed to respond to conventional immunosuppressive treatment. Infliximab infusions (5 mg/kg) were administered at weeks 0, 2, 6, ...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-006-9006-9
更新日期：2005-06-01 00:00:00
