Progression of gyrate atrophy measured with ultra-wide-field imaging.

Abstract:

:The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and follow-up. Measurements of atrophy were obtained for three types of lesions: Solitary atrophic lesions (SAL), De novo solitary lesions (DNSL), and peripapillary atrophy (PPA). Comparison of baseline and follow-up was done using t tests. Two patients with gyrate atrophy were included. Patient 1 presented 16 SAL, 5 DNSL, and PPA measured for both eyes (BE). Overall area growth (OAG) for SAL (expressed in decimals) presented a mean of 3.41, σ 3.07. DNSL area for BE presented a mean of 1586.08 P (2), σ 1069.55. OAG for PPA presented a mean of 1.21, σ 0.17. Patient 2 presented 5 SAL, no DNSL, and PPA was measured for BE. OAG for SAL presented a mean of 1.58, σ 1.05 (range 1.02-3.47). OAG for PPA presented a mean of 1.05, σ 0.001. Gyrate atrophy progression can be determined by measuring the changes in area using UWFI.

journal_name

Int Ophthalmol

authors

Salcedo-Villanueva G,Paciuc-Beja M,Villanueva-Mendoza C,Harasawa M,Smith JM,Velez-Montoya R,Olson JL,Oliver SC,Mandava N,Quiroz-Mercado H

doi

10.1007/s10792-015-0085-3

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

111-120

issue

1

eissn

0165-5701

issn

1573-2630

pii

10.1007/s10792-015-0085-3

journal_volume

36

pub_type

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