Abstract:
:Simple decisions arise from the evaluation of sensory evidence. But decisions are determined by more than just evidence. Individuals establish internal decision criteria that influence how they respond. Where or how decision criteria are established in the brain remains poorly understood. Here, we show that neuronal activity in the superior colliculus (SC) predicts changes in decision criteria. Using a novel "Yes-No" task that isolates changes in decision criterion from changes in decision sensitivity, and computing neuronal measures of sensitivity and criterion, we find that SC neuronal activity correlates with the decision criterion regardless of the location of the choice report. We also show that electrical manipulation of activity within the SC produces changes in decisions consistent with changes in decision criteria and are largely independent of the choice report location. Our correlational and causal results together provide strong evidence that SC activity signals the position of a decision criterion. VIDEO ABSTRACT.
journal_name
Neuronjournal_title
Neuronauthors
Crapse TB,Lau H,Basso MAdoi
10.1016/j.neuron.2017.12.006subject
Has Abstractpub_date
2018-01-03 00:00:00pages
181-194.e6issue
1eissn
0896-6273issn
1097-4199pii
S0896-6273(17)31129-7journal_volume
97pub_type
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