Abstract:
:The efficacy of ofloxacin for the treatment of lower respiratory tract infection was evaluated in aged patients with chronic lung disease. Results are the following: improvement of leukocytosis and arterial oxygen tension was observed; peripheral blood cell analysis showed a decrease in natural killer cell counts and in helper/suppressor T cell ratio; superoxide production by peripheral blood white cells was decreased after treatment; interleukin-2 production was rather increased. We concluded that improvement in the immunological parameters indicated the efficacy of ofloxacin for lower respiratory tract infection in aged patients with chronic lung disease.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Yamaoka M,Fukuchi Y,Yokouchi M,Teramoto N,Nagase T,Ishida K,Ohtomo E,Orimo Hdoi
10.1159/000238901subject
Has Abstractpub_date
1991-01-01 00:00:00pages
14-8eissn
0009-3157issn
1421-9794journal_volume
37 Suppl 1pub_type
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