Abstract:
:Crl:CD1(ICR) BR mice were fed chow containing Candida albicans or regular chow. Both groups were subsequently given either antibiotics or normal saline. Stool cultures were performed before, at the end of treatment and 1 week after treatment, to determine the effect on the stool yeast concentration. Candida-colonized mice treated with cefepime, cefixime or ceftibuten had higher (however not significantly) counts of the yeast in their stools than control Candida-fed mice treated with saline. A group of Candida-fed mice were treated with ceftriaxone, which is known to increase the yeast stool concentration significantly and served as positive control. Mice fed regular chow and treated with the study drugs or saline did not have any yeasts in their stools. Dissemination of Candida did not occur.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Maraki S,Barbounakis E,Chatzinikolaou I,Anatoliotakis N,Plataki M,Tselentis Y,Samonis Gdoi
10.1159/000007151subject
Has Abstractpub_date
1998-11-01 00:00:00pages
405-8issue
6eissn
0009-3157issn
1421-9794pii
che44405journal_volume
44pub_type
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