Chemotaxis and cell differentiation in Dictyostelium.

Abstract:

:Dictyostelium genome sequencing predicts an unexpectedly large number of genes. Many are absent from yeast but present in animals and presumably support cellular abilities not found in yeast. Prominent amongst these abilities is chemotaxis, where great strides are being made in understanding how cells orient in a gradient and mobilise their cytoskeleton for movement. In multicellular development, a regulatory scheme for proportioning prespore and prestalk-O cells has emerged.

journal_name

Curr Opin Microbiol

authors

Kay RR

doi

10.1016/s1369-5274(02)00375-2

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

575-9

issue

6

eissn

1369-5274

issn

1879-0364

pii

S1369527402003752

journal_volume

5

pub_type

杂志文章,评审
  • Microbial exposure and human health.

    abstract::The human body comprises of micro-ecosystem made up of trillions of microbes (i.e. bacteria, archaea, fungi, protists and viruses). The total microbial gene content, which is referred to as the human microbiome, is fundamental to human physiology and immunity. There exists an intricate relationship between the surroun...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2018.08.003

    authors: Sharma A,Gilbert JA

    更新日期:2018-08-01 00:00:00

  • The clinical consequences of antimicrobial resistance.

    abstract::The continued evolution of antimicrobial resistance in the hospital and more recently in the community threatens to seriously compromise our ability to treat serious infections. The major success of the seven-valent Streptococcus pneumoniae vaccine at reducing both infection and resistance has been followed by the eme...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2009.08.001

    authors: Rice LB

    更新日期:2009-10-01 00:00:00

  • Immune control of phagosomal bacteria by p47 GTPases.

    abstract::Sequestered from the action of complement, antibody and lytic peptides, phagosomal pathogens pose a unique problem for the innate immune system both in terms of detection and disposal. An immunologically induced 47-kDa (p47) GTPase family recruited to nascent phagosomes (PGs) has provided new insights into how vertebr...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2004.12.012

    authors: MacMicking JD

    更新日期:2005-02-01 00:00:00

  • Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins.

    abstract::The obligatory intracellular bacterial pathogens Anaplasma and Ehrlichia infect leukocytes by hijacking host-cell components and processes. The type IV secretion system is up-regulated during infection. Among type IV secretion candidate substrates, an ankyrin repeat protein of Anaplasma phagocytophilum, AnkA, is deliv...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2009.12.008

    authors: Rikihisa Y,Lin M

    更新日期:2010-02-01 00:00:00

  • Membrane trafficking and remodeling at the host-parasite interface.

    abstract::Membrane shape is functionally linked with many cellular processes. The limiting membrane of vacuoles containing Toxoplasma gondii and Plasmodium apicomplexan parasites lies at the host-parasite interface. This membrane comprises intra-vacuolar and extra-vacuolar tubulo-vesicular deformations, which influence host-par...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2017.11.013

    authors: Santi-Rocca J,Blanchard N

    更新日期:2017-12-01 00:00:00

  • The direct genetic encoding of pyrrolysine.

    abstract::Pyrrolysine is an amino acid encoded by the amber codon in genes required for methylamine utilization by members of the Methanosarcinaceae. Pyrrolysine and selenocysteine share the distinction of being the only two non-canonical amino acids that have entered natural genetic codes. Recent experiments have shown that en...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2005.10.009

    authors: Krzycki JA

    更新日期:2005-12-01 00:00:00

  • The tritrophic trinity: a source of pollutant-degrading enzymes and its implications for phytoremediation.

    abstract::Barring bioavailability and nutritional limitations, virtually all organic anthropogenic chemicals can be naturally biodegraded. It is to this phenomenon we owe thanks to the long established 'tritrophic trinity' of microbe-plant-insect interactions. Over hundreds of millennia these organisms have coevolved, producing...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2004.04.007

    authors: Singer AC,Thompson IP,Bailey MJ

    更新日期:2004-06-01 00:00:00

  • The cyanobacterial clock and metabolism.

    abstract::Cyanobacteria possess the simplest known circadian clock, which presents a unique opportunity to study how rhythms are generated and how input signals from the environment reset the clock time. The kaiABC locus forms the core of the oscillator, and the remarkable ability to reconstitute oscillations using purified Kai...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2014.02.010

    authors: Pattanayak G,Rust MJ

    更新日期:2014-04-01 00:00:00

  • Signaling diversity and evolution of extracytoplasmic function (ECF) σ factors.

    abstract::Extracytoplasmic function σ factors (ECFs) represent a fundamental and widely distributed principle of bacterial signal transduction that connects the perception of a stimulus (input) with the induction of an appropriate set of genes (output). In recent years, comparative genomics analyses have not only allowed a syst...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2013.02.001

    authors: Mascher T

    更新日期:2013-04-01 00:00:00

  • Growth rate and cell size: a re-examination of the growth law.

