Abstract:
:Evaluation of brain cluster activation using the functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) was sought in strabismic amblyopes. In this hospital-based case-control cross-sectional study, fMRI and DTI were conducted in strabismic amblyopes before initiation of any therapy and after visual recovery following the administration of occlusion therapy. FMRI was performed in 10 strabismic amblyopic subjects (baseline group) and in 5 left strabismic amblyopic children post-occlusion therapy after two-line visual improvement. Ten age-matched healthy children with right ocular dominance formed control group. Structural and functional MRI was carried out on 1.5T MR scanner. The visual task consisted of 8 Hz flickering checkerboard with red dot and occasional green dot. Blood-oxygen-level-dependent (BOLD) fMRI was analyzed using statistical parametric mapping and DTI on NordicIce (NordicNeuroLab) softwares. Reduced occipital activation was elicited when viewing with the amblyopic eye in amblyopes. An 'ipsilateral to viewing eye' pattern of calcarine BOLD activation was observed in controls and left amblyopes. Activation of cortical areas associated with visual processing differed in relation to the viewing eye. Following visual recovery on occlusion therapy, enhanced activity in bilateral hemispheres in striate as well as extrastriate regions when viewing with either eye was seen. Improvement in visual acuity following occlusion therapy correlates with hemodynamic activity in amblyopes.
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Gupta S,Kumaran SS,Saxena R,Gudwani S,Menon V,Sharma Pdoi
10.1007/s10792-015-0159-2subject
Has Abstractpub_date
2016-08-01 00:00:00pages
557-68issue
4eissn
0165-5701issn
1573-2630pii
10.1007/s10792-015-0159-2journal_volume
36pub_type
杂志文章abstract:OBJECTIVE:To assess the comprehensive effects of raloxifene hydrochloride on retinal, choroidal and retrobulbar hemodynamics and on visual function in post-menopausal women. DESIGN:Twenty-four post-menopausal women (age 55 +/- 3.8 years) were recruited for this cross-sectional study: 12 received placebo and 12 receive...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1007/s10792-008-9224-4
更新日期:2009-08-01 00:00:00
abstract::Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus ...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-008-9223-5
更新日期:2008-06-01 00:00:00
abstract::Ocular tuberculosis is difficult to diagnose but should be suspected when uveitis fails to respond to inflammation suppressive therapy. Interferon-gamma release assays (IGRAs) represent a substantial help to diagnose suspected ocular tuberculosis especially in non-endemic areas. Indocyanine green angiography (ICGA) is...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-012-9588-3
更新日期:2012-10-01 00:00:00
abstract::Ectopic cilia are the most rare of cilial anomalies. We report a 27-year-old man who presents with tarsal conjunctival symptomatic ectopic cilia. On slit-lamp examination eversion of the lower eyelid demonstrated that several black-white cilia were protruding from the conjunctiva. ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9228-0
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:To evaluate the cognitive performance of patients with glaucoma and compare it to individuals with Alzheimer's disease (AD). METHODS:This is a prospective, cross-sectional and case-control study. All subjects were assessed using the Mini-Mental State Examination (MMSE) and its subtests verbal fluency, word lis...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-017-0658-4
更新日期:2018-10-01 00:00:00
abstract::Acute and invasive fungal infections are usually seen in immunocompromised and debilitated patients. We report a young immunocompetent 28-year-old Indian male who presented with unilateral endogenous endophthalmitis in the left eye and was managed with pars plana vitreous surgery. The polymerase chain reaction from th...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-008-9235-1
更新日期:2009-08-01 00:00:00
abstract::A case of orbital metastasis of cervical keratinizing squamous cell carcinoma is presented. The patient, in remission from primary cervical and ovarian cancers, presented with complaints of left eye ptosis and pain. Examination revealed the presence of a moderately tender mass along the left supra-temporal orbital rim...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-007-9162-6
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To investigate the dry eye symptoms after cataract surgery in MGD patients and their relationships METHODS: The study included 115 patients (115 eyes) with age-related cataract that underwent uncomplicated cataract surgery, and the patients were divided into two groups according to the MGD diagnostic criteria...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01294-8
更新日期:2020-05-01 00:00:00
abstract::The purpose of this study was to evaluate the impact of intravitreal bevacizumab injections on the management and outcome of patients affected by retinal vein occlusions, their effectiveness on morphological and functional parameters, the modalities of long-term management and the need for additional laser treatment d...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-0002-1
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To evaluate by Environmental Scanning Electron Microscopy (ESEM) the corneal incision architecture after intraocular lens (IOL) implantation in pig eyes, using manual, automated injectors or preloaded delivery systems. METHODS:Twenty-four pig eyes underwent IOL implantation in the anterior chamber using three ...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0825-2
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Oncocytoma is rarely found around the lacrimal punctum. We describe a case of oncocytoma of the peripunctum. METHODS:Case report. RESULTS:An 88-year-old patient presented with a upper peripunctal mass in the left eye. The tumor was completely excised including the lacrimal punctum and part of the canalicul...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-006-9008-7
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:To report a childhood case of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) carrying the R92Q variant with a vision-threatening bilateral panuveitis. METHODS:Case report and review of the literature. RESULTS:A 7-year-old boy presented with an active bilateral panuveitis and a macular ras...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-017-0785-y
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:Ripasudil accelerates aqueous humour drainage along the trabecular meshwork-Schlemm's canal route and has been approved for clinical use in Japan. We retrospectively investigated the efficacy and safety of adding ripasudil to existing treatment regimens to reduce intraocular pressure (IOP) in patients with glau...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-016-0427-9
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To compare capillaries perfusion in macular areas at different layers and peripapillary region in radial peripapillary capillaries (RPC) between healthy subjects and subjects with obstructive sleep apnea-hypopnea (OSA) using spectral-domain optical coherence tomography angiography (OCTA). METHODS:Totally 16 ey...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01518-x
更新日期:2020-12-01 00:00:00
abstract::To evaluate the efficacy of 25-ga pars plana vitrectomy (PPV) and 25-ga PPV combined with phacoemulsification surgery for managing ciliary block (malignant) glaucoma. The medical records of 11 eyes, in nine consecutive patients with malignant glaucoma were retrospectively reviewed to determine the efficacy of 25-ga PP...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-014-9974-0
更新日期:2015-08-01 00:00:00
abstract::The objective of this study is to evaluate the visual prognosis and postoperative course in advanced glaucoma patients who underwent trabeculectomy. The records of 30 patients with advanced visual field (VF) defects undergoing trabeculectomy were retrospectively reviewed. Severe VF defects were defined as those with a...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-011-9494-0
更新日期:2011-12-01 00:00:00
abstract::We report the functional outcome of a patient who had undergone Boston keratoprosthesis type I for extensive ocular surface damage caused by latex of Euphorbia. The milky sap or latex of the Euphorbia plant is highly toxic and an irritant to the skin and eye. Damage to the eye ranges from mild to severe corneal edema,...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-012-9515-7
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:The aim of this prospective study is to verify, in terms of both early postoperative complications and intraocular pressure (IOP) outcomes, the performance of a scleral flap removable suture. MATERIALS AND METHODS:Sixty-six patients that underwent trabeculectomy were randomly divided into two groups: in t...
