Abstract:
:The dopaminergic D3 receptor (D3R) is emerging as an antagonist of sensitized behavior induced by addictive drugs such as cocaine. New work by Wang and coworkers in this issue of Neuron now identifies CaMKII as an important negative regulator of the D3R. CaMKII relieves the D3R-mediated inhibition on sensitized behavior to foster drug-seeking behavior.
journal_name
Neuronjournal_title
Neuronauthors
Hell JWdoi
10.1016/j.neuron.2009.01.025subject
Has Abstractpub_date
2009-02-12 00:00:00pages
335-6issue
3eissn
0896-6273issn
1097-4199pii
S0896-6273(09)00092-0journal_volume
61pub_type
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