    abstract::Research into the mechanisms regulating bacterial cell size has its origins in a single paper published over 50 years ago. In it Schaechter and colleagues made the observation that the chemical composition and size of a bacterial cell is a function of growth rate, independent of the medium used to achieve that growth ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2015.01.011

    authors: Vadia S,Levin PA

    更新日期:2015-04-01 00:00:00

  • Genetic code ambiguity: an unexpected source of proteome innovation and phenotypic diversity.

    abstract::Translation of the genome into the proteome is a highly accurate biological process. However, the molecular mechanisms involved in protein synthesis are not error free and downstream protein quality control systems are needed to counteract the negative effects of translational errors (mistranslation) on proteome and c...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2009.09.004

    authors: Moura GR,Carreto LC,Santos MA

    更新日期:2009-12-01 00:00:00

  • Gene expression in Kinetoplastids.

    abstract::Kinetoplastid parasites adapt to different environments with wide-reaching control of gene expression, but transcription of nuclear protein-coding genes is polycistronic: there is no individual control of transcription initiation. Mature mRNAs are made by co-transcriptional trans splicing and polyadenylation, and comp...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2016.04.018

    authors: Clayton CE

    更新日期:2016-08-01 00:00:00

  • Hfq: the flexible RNA matchmaker.

    abstract::The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-term...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2016.02.003

    authors: Updegrove TB,Zhang A,Storz G

    更新日期:2016-04-01 00:00:00

  • Bacterial solute uptake and efflux systems.

    abstract::The recent discovery of binding protein dependent secondary transporters and the ever-growing family of membrane potential generating secondary transporters emphasize the diversity of transport systems in both the mechanistical and physiological sense. The vast amount of data on the lactose permease is now beginning t...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5274(98)80018-0

    authors: Lolkema JS,Poolman B,Konings WN

    更新日期:1998-04-01 00:00:00

  • Metal-homeostasis in the pathobiology of the opportunistic human fungal pathogen Aspergillus fumigatus.

    abstract::In contrast to obligate pathogens opportunistic pathogens such as Aspergillus fumigatus do not need a specific host to propagate or survive. However several characteristics of the saprophytic life-style and the selective pressure encountered in the primary ecological niche contribute to the virulence of A. fumigatus. ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2017.11.015

    authors: Blatzer M,Latgé JP

    更新日期:2017-12-01 00:00:00

  • Transitions and transmission: behavior and physiology as drivers of honey bee-associated microbial communities.

    abstract::Microbial communities have considerable impacts on animal health. However, only in recent years have the host factors impacting microbiome composition been explored. An increasing wealth of microbiome data in combination with decades of research on behavior, physiology, and development have resulted in the European ho...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2019.08.001

    authors: Miller DL,Parish AJ,Newton IL

    更新日期:2019-08-01 00:00:00

  • Global relative and absolute quantitation in microbial proteomics.

    abstract::Proteomic studies are designed to yield either qualitative information on proteins (identification, distribution, posttranslational modifications, interactions, structure and function) or quantitative information (abundance, distribution within different localizations, temporal changes in abundance due to synthesis an...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2012.02.005

    authors: Otto A,Bernhardt J,Hecker M,Becher D

    更新日期:2012-06-01 00:00:00

  • Molecular and cellular interactions defining the tropism of Plasmodium vivax for reticulocytes.

    abstract::Plasmodium vivax is uniquely restricted to invading reticulocytes, the youngest of red blood cells. Parasite invasion relies on the sequential deployment of multiple parasite invasion ligands. Correct targeting of the host reticulocyte is mediated by two families of invasion ligands: the reticulocyte binding proteins ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2018.10.002

    authors: Kanjee U,Rangel GW,Clark MA,Duraisingh MT

    更新日期:2018-12-01 00:00:00

  • Cell biology of corn smut disease-Ustilago maydis as a model for biotrophic interactions.

    abstract::Ustilago maydis is a well-established model system for biotrophic fungal plant pathogens. The fungus has a dimorphic life cycle with a yeast-like saprophytic phase switching to filamentous, pathogenic growth upon hyphal fusion. Due to its highly differentiated development and the amenability for reverse-genetics U. ma...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2016.07.020

    authors: Matei A,Doehlemann G

    更新日期:2016-12-01 00:00:00

  • Prospects for new antitubercular drugs.