journal_title:International ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10792-008-9245-z
更新日期:2009-10-01 00:00:00
abstract::To document the rate of self-reported compliance and glaucoma-related knowledge in Swiss patients and to identify risk factors for their poor compliance. This was an observational study, including a total of 200 consecutive patients already under glaucoma medication in two Swiss tertiary glaucoma clinics (Geneva and B...
journal_title:International ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10792-011-9468-2
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:Regional variations of the preoperative biometry can affect the refractive accuracy of cataract surgery. We aimed to compare the preoperative biometric data for cataract surgery between two domestic institutions. METHODS:We retrospectively reviewed the preoperative biometric data of 673 consecutive eyes underg...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01476-4
更新日期:2020-11-01 00:00:00
abstract::It is unclear whether epipolis-laser in situ keratomileusis (Epi-LASIK) has any significant advantage over photorefractive keratectomy (PRK) for correcting myopia. We undertook this meta-analysis of randomized controlled trials and cohort studies to examine possible differences in efficacy, predictability, and side ef...
journal_title:International ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10792-015-0109-z
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:The aim of the present study was to prospectively examine the effect of two styles of PRP, full- and mild-scatter on central and peripheral visual field in diabetic patients. METHODS:40 eyes with preproliferative or early proliferative diabetic retinopathy of 32 patients underwent visual field testing on the C...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006367029134
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To describe the incidence of, and risk factors associated with, diabetic retinopathy in diabetic persons assessed at a Saudi diabetes centre. METHODS:Five hundred and two patients with diabetes mellitus assessed by our service were studied. There were 174 patients (34.7%) with insulin-dependent diabetes mellit...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1023/a:1006240928938
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:The surgical management of macular holes has been a subject of controversy in recent years. Various techniques such as vitrectomy, membrane peeling, and gas tamponade with or without transforming growth factor-beta 2, and recently the use of autologous platelets have produced closure rates from 58% to 96%, d...
journal_title:International ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1023/a:1005866002930
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:Primary ocular adnexal lymphomas are cured by radiotherapy; however, complications are frequent and relapses may occur. In this case, we aimed to report the efficacy and safety of extended systemic rituximab (anti-CD 20 monoclonal antibody) therapy of conjunctival mucosa-associated lymphoid tissue (MALT) lympho...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-018-0844-z
更新日期:2019-03-01 00:00:00
abstract::This paper builds on results of a previous paper on the prevalence of trachomatous visual impairment as the foundation for assessing the global burden of trachomatous blindness and low vision: approximately 2.9 million cases of trachomatous blindness and 3.8 million low visioned corresponding to a global prevalence of...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00130921
更新日期:1995-01-01 00:00:00
abstract::The ocular surface is exposed to many chronic inflammatory stimuli, and goblet cell hyperplasia of the conjunctiva occurs in many situations. We report two cases of epithelial goblet cell hyperplasia with nonspecific chronic inflammation which occurred on the internal canthus of elderly people. These cases shared the ...
journal_title:International ophthalmology
pub_type: 杂志文章,评审
doi:10.1007/s10792-015-0083-5
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) refers to the detachment of the ciliary body and choroid from the sclera along with retinal detachment. The recovery of visual function is often far worse after surgical treatment of RRDCD than following anatomical reduction for c...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01433-1
更新日期:2020-10-01 00:00:00
abstract::The cases of 23 patients with unilateral combined central retinal artery-central retinal vein obstruction are described. Criteria for the abnormality included: a history of relatively sudden visual loss; superficial retinal whitening in the posterior pole in combination with a cherry spot; and intraretinal blood, gene...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/BF00918861
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:To evaluate the preliminary effects of treating the half of high latent hyperopia on refractive and visual outcomes of femtosecond laser-assisted in situ keratomileusis (LASIK) in young subjects with hyperopia. METHODS:This non-randomized comparative study includes 120 eyes of 60 subjects who underwent femt...
journal_title:International ophthalmology
pub_type: 杂志文章
doi:10.1007/s10792-020-01421-5
更新日期:2020-09-01 00:00:00