Immunoglobulin-like domains on bacteriophage: weapons of modest damage?

abstract：:The Saccharomyces cerevisiae genome sequence, augmented by new data on gene expression and function, continues to yield new findings about eukaryote genome evolution. Analysis of the duplicate gene pairs formed by whole-genome duplication indicates that selection for increased levels of gene expression was a significa...

journal_title：Current opinion in microbiology

authors： Seoighe C,Wolfe KH

更新日期：1999-10-01 00:00:00

abstract：:The environment is suffused with nearly countless types of fungi, and our immune systems must be tuned to cope with constant exposure to them. In addition, it is becoming increasingly clear that many surfaces of our bodies are colonized with complex populations of fungi (the mycobiome) in the same way that they are co...

journal_title：Current opinion in microbiology

authors： Iliev ID,Underhill DM

更新日期：2013-06-01 00:00:00

abstract：:In Myxococcus xanthus morphogenetic cell movements constitute the basis for the formation of spreading vegetative colonies and fruiting bodies in starving cells. M. xanthus cells move by gliding and gliding motility depends on two polarly localized engines, type IV pili pull cells forward, and slime extruding nozzle-l...

journal_title：Current opinion in microbiology

authors： Søgaard-Andersen L

更新日期：2004-12-01 00:00:00

abstract：:Translation of the genome into the proteome is a highly accurate biological process. However, the molecular mechanisms involved in protein synthesis are not error free and downstream protein quality control systems are needed to counteract the negative effects of translational errors (mistranslation) on proteome and c...

journal_title：Current opinion in microbiology

authors： Moura GR,Carreto LC,Santos MA

更新日期：2009-12-01 00:00:00

abstract：:Signal termination in two-component systems occurs by loss of the phosphoryl group from the response regulator protein. This review explores our current understanding of the structures, catalytic mechanisms and means of regulation of the known families of phosphatases that catalyze response regulator dephosphorylation...

journal_title：Current opinion in microbiology

authors： Silversmith RE

更新日期：2010-04-01 00:00:00

abstract：:Bacterial cell division takes place almost entirely below the diffraction limit of light microscopy, making super-resolution microscopy ideally suited to interrogating this process. I review how super-resolution microscopy has advanced our understanding of bacterial cell division. I discuss the mechanistic implication...

journal_title：Current opinion in microbiology

authors： Holden S

更新日期：2018-06-01 00:00:00

abstract：:The ongoing development of metagenomic approaches is providing the means to explore antibiotic resistance in nature and address questions that could not be answered previously with conventional culture-based strategies. The number of available environmental metagenomic sequence datasets is rapidly expanding and hencef...

journal_title：Current opinion in microbiology

authors： Monier JM,Demanèche S,Delmont TO,Mathieu A,Vogel TM,Simonet P

更新日期：2011-06-01 00:00:00

abstract：:Streptococcus agalactiae (group B Streptococcus, GBS), a normal constituent of the intestinal microbiota is the major cause of human neonatal infections and a worldwide spread 'hypervirulent' clone, GBS ST-17, is strongly associated with neonatal meningitis. Adhesion to epithelial and endothelial cells constitutes a k...

journal_title：Current opinion in microbiology

authors： Tazi A,Bellais S,Tardieux I,Dramsi S,Trieu-Cuot P,Poyart C

更新日期：2012-02-01 00:00:00

abstract：:Ustilago maydis is a well-established model system for biotrophic fungal plant pathogens. The fungus has a dimorphic life cycle with a yeast-like saprophytic phase switching to filamentous, pathogenic growth upon hyphal fusion. Due to its highly differentiated development and the amenability for reverse-genetics U. ma...

journal_title：Current opinion in microbiology

authors： Matei A,Doehlemann G

更新日期：2016-12-01 00:00:00

abstract：:Fluency in a common language allows individuals to convey information and carry out complex activities that otherwise would be difficult or even impossible without the benefit of shared communication. Cyclic (di)nucleotides have recently been recognized as such an accessible language understood by both microbe and the...

