Abstract:
BACKGROUND:Very little is documented in the medical literature on the association between malaria parasitemia and febrile neutropenia in patients undergoing cancer chemotherapy. METHODS:This report will concentrate on the clinical presentation and outcome of 3 patients with haematological malignancies undergoing chemotherapy who developed febrile neutropenia and malaria parasitemia concurrently. RESULTS:Three patients infected with documented malaria during a febrile neutropenic episode are presented. Two patients (1 with Hodgkin's disease and the other with non-Hodgkin's lymphoma) were successfully treated and are alive after a follow-up period of 120 and 90 months, respectively. A third patient with acute lymphoblastic leukaemia developed renal failure as a complicating factor of malaria and died. CONCLUSION:It is suggested that malaria should be considered as a possible cause or a complicating factor of febrile neutropenia in patients undergoing cancer chemotherapy in endemic malaria areas.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Rapoport BL,Uys Adoi
10.1159/000118663subject
Has Abstractpub_date
2008-01-01 00:00:00pages
117-9issue
2eissn
0009-3157issn
1421-9794pii
000118663journal_volume
54pub_type
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