The value of tumor markers in evaluating chemotherapy response and prognosis in Chinese patients with advanced non-small cell lung cancer.

abstract：:Despite extensive research efforts, effective therapies for refractive cancers have not yet been established, and development of successful treatment strategies remains the most important task in the field of oncology. We recently showed that AVE8062 (formerly AC7700), a derivative of combretastatin A-4, achieved irre...

journal_title：Chemotherapy

authors： Hori K

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Levofloxacin and tobramycin, alone and in combination with cefepime, were investigated for their in vitro activities and post-antibiotic effects (PAEs) on Pseudomonas aeruginosa. METHODS:The in vitro activities of tobramycin and levofloxacin in combination with cefepime were determined by microbroth chequer...

journal_title：Chemotherapy

authors： Ozbek B,Otuk G

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Very little is documented in the medical literature on the association between malaria parasitemia and febrile neutropenia in patients undergoing cancer chemotherapy. METHODS:This report will concentrate on the clinical presentation and outcome of 3 patients with haematological malignancies undergoing chemo...

journal_title：Chemotherapy

authors： Rapoport BL,Uys A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate the impact of different temperatures (22, 35 and 37 degrees C) on the postantifungal effect (PAFE) and the effect of sub-MIC concentrations (1/4 x MIC) on Candida albicans and Candida glabrata in PAFE stage (PAFSE). METHODS:This stage was induced by a 1.5-hour ...

journal_title：Chemotherapy

authors： García MT,Llorente MT,Mínguez F,Prieto J

更新日期：2000-07-01 00:00:00

abstract：:Concentrations of cefotetan in the intestinal wall of patients with Crohn's disease were investigated with the method of tissue homogenates with the aim to evaluate the effects of inflammation on tissue distribution. Twenty-four patients who underwent surgery were treated with a 2-gram single dose of cefotetan intrave...

journal_title：Chemotherapy

authors： Mazzei T,Tonelli F,Anastasi A,Ficari F,Novelli A,Periti P

更新日期：1991-01-01 00:00:00

abstract：:The comparative in vitro activity of amikacin, cefamandole, cefoperazone, cefotaxime, cefoxitin, cephalothin, chloramphenicol, moxalactam, piperacillin, ticarcillin and tobramycin against 170 community blood culture isolates of gram-negative bacilli was investigated using the quantitative plate dilution method. Result...

journal_title：Chemotherapy

authors： Gordon RC,Tack KJ,Haddy RI,Fechner L,Wofford R

更新日期：1984-01-01 00:00:00

abstract：:Thirteen quinolone antibacterial agents were investigated as to their ability to inhibit Micrococcus luteus DNA gyrase and cell growth, and compared to those of novobiocin and coumermycin. Among the quinolones tested, the most active were found to be CI-934 and ciprofloxacin, which inhibited gyrase full supercoiling a...

journal_title：Chemotherapy

authors： Fu KP,Grace ME,McCloud SJ,Gregory FJ,Hung PP

更新日期：1986-01-01 00:00:00

abstract：:One patient of sepsis by P. aeruginosa after the implanting of a ventriculoatrial valve following extirpation of an expansive intracranial process is studied. During the evolution of the septic process there appeared as associated nephrotic syndrome with histologic lesions corresponding to an acute exudative glomerula...

journal_title：Chemotherapy

authors： Rodriguéz-Gironés M,Genovés A

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the antimicrobial susceptibility patterns among common pathogens in the intensive care unit (ICU) of a university hospital in Iran between 2006 and 2009. METHODS:The isolates cultured in appropriate media and antimicrobial susceptibility were determined by disk diffusio...

journal_title：Chemotherapy

authors： Mohammadtaheri Z,Pourpaki M,Mohammadi F,Namdar R,Masjedi MR

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Development of novel strategies to kill cancer by sparing normal cells is of utmost importance. Apart from their known antimicrobial activity, only limited information has been recorded regarding the antitumor potential of biocompatible silver oxide nanoparticles (AgONPs). There is a need to evaluate the ant...

journal_title：Chemotherapy

authors： Banerjee K,Das S,Choudhury P,Ghosh S,Baral R,Choudhuri SK

更新日期：2017-01-01 00:00:00

abstract：:The influence of normal human serum on bactericidal activity of ceftizoxime sodium (CZX) was studied in vitro against Escherichia coli and Staphylococcus aureus. Subminimal inhibitory concentrations of CZX inhibited the growth of bacteria. Normal human serum as a source of complement and low doses of CZX, such as 1/20...