journal_title：Current opinion in microbiology

authors： Gao J,Tao J,Liang W,Jiang Z

更新日期：2016-04-01 00:00:00

abstract：:The enzymological and genetic aspects of microbial metabolism of hydrocarbons have been extensively revealed. Such molecular information is useful for understanding the bioremediation of oil spill environments and production of hydrocarbon-specific fine chemicals. ...

journal_title：Current opinion in microbiology

authors： Ishige T,Tani A,Sakai Y,Kato N

更新日期：2003-06-01 00:00:00

abstract：:Natural prokaryotic populations are composed of multiple clonal lineages that are different in their core genomes in a range that varies typically between 95 and 100% nucleotide identity. Each clonal lineage also carries a complement of not shared flexible genes that can be very large. The compounded flexible genome p...

journal_title：Current opinion in microbiology

authors： Rodriguez-Valera F,Martin-Cuadrado AB,López-Pérez M

更新日期：2016-06-01 00:00:00

abstract：:An understanding of the molecular bases of pathogenicity in Blastomyces dermatitidis and related systemic dimorphic fungi has been limited until recent years. Yeast cells of B. dermatitidis display an adhesion promoting protein termed WI-1. Recent studies entailing homologous gene targeting and mutation of WI-1 have p...

journal_title：Current opinion in microbiology

authors： Klein BS

更新日期：2000-08-01 00:00:00

abstract：:N(6)-methyl-adenines can serve as epigenetic signals for interactions between regulatory DNA sequences and regulatory proteins that control cellular functions, such as the initiation of chromosome replication or the expression of specific genes. Several of these genes encode master regulators of the bacterial cell cyc...

journal_title：Current opinion in microbiology

authors： Collier J

更新日期：2009-12-01 00:00:00

abstract：:Elimination of non-functional or unwanted proteins is critical for cell growth and regulation. In bacteria, ATP-dependent proteases target cytoplasmic proteins for degradation, contributing to both protein quality control and regulation of specific proteins, thus playing roles parallel to that of the proteasome in euk...

journal_title：Current opinion in microbiology

authors： Battesti A,Gottesman S

更新日期：2013-04-01 00:00:00

abstract：:Bacterium-host interactions are important for diverse ecological settings including pathogenicity and symbiosis. Electron cryotomography is a powerful method for studying the macromolecular complexes that mediate such interactions in situ. The main limitation of electron cryotomography is its restriction to relatively...

journal_title：Current opinion in microbiology

authors： Medeiros JM,Böck D,Pilhofer M

更新日期：2018-06-01 00:00:00

abstract：:Quorum sensing, or the control of gene expression in response to cell density, is used by both gram-negative and gram-positive bacteria to regulate a variety of physiological functions. In all cases, quorum sensing involves the production and detection of extracellular signalling molecules called autoinducers. While u...

journal_title：Current opinion in microbiology

authors： Bassler BL

更新日期：1999-12-01 00:00:00

abstract：:The human pathogenic Yersinia species cause diseases that represent a significant source of morbidity and mortality. Despite this, specific mechanisms underlying Yersinia pathogenesis and protective host responses remain poorly understood. Recent studies have shown that Yersinia disrupt cell death pathways, perturb in...

journal_title：Current opinion in microbiology

authors： Chung LK,Bliska JB

更新日期：2016-02-01 00:00:00

abstract：:Coxiella burnetii is a widespread zoonotic bacterial pathogen that causes human Q fever. In vivo, Coxiella displays a tropism for mononuclear phagocytes where it participates in biogenesis of a lysosome-like replication compartment to conduct its obligate intracellular lifestyle. Coxiella actively regulates multiple e...

journal_title：Current opinion in microbiology

authors： Voth DE,Heinzen RA

更新日期：2009-02-01 00:00:00

abstract：:Asexual sporulation (conidiation) in the ascomycetous filamentous fungi involves the formation of conidia, formed on specialized structures called conidiophores. Conidiation in filamentous fungi involves many common themes including spatial and temporal regulation of gene expression, specialized cellular differentiati...