    abstract::The inexorable rise in cases of tuberculosis worldwide, fuelled by the HIV epidemic, highlights the need for new drugs and particularly those that can shorten the duration of treatment. Clinical trials of existing broad-spectrum agents such as the fluoroquinolone moxifloxacin are proceeding, on the basis of efficacy i...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2004.08.011

    authors: Duncan K,Barry CE 3rd

    更新日期:2004-10-01 00:00:00

  • Cytoskeleton and motor proteins in filamentous fungi.

    abstract::In filamentous fungi, the actin cytoskeleton is required for polarity establishment and maintenance at hyphal tips and for formation of a contractile ring at sites of septation. Recently, formins have been identified as Arp (actin-related protein) 2/3-independent nucleators of actin polymerization, and filamentous fun...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2003.10.009

    authors: Xiang X,Plamann M

    更新日期:2003-12-01 00:00:00

  • Taking the pseudo out of pseudogenes.

    abstract::Pseudogenes are defined as fragments of once-functional genes that have been silenced by one or more nonsense, frameshift or missense mutations. Despite continuing increases in the speed of sequencing and annotating bacterial genomes, the identification and categorisation of pseudogenes remains problematic. Even when ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2014.11.012

    authors: Goodhead I,Darby AC

    更新日期:2015-02-01 00:00:00

  • Anti-infective vaccination in the 21st century-new horizons for personal and public health.

    abstract::The 21st century has seen the licensure of new anti-infective vaccines that have demonstrated their benefit for both individual and population (herd) protection. Despite this there are still many human pathogens for which no vaccine is available. As we learn more about these pathogens, and as technologies advance, mor...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2015.07.006

    authors: Scully IL,Swanson K,Green L,Jansen KU,Anderson AS

    更新日期:2015-10-01 00:00:00

  • The mycobiota: fungi take their place between plants and bacteria.

    abstract::Eukaryotes host numerous intracellular and associated microbes in their microbiota. Fungi, the so-called Mycobiota, are important members of both human and plant microbiota. Moreover, members of the plant mycobiota host their own microbiota on their surfaces and inside their hyphae. The microbiota of the mycobiota inc...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2019.08.004

    authors: Bonfante P,Venice F,Lanfranco L

    更新日期:2019-06-01 00:00:00

  • Heterocyst development in Anabaena.

    abstract::Many filamentous nitrogen-fixing cyanobacteria protect nitrogenase from oxygen in differentiated cells called heterocysts. Heterocyst development is controlled by the availability of nitrogen compounds in the environment and by intrinsic factors that regulate the frequency and pattern of heterocysts along vegetative c...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2003.10.004

    authors: Golden JW,Yoon HS

    更新日期:2003-12-01 00:00:00

  • Brucella T4SS: the VIP pass inside host cells.

    abstract::For many Gram-negative bacteria, like Brucella, the type IV secretion system (T4SS) has a critical role in bacterial virulence. In Brucella, the VirB T4SS permits the injection of bacterial effectors inside host cells, leading to subversion of signaling pathways and favoring bacterial growth and pathogenesis. The virB...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2012.11.005

    authors: Lacerda TL,Salcedo SP,Gorvel JP

    更新日期:2013-02-01 00:00:00

  • Bioengineering novel in vitro metabolic pathways using synthetic biology.

    abstract::Huge numbers of enzymes have evolved in nature to function in aqueous environments at moderate temperatures and neutral pH. This gives us, in principle, the unique opportunity to construct multistep reaction systems of considerable catalytic complexity in vitro. However, this opportunity is rarely exploited beyond res...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2007.05.009

    authors: Meyer A,Pellaux R,Panke S

    更新日期:2007-06-01 00:00:00

  • Genetic analyses of bacterial biofilm formation.

    abstract::Bacterial biofilms are generally described as surface-associated bacterial communities comprising exopolysaccharide-surrounded microcolonies. Interspersed between these microcolonies are water-filled channels that may serve as primitive circulatory systems. Over the past few years, much progress has been made in our u...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5274(99)00028-4

    authors: Pratt LA,Kolter R

    更新日期:1999-12-01 00:00:00

  • Quantitative bacterial transcriptomics with RNA-seq.

    abstract::RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.mib.2014.11.011

    authors: Creecy JP,Conway T

    更新日期:2015-02-01 00:00:00

  • From motility to virulence: Sensing and responding to environmental signals in Vibrio cholerae.

    abstract::Sensing its changing environment is key for Vibrio cholerae when making the transition from an aquatic lifestyle to one more suited to a human host. An inverse correlation between motility and virulence gene expression has been reported, with the NADH : ubiquinone oxidoreductase system which powers motility by generat...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5274(03)00032-8

    authors: Krukonis ES,DiRita VJ

    更新日期:2003-04-01 00:00:00