journal_title：Chemotherapy

authors： Watanabe K,Kin R,Murakami M,Kondo M

更新日期：1986-01-01 00:00:00

abstract：:Cefepime is active against bacteria producing chromosomally and plasmid-mediated extended broad-spectrum β-lactamase enzymes. The aim of this study was to evaluate risk factors for acquisition of cefepime resistance in Escherichia coli strains among hospitalized patients in a university hospital in Sanandaj, Iran. The...

journal_title：Chemotherapy

authors： Mansouri M,Ramazanzadeh R,Norabadi P

更新日期：2011-01-01 00:00:00

abstract：:An agar dilution technique was used to determine the MIC of pristinamycin for 124 clinical isolates of methicillin-resistant Staphylococcus aureus. All were inhibited by less than or equal to 0.5 mg/1, quite similar to the sensitivity of a number of methicillin-sensitive strains. MICs obtained using a microdilution me...

journal_title：Chemotherapy

authors： Mutton KJ,Andrew JH

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The discovery of mutations in epidermal growth factor receptor (EGFR) has dramatically changed the treatment of patients with non-small-cell lung cancer (NSCLC), the leading cause of cancer deaths worldwide. EGFR-targeted therapies show considerable promise, but drug resistance has become a substantial issue...

journal_title：Chemotherapy

authors： Tetsu O,Hangauer MJ,Phuchareon J,Eisele DW,McCormick F

更新日期：2016-01-01 00:00:00

abstract：:The biliary excretion of tetroxoprim (TXP) was studied in 10 patients with T-tube drainage. A mean biliary peak of 32.56 +/- 7.69 micrograms/ml was observed 2-3 h after a single oral dose of 200 mg. The biliary elimination rate constant (kb) of TXP was found to be 0;056 (h-1), indicating a longer elimination from the ...

journal_title：Chemotherapy

authors： Vergin H,Luber P

更新日期：1982-01-01 00:00:00

abstract：:In this paper the bactericidal activities of ofloxacin and its optically active derivative, DR-3355, against non-growing cells of Escherichia coli and Pseudomonas aeruginosa are described. E. coli and P. aeruginosa were killed rapidly by ofloxacin and DR-3355. After treatment with these quinolones, the resting cells o...

journal_title：Chemotherapy

authors： Tanaka M,Otsuki M,Nishino T

更新日期：1992-01-01 00:00:00

abstract：:A narcissus alkaloid, pretazettine hydrochloride (PTZ), has been shown to be active against Ehrlich ascites carcinoma. The Ehrlich cells are more sensitive to PTZ in DBA/2 mice than in Swiss mice. The therapeutic activity of the individual standard drugs in ABC (adriamycin, BCNU, and cyclophosphamide) regimen against ...

journal_title：Chemotherapy

authors： Furusawa E,Lum MK,Furusawa S

更新日期：1981-01-01 00:00:00

abstract：:The cellular/extracellular (C/E) concentration ratio of teicoplanin in polymorphonuclear leukocytes (PMNs) increased rapidly with time (C/E 60 +/- 13 at 20 min). The C/E ratio was time- and concentration-dependent. At 20 min and an initial concentration of 75 +/- 16 micrograms/ml the cellular drug concentration was 4,...

journal_title：Chemotherapy

authors： Maderazo EG,Breaux SP,Woronick CL,Quintiliani R,Nightingale CH

更新日期：1988-01-01 00:00:00

abstract：:A multicenter study aimed at assessing the in vitro activity of sulbactam/ampicillin against a wide range of bacterial pathogens was performed using 2,209 clinical strains, all recently collected from inpatients in seven Italian centers and preliminarily screened as being ampicillin-resistant and beta-lactamase produc...

journal_title：Chemotherapy

authors： Varaldo PE,Ripa S,Nicoletti G,Covelli I,Satta G,Carlone N,Fontana R

更新日期：1990-01-01 00:00:00

abstract：:Itraconazole has emerged as an important new oral agent in the treatment of systemic fungal infections. This paper summarizes the data available on its use in aspergillosis, cryptococcosis and histoplasmosis, compiled in the United States with particular attention to the immunocompromised host. Data have been accrued ...