journal_title：Current opinion in microbiology

authors： Park HS,Yu JH

更新日期：2012-12-01 00:00:00

abstract：:Bacterial shape has always been hypothesized to play an important role in the biology of a species and in the ability of certain bacteria to influence human health. The recent discovery of peptidoglycan hydrolases that modulate shape has now allowed this hypothesis to be addressed directly. Genetic, biochemical, and p...

journal_title：Current opinion in microbiology

authors： Frirdich E,Gaynor EC

更新日期：2013-12-01 00:00:00

abstract：:Recent studies have led to the identification of more than 50 small regulatory RNAs in Escherichia coli. Only a subset of these RNAs has been characterized. However, it is clear that many of the RNAs, such as the MicF, OxyS, DsrA, Spot42 and RyhB RNAs, act by basepairing to activate or repress translation or to destab...

journal_title：Current opinion in microbiology

authors： Storz G,Opdyke JA,Zhang A

更新日期：2004-04-01 00:00:00

abstract：:Infections caused by the apicomplexan parasites Plasmodium and Toxoplasma are wide-spread, life-threatening and therapeutically challenging. These pathogens are obligate intracellular microorganisms that invade mammalian cells by forming a self-made niche, the parasitophorous vacuole that is impervious to host lysosom...

journal_title：Current opinion in microbiology

authors： Coppens I

更新日期：2017-12-01 00:00:00

abstract：:Dictyostelium genome sequencing predicts an unexpectedly large number of genes. Many are absent from yeast but present in animals and presumably support cellular abilities not found in yeast. Prominent amongst these abilities is chemotaxis, where great strides are being made in understanding how cells orient in a grad...

journal_title：Current opinion in microbiology

authors： Kay RR

更新日期：2002-12-01 00:00:00

abstract：:Biofilm development and quorum sensing (QS) are closely interconnected processes. Biofilm formation is a cooperative group behaviour that involves bacterial populations living embedded in a self-produced extracellular matrix. QS is a cell-cell communication mechanism that synchronizes gene expression in response to po...

journal_title：Current opinion in microbiology

authors： Solano C,Echeverz M,Lasa I

更新日期：2014-04-01 00:00:00

abstract：:It is well accepted that bacterial pathogens growing in a biofilm are recalcitrant to the action of most antibiotics and are resistant to the innate immune system. New treatment modalities are greatly warranted to effectively eradicate these infections. However, bacteria growing in a biofilm are metabolically unique i...

journal_title：Current opinion in microbiology

authors： Fey PD

更新日期：2010-10-01 00:00:00

abstract：:Haloalkaliphiles are double extremophilic organisms thriving both at high salinity and alkaline pH. Although numerous haloalkaliphilic representatives have been identified among Archaea and Bacteria over the past 15 years, the adaptations underlying their prosperity at haloalkaline conditions are scarcely known. A mul...

journal_title：Current opinion in microbiology

authors： Banciu HL,Muntyan MS

更新日期：2015-06-01 00:00:00

abstract：:Most Candida albicans strains are heterozygous at the MTL (mating-type-like) locus, but mating occurs in hemi- or homozygous strains. The white-opaque switch process is repressed by the heterodimer of the MTLa1 and MTLalpha2 gene products, while mating genes are induced by a2 and alpha1. Mating occurs in opaque cells ...

journal_title：Current opinion in microbiology

authors： Magee PT,Magee BB

更新日期：2004-12-01 00:00:00

abstract：:The epithelial cell layer of the major organs of the mammalian gastrointestinal (GI) tract is extensively invaginated into thousands of gland and crypt structures. These are lined by distinct sets of epithelial cells and may comprise discrete niches. The host maximizes the distance between the epithelial cell layer an...

journal_title：Current opinion in microbiology

authors： Yang C,Ottemann KM

更新日期：2019-02-01 00:00:00

abstract：:Recent studies based on metagenomics and other molecular techniques have permitted a detailed knowledge of the microbial diversity and metabolic activities of microorganisms in hypersaline environments. The current accepted model of community structure in hypersaline environments is that the square archaeon Haloquadra...

journal_title：Current opinion in microbiology

authors： Ventosa A,de la Haba RR,Sánchez-Porro C,Papke RT

更新日期：2015-06-01 00:00:00