Undercover Power of Endocannabinoids: Postsynaptic Ion-Channel Modulator.

Abstract:

:In this issue of Neuron, Gantz and Bean (2017) show that the endocannabinoid 2-arachidonoyl glycerol (2-AG) can directly alter the properties of native ion-channel Kv4.3 and accelerate the pacemaker activity of rodent dopamine neurons. These findings are one of the first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoids in the mammalian brain.

journal_name

Neuron

journal_title

Neuron

authors

Matsui A,Alvarez VA

doi

10.1016/j.neuron.2017.03.014

subject

Has Abstract

pub_date

2017-03-22 00:00:00

pages

1243-1244

issue

6

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(17)30197-6

journal_volume

93

pub_type

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