Wax ester production by bacteria.


:The enzymological and genetic aspects of microbial metabolism of hydrocarbons have been extensively revealed. Such molecular information is useful for understanding the bioremediation of oil spill environments and production of hydrocarbon-specific fine chemicals.


Curr Opin Microbiol


Ishige T,Tani A,Sakai Y,Kato N




Has Abstract


2003-06-01 00:00:00














  • Host-microbe interactions: Malassezia and human skin.

    abstract::The skin is our first line of defense, protecting us from invasion and evaporation. Its variable structure, changing geography, and complex immune repertoire provide a vast interface for our cutaneous microbial community. Skin is inhabited by many thousands of microbes, but this review focuses on the dominant eukaryot...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Grice EA,Dawson TL 23⁎Jr

    更新日期:2017-12-01 00:00:00

  • Epigenetic regulation of the bacterial cell cycle.

    abstract::N(6)-methyl-adenines can serve as epigenetic signals for interactions between regulatory DNA sequences and regulatory proteins that control cellular functions, such as the initiation of chromosome replication or the expression of specific genes. Several of these genes encode master regulators of the bacterial cell cyc...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Collier J

    更新日期:2009-12-01 00:00:00

  • How do we compare hundreds of bacterial genomes?

    abstract::The genomic revolution is fully upon us in 2006 and the pace of discovery is set to accelerate with the emergence of ultra-high-throughput sequencing technologies. Our complete genome collection of bacteria and archaea continues to grow in number and diversity, as genome sequencing is applied to an array of new proble...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Field D,Wilson G,van der Gast C

    更新日期:2006-10-01 00:00:00

  • Fasciola hepatica, TGF-β and host mimicry: the enemy within.

    abstract::Helminths parasites undergo developmental changes and migration within their definitive host, in addition to establishing chronic infection. Essential to this is the evasion of host immune responses; the canonical Th2 response is effective at removing parasites resident in the intestine. Conversely, helminths also pro...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Musah-Eroje M,Flynn RJ

    更新日期:2018-12-01 00:00:00

  • Metagenomic exploration of antibiotic resistance in soil.

    abstract::The ongoing development of metagenomic approaches is providing the means to explore antibiotic resistance in nature and address questions that could not be answered previously with conventional culture-based strategies. The number of available environmental metagenomic sequence datasets is rapidly expanding and hencef...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Monier JM,Demanèche S,Delmont TO,Mathieu A,Vogel TM,Simonet P

    更新日期:2011-06-01 00:00:00

  • Cyclic (di)nucleotides: the common language shared by microbe and host.

    abstract::Fluency in a common language allows individuals to convey information and carry out complex activities that otherwise would be difficult or even impossible without the benefit of shared communication. Cyclic (di)nucleotides have recently been recognized as such an accessible language understood by both microbe and the...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Gao J,Tao J,Liang W,Jiang Z

    更新日期:2016-04-01 00:00:00

  • Unveiling cellular biochemical reactions via metabolomics-driven approaches.

    abstract::Despite the widespread availability of genome sequences and the systematic assignment of individual open reading frames, many of the activities of metabolic enzymes are still veiled. It is difficult to assign biochemical functions to enzymes and uncover the in vivo regulation of their enzymatic activities, but this is...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Saito N,Ohashi Y,Soga T,Tomita M

    更新日期:2010-06-01 00:00:00

  • Plasticity in mast cell responses during bacterial infections.

    abstract::Mast cells (MCs) have been implicated in orchestrating the host's early innate immune and adaptive immune responses in several models of acute bacterial infections. Most of this activity results in early clearance of the bacteria and timely resolution of infection. However, during chronic infections because of the pro...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Chan CY,St John AL,Abraham SN

    更新日期:2012-02-01 00:00:00

  • Legionella quorum sensing and its role in pathogen-host interactions.

    abstract::Legionella pneumophila is a water-borne opportunistic pathogen causing a life-threatening pneumonia called 'Legionnaires' disease'. The Legionella quorum sensing (Lqs) system produces and responds to the α-hydroxyketone signaling molecule 3-hydroxypentadecane-4-one (Legionella autoinducer-1, LAI-1). The Lqs system con...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Personnic N,Striednig B,Hilbi H

    更新日期:2018-02-01 00:00:00

  • Modulation of natural killer cell activity by viruses.

