Abstract：
PURPOSE:To determine the efficacy of locally produced Latanoprost in reducing the intraocular pressure (IOP) in patients with Primary open-angle glaucoma (POAG). DESIGN:Open-label, non-comparative, observational case study with non-probability purposive sampling. METHODS:A total of 48 patients (94 eyes) of either gender were recruited from glaucoma clinic with the diagnosis of POAG, having IOP of more than 21 mmHg. Patients were commenced on locally produced Latanoprost (Vislat 0.005%). IOP was subsequently measured at 4 weeks and 12 weeks, respectively. The primary end point was reduction in IOP at 12 weeks after the initiation of treatment. RESULTS:A total of 48 patients (94 eyes) were recruited from glaucoma clinic. The average IOP of our patients at baseline was 28.6 ± 8.1 mmHg, decreasing to 21.3 ± 10.6 mmHg at 4 weeks, indicating a drop of 19.1% (P < 0.001). IOP further decreased to 20.3 ± 8.7 mmHg after 3 months of treatment indicating a decrease of 23.3% (P < 0.001). A decrease in IOP occurred in 51 eyes (71.8%) at 4 weeks after treatment, improving to 54 eyes (76%) at 3-month follow-up. Twenty eyes (28.1%) did not show any change in IOP at 4 weeks. However, after 3-month follow-up only 17 eyes (23.9%) did not reveal any change in IOP. CONCLUSION:Our results showed a decrease in IOP of 19.1% after 4 weeks, increasing to 23.3% at 12 weeks in cohort of 37 patients (72 eyes) treated with locally produced Latanoprost (Vislat 0.005%).
journal_name
Int Ophthalmoljournal_title
International ophthalmologyauthors
Mahar PS,Butt NH,Ali SIdoi
10.1007/s10792-017-0773-2subject
Has Abstractpub_date
2018-12-01 00:00:00pages
2593-2597issue
6eissn
0165-5701issn
1573-2630pii
10.1007/s10792-017-0773-2journal_volume
38pub_type
杂志文章,多中心研究abstract：:To investigate subconjunctival bevacizumab as an adjuvant in first-time glaucoma filtration surgery, we conducted a non-comparative, interventional case series, enrolling consecutive patients with uncontrolled primary glaucomas. All patients underwent trabeculectomy with mitomycin C and received a 1.25 mg subconjuncti...
journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/s10792-012-9704-4
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To report a case of resolution of retinal arterial aneurysms in a patient of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) treated with oral steroids. METHODS:This study contains case report and review of literature. RESULTS:A 16-year-old girl with stage 2 IRVAN was treated with oral ste...
journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0913-3
更新日期：2019-05-01 00:00:00
abstract：:Dear editor and readers, this letter is written to make you aware that the original version of this article unfortunately contained a mistake. ...
journal_title：International ophthalmology
pub_type： 杂志文章,已发布勘误
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abstract：:Knowledge of the presentation pattern of glaucoma helps in providing more understanding of the disease, leading to better control. The aim of this study was to determine the presentation pattern among newly diagnosed glaucoma patients in Lagos, Nigeria. This was a multicenter cross-sectional survey of newly diagnosed ...
journal_title：International ophthalmology
pub_type： 杂志文章,多中心研究
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journal_title：International ophthalmology
pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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journal_title：International ophthalmology
pub_type： 杂志文章
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journal_title：International ophthalmology
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：1987-10-01 00:00:00
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更新日期：2012-10-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00128955
更新日期：1991-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00133274
更新日期：1978-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,评审
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：2013-02-01 00:00:00
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pub_type： 杂志文章
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00159862
更新日期：1990-07-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
doi：10.1007/BF00136495
更新日期：1985-09-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章,评审
doi：10.1007/s10792-018-0984-1
更新日期：2019-07-01 00:00:00
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journal_title：International ophthalmology
pub_type： 杂志文章
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更新日期：1995-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2010-08-01 00:00:00
