Abstract：
:Plant defensins are a prominent family of cationic peptides in the plant kingdom. They are structurally and functionally related to defensins that have been previously characterized in mammals and insects. They present molecular masses between 5 and 7kDa and possess a pattern of eight conserved Cys residues. The three-dimensional structure of plant defensins is small and globular. It has three anti-parallel beta-sheets and one alpha-helix that is stabilized by a structural motif composed of disulfide bridges. This motif is found in other peptides with biological activity and is called the Cys stabilized alphabeta motif (CSalphabeta). Based on the growing knowledge on defensin structure, gene expression and regulation, and also their in vitro biological activity, it has become clear that plant defensins are complex and sophisticated peptides whose function extends beyond their role in defense of plants against microbial infection. This review discusses recent data and will present comprehensive information regarding the study of defensins.
journal_name
Peptidesjournal_title
Peptidesauthors
Carvalho Ade O,Gomes VMdoi
10.1016/j.peptides.2009.01.018subject
Has Abstractpub_date
2009-05-01 00:00:00pages
1007-20issue
5eissn
0196-9781issn
1873-5169pii
S0196-9781(09)00045-Xjournal_volume
30pub_type
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