    abstract::Since their discovery, our understanding of NK cells has evolved from branding them marginal innate immunity cells to key players in anti-viral and anti-tumor immunity. Importance of NK cells in control of various viral infections is perhaps best illustrated by the existence of plethora of viral mechanisms aimed to mo...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Lisnić VJ,Krmpotić A,Jonjić S

    更新日期:2010-08-01 00:00:00

  • Inhibition of host cell signal transduction by Leishmania: observations relevant to the selective impairment of IL-12 responses.

    abstract::Leishmania parasites are able to delay the onset of cell-mediated immunity by selectively impairing the ability of infected macrophages to produce interleukin (IL)-12. Leishmania infection arrests the JAK/STAT-mediated signal transduction involved in activation of the IL-12 p40 promoter; the phosphorylation defects ma...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: McDowell MA,Sacks DL

    更新日期:1999-08-01 00:00:00

  • The tritrophic trinity: a source of pollutant-degrading enzymes and its implications for phytoremediation.

    abstract::Barring bioavailability and nutritional limitations, virtually all organic anthropogenic chemicals can be naturally biodegraded. It is to this phenomenon we owe thanks to the long established 'tritrophic trinity' of microbe-plant-insect interactions. Over hundreds of millennia these organisms have coevolved, producing...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Singer AC,Thompson IP,Bailey MJ

    更新日期:2004-06-01 00:00:00

  • Eco-Aging: stem cells and microbes are controlled by aging antagonist FoxO.

    abstract::The review highlights the dual role that the conserved master regulator FoxO has in aging by coordinating both stem cell proliferation and antimicrobial peptides, effector molecules of the innate immune system. As observed in non-senescent Hydra, continuously high activity of the transcription factor FoxO contributes ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Mortzfeld BM,Bosch TC

    更新日期:2017-08-01 00:00:00

  • Microbial metaproteomics: identifying the repertoire of proteins that microorganisms use to compete and cooperate in complex environmental communities.

    abstract::The availability of genome information for microbial consortia, including unculturable species, from environmental samples has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. This provides a unique opportunity to characterize the molecular activi...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Hettich RL,Sharma R,Chourey K,Giannone RJ

    更新日期:2012-06-01 00:00:00

  • A perfect genome annotation is within reach with the proteomics and genomics alliance.

    abstract::High-throughput identification of proteins and their accurate partial sequencing by shotgun nanoLC-MS/MS are now feasible for any cellular model at a full genomic scale. Proteogenomics is the integration of these data with the genome. Mining microbial proteomes allows validation of predicted orphan genes and correctio...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Armengaud J

    更新日期:2009-06-01 00:00:00

  • Type III secretion systems shape up as they ship out.

    abstract::Virulence associated protein type III secretion systems (T3SSs) are intricately structured organic nanosyringes that achieve the translocation of bacterial proteins from the prokaryotic cytoplasm across three membranes into the host cytosol. The substrates for these systems number in the hundreds, with remarkably dive...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Marlovits TC,Stebbins CE

    更新日期:2010-02-01 00:00:00

  • The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine.

    abstract::Candida albicans is a regular member of the intestinal microbiota in the majority of the human population. This underscores C. albicans' adaptation to life in the intestine without inducing competitive interactions with other microbes, or immune responses detrimental to its survival. However, specific conditions such ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Kumamoto CA,Gresnigt MS,Hube B

    更新日期:2020-08-01 00:00:00

  • Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

    abstract::Trypanosomes and Leishmania contain an abundance of stage-regulated cysteine proteinases encoded by several gene families. Analysis of parasites rendered defective in cysteine proteinase function, either through genetic manipulation or through the use of specific inhibitors, has revealed roles for the enzymes in paras...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Mottram JC,Brooks DR,Coombs GH

    更新日期:1998-08-01 00:00:00

  • Imaging bacteria inside their host by cryo-focused ion beam milling and electron cryotomography.

    abstract::Bacterium-host interactions are important for diverse ecological settings including pathogenicity and symbiosis. Electron cryotomography is a powerful method for studying the macromolecular complexes that mediate such interactions in situ. The main limitation of electron cryotomography is its restriction to relatively...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Medeiros JM,Böck D,Pilhofer M

    更新日期:2018-06-01 00:00:00

  • Functional requirements of cellular differentiation: lessons from Bacillus subtilis.

    abstract::Successful execution of differentiation programs requires cells to assess multitudes of internal and external cues and respond with appropriate gene expression programs. Here, we review how Bacillus subtilis sporulation network deals with these tasks focusing on the lessons generalizable to other systems. With feedfor...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Narula J,Fujita M,Igoshin OA

