Abstract:
:Circadian clock proteins are modified in many different ways. The best-studied posttranslational modification is phosphorylation, with well-known kinases and phosphatases regulating the function and stability of clock proteins. Degradation of these proteins usually involves ubiquitylation or sumoylation, and some of the relevant E3 ligases are known. In addition, Hirayama et al. recently identified acetylation as a clock regulatory mechanism.
journal_name
Neuronjournal_title
Neuronauthors
Sehgal Adoi
10.1016/j.neuron.2007.12.018subject
Has Abstractpub_date
2008-01-10 00:00:00pages
8-10issue
1eissn
0896-6273issn
1097-4199pii
S0896-6273(07)01028-8journal_volume
57pub_type
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