Abstract:
:Living organisms undergo biochemical, physiological and behavioral cycles with periods ranging from seconds to years. Cycles with intermediate periods are governed by endogenous clocks that depend on oscillating gene expression. Here we illustrate the modalities and specific functions of post-transcriptional control of gene expression (exerted on pre-mRNAs and mRNAs) in biological clocks through two examples: the circadian clock and the vertebrate somite segmentation clock, an embryonic clock with a period far below a day. We conclude that both constitutive and cyclic post-transcriptional controls underpin clock function.
journal_name
Trends Cell Bioljournal_title
Trends in cell biologyauthors
Cibois M,Gautier-Courteille C,Legagneux V,Paillard Ldoi
10.1016/j.tcb.2010.06.004subject
Has Abstractpub_date
2010-09-01 00:00:00pages
533-41issue
9eissn
0962-8924issn
1879-3088pii
S0962-8924(10)00119-4journal_volume
20pub_type
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