    更新日期:2016-12-01 00:00:00

  • Antibacterials - mechanisms of action.

    abstract::Recent studies on antibacterials have focused on the development of antimycobacterial agents and antibacterial peptides, and on furthering the understanding of agents that have been available for several decades, including imidazoles, beta-lactams and quinolones. New areas of research include antisense oligonucleotide...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Piddock LJ

    更新日期:1998-10-01 00:00:00

  • The role of giant viruses of amoebas in humans.

    abstract::Since 2003, dozens of giant viruses that infect amoebas (GVA), including mimiviruses and marseilleviruses, have been discovered. These giants appear to be common in our biosphere. From the onset, their presence and possible pathogenic role in humans have been serendipitously observed or investigated using a broad rang...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Colson P,Aherfi S,La Scola B,Raoult D

    更新日期:2016-06-01 00:00:00

  • Heterocyst development in Anabaena.

    abstract::Many filamentous nitrogen-fixing cyanobacteria protect nitrogenase from oxygen in differentiated cells called heterocysts. Heterocyst development is controlled by the availability of nitrogen compounds in the environment and by intrinsic factors that regulate the frequency and pattern of heterocysts along vegetative c...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Golden JW,Yoon HS

    更新日期:2003-12-01 00:00:00

  • Mycobacterium tuberculosis in the post-genomic age.

    abstract::Since the publication of the complete genome sequence of Mycobacterium tuberculosis in 1998, there has been a marked intensification and diversification of activities in the field of tuberculosis research. Among the areas that have advanced spectacularly are comparative genomics, functional genomics-notably the study ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Domenech P,Barry CE 3rd,Cole ST

    更新日期:2001-02-01 00:00:00

  • Viral hijacking of the host ubiquitin system to evade interferon responses.

    abstract::The post-translational attachment of ubiquitin or ubiquitin-like modifiers (ULMs) to proteins regulates many cellular processes including the generation of innate and adaptive immune responses to pathogens. Vice versa, pathogens counteract immune defense by inhibiting or redirecting the ubiquitination machinery of the...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Viswanathan K,Früh K,DeFilippis V

    更新日期:2010-08-01 00:00:00

  • P. aeruginosa quorum-sensing systems and virulence.

    abstract::Quorum sensing is an important mechanism for the regulation of genes in many Gram-negative and Gram-positive bacteria. In the opportunistic pathogen Pseudomonas aeruginosa, the absence of one or more components of the quorum-sensing system results in a significant reduction in virulence. Recent advances in the past ye...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Smith RS,Iglewski BH

    更新日期:2003-02-01 00:00:00

  • Small RNAs establish gene expression thresholds.

    abstract::The central role of small RNAs in regulating bacterial gene expression has been elucidated in the past years. Typically, small RNAs act via specific basepairing with target mRNAs, leading to modulation of translation initiation and mRNA stability. Quantitative studies suggest that small RNA regulation is characterized...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Levine E,Hwa T

    更新日期:2008-12-01 00:00:00

  • Robust peptidoglycan growth by dynamic and variable multi-protein complexes.

    abstract::In Gram-negative bacteria such as Escherichia coli the peptidoglycan sacculus resides in the periplasm, a compartment that experiences changes in pH value, osmolality, ion strength and other parameters depending on the cell's environment. Hence, the cell needs robust peptidoglycan growth mechanisms to grow and divide ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Pazos M,Peters K,Vollmer W

    更新日期:2017-04-01 00:00:00

  • Leveraging non-human primates for exploring the social transmission of microbes.

    abstract::Host social interactions can provide multiple complex pathways for microbial transmission. Here, we suggest non-human primates as models to study the social transmission of commensal or mutualistic microbes due to their high sociality, wide range of group compositions and dominance structures, and diverse group intera...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Kuthyar S,Manus MB,Amato KR

    更新日期:2019-08-01 00:00:00

  • Anopheles gambiae pathogen susceptibility: the intersection of genetics, immunity and ecology.

    abstract::Mosquitoes are the major arthropod vectors of human diseases such as malaria and viral encephalitis. However, each mosquito species does not transmit every pathogen, owing to reasons that include specific evolutionary histories, mosquito immune system structure, and ecology. Even a competent vector species for a patho...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Mitri C,Vernick KD

    更新日期:2012-06-01 00:00:00