journal_title：Chemotherapy

authors： Hostetler JS,Denning DW,Stevens DA

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Taxanes cause hypersensitivity reactions, averted by premedication with H1 blockers and high glucocorticoid (GC) doses. Prolonged weekly taxane administration may lead to GC toxicity. PURPOSE:To determine whether patients not hypersensitive to initial paclitaxel (PTX) infusion after high-dose GC premedicati...

journal_title：Chemotherapy

authors： Braverman AS,Rao S,Salvatti ME,Adamson B,McManus M,Pierre S

更新日期：2005-05-01 00:00:00

abstract：:Phase contrast microscopy, killing curves and turbidimetric growth curves were used in a comparative study of the antibacterial effects of imipenem and meropenem on Haemophilus influenzae. The minimal inhibitory concentrations (MICs) and their ranges of meropenem and imipenem using five beta-lactamase-producing strain...

journal_title：Chemotherapy

authors： Yourassowsky E,Van der Linden MP,Crokaert F

更新日期：1991-01-01 00:00:00

abstract：:The frustration and disappointment in managing advanced cancers of the nose and paranasal sinuses are well known. We report a case of a successful treatment of such a tumour in a 37-year-old soldier, using a combination of therapy including surgery, chemotherapy and radiation. Each mode of treatment is discussed. ...

journal_title：Chemotherapy

authors： Chandrasekaran S,Baba AA,Othman N,Jayakumar CR

更新日期：1994-09-01 00:00:00

abstract：:The effect of tinidazole on several ciliates (Stylonychia muscorum, Stylonychia mytilus, Tetrahymena pyriformis, Vorticella companula) has been studied. There is a very pronounced difference in sensitivity against this drug between the free-living ciliates here investigated and certain parasitic protozoa. A high resis...

journal_title：Chemotherapy

authors： Alonso P

更新日期：1979-01-01 00:00:00

abstract：:The effects of the sub-MIC of antibiotics on the surface hydrophobicity and charge of Staphylococcus aureus were examined by the contact angle method and by microscopic electrophoresis, and the production of oxygen-derived radicals by mouse peritoneal macrophages was measured by a luminol-chemiluminescence assay. The ...

journal_title：Chemotherapy

authors： Nomura S,Kuroiwa A,Nagayama A

更新日期：1995-03-01 00:00:00

abstract：:A method is described which may be used to compare the relative activity of beta-lactam antibiotics against gram-negative bacilli. The method offers several important advantages over conventional methods of evaluation of the antibacterial activity of beta-lactam agents: the bacterial inoculum is simply and accurately ...

journal_title：Chemotherapy

authors： Greenwood D

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:In this study (part of the global TEST program), the in vitro activity of tigecycline, a member of a new class of antimicrobial agents, the glycylcyclines, against clinical isolates collected in Italy was evaluated. METHODS:A total of 200 clinical isolates were collected and identified in our institution du...

journal_title：Chemotherapy

authors： Roveta S,Marchese A,Debbia EA

更新日期：2008-01-01 00:00:00

abstract：:100 febrile patients with chemotherapy-induced neutropenia (less than 0.5 x 10(9)/l) were empirically treated by ceftriaxone (2 g daily in adults, 50 mg/kg daily in children, as a once daily injection) and amikacin (15-20 mg/kg daily). The mean age was 41 years (range 8-72). 51 patients had acute leukemia, 29 non-Hodg...

journal_title：Chemotherapy

authors： Blanc C,Pollet JP,Bauters F

更新日期：1991-01-01 00:00:00

abstract：:Pyrazinamide (PZA) is an unconventional frontline tuberculosis drug characterized by high in vivo sterilizing activity, but poor in vitro activity. The study on the mechanism of action of PZA has attracted significant attention because of the peculiarity of PZA and its ability to shorten the tuberculosis chemotherapy....

journal_title：Chemotherapy

authors： Huang Q,Chen ZF,Li YY,Zhang Y,Ren Y,Fu Z,Xu SQ

更新日期：2007-01-01 00:00:00

abstract：:The effects of cis-[Pt(NH3)2Cl2] on the spontaneous cell-mediated cytotoxicity of human lymphoblast cell lines mediated by normal human peripheral blood lymphocytes was investigated. Direct addition of cis-[Pt(NH3)2Cl2], but not its tumor inactive trans isomer, to the in vitro spontaneous cytotoxicity assay resulted i...

journal_title：Chemotherapy

authors： Mally MB,Taylor RC,Callewaert DM

更新日期：1980-01-01 00:00:00