Abstract:
:The effect of acyclovir (ACV) treatment on selected functions of human blood-derived macrophages was examined. ACV was not cytotoxic when applied in a wide range of concentrations. Only minor effects on macrophage functions were observed when cells were treated with therapeutic concentrations of ACV:phagocytosis and the production of interferon and tumor necrosis factor were slightly enhanced, while the production of lysozyme was reduced, in a dose-dependent manner. Interferon production was also reduced in the presence of high concentrations of ACV.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Stenseth AM,Rollag H,Degré Mdoi
10.1159/000239126subject
Has Abstractpub_date
1993-05-01 00:00:00pages
197-202issue
3eissn
0009-3157issn
1421-9794journal_volume
39pub_type
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