How and why myxobacteria talk to each other.

abstract：:Endosymbiotic theory goes back over 100 years. It explains the similarity of chloroplasts and mitochondria to free-living prokaryotes by suggesting that the organelles arose from prokaryotes through (endo)symbiosis. Gene trees provide important evidence in favour of symbiotic theory at a coarse-grained level, but the ...

journal_title：Current opinion in microbiology

authors： Zimorski V,Ku C,Martin WF,Gould SB

更新日期：2014-12-01 00:00:00

abstract：:Macrophages protect their host by engulfing foreign bodies within phagosomes that rapidly develop into microbicidal organelles. Numerous pathogens, such as species of Toxoplasma, Leishmania, Mycobacterium, Salmonella and Legionella, thrive in human macrophages, sometimes with disastrous effects. Defining the survival ...

journal_title：Current opinion in microbiology

authors： Amer AO,Swanson MS

更新日期：2002-02-01 00:00:00

abstract：:Huge numbers of enzymes have evolved in nature to function in aqueous environments at moderate temperatures and neutral pH. This gives us, in principle, the unique opportunity to construct multistep reaction systems of considerable catalytic complexity in vitro. However, this opportunity is rarely exploited beyond res...

journal_title：Current opinion in microbiology

authors： Meyer A,Pellaux R,Panke S

更新日期：2007-06-01 00:00:00

abstract：:The human pathogenic Yersinia species cause diseases that represent a significant source of morbidity and mortality. Despite this, specific mechanisms underlying Yersinia pathogenesis and protective host responses remain poorly understood. Recent studies have shown that Yersinia disrupt cell death pathways, perturb in...

journal_title：Current opinion in microbiology

authors： Chung LK,Bliska JB

更新日期：2016-02-01 00:00:00

abstract：:Upon infection, both DNA and RNA viruses can be sensed by pattern recognition receptors (PRRs) in the cytoplasm or the nucleus to activate antiviral innate immunity. Sensing of viral products leads to the activation of a signaling cascade that ultimately results in transcriptional activation of type I and III interfer...

journal_title：Current opinion in microbiology

authors： Beachboard DC,Horner SM

更新日期：2016-08-01 00:00:00

abstract：:The historical paradigm of the deep ocean as a biological 'desert' has shifted to one of a 'rainforest' owing to the isolation of many novel microbes and their associated bioactive compounds. Recently, there has been an explosion of information about novel bioactive compounds that have been isolated from marine microb...

journal_title：Current opinion in microbiology

authors： Zhang L,An R,Wang J,Sun N,Zhang S,Hu J,Kuai J

更新日期：2005-06-01 00:00:00

abstract：:Dectin-1 is an innate immune pattern recognition receptor (PRR) that, through its ability to bind β-glucans, is involved in the recognition of several pathogenic fungi. Dectin-1 can stimulate a variety of cellular responses via the Syk/CARD9 signalling pathway, including phagocytosis, cytokine production and the respi...

journal_title：Current opinion in microbiology

authors： Drummond RA,Brown GD

更新日期：2011-08-01 00:00:00

abstract：:The glideosome is a unique attribute of the Apicomplexa phylum. This myosin-based machine powers parasite motility, migration across biological barriers, host cell invasion and egress from infected cells. The timing, duration and orientation of gliding motility are tightly regulated to assure establishment of infectio...

journal_title：Current opinion in microbiology

authors： Daher W,Soldati-Favre D

更新日期：2009-08-01 00:00:00

abstract：:The family Arenaviridae consists of a unique genus (Arenavirus) that currently comprises 22 viral species, as recognized by the International Committee for Taxonomy of Viruses. Seven newly discovered represent putative new species. Here, our aims were to provide the most comprehensive phylogenetic analysis of members ...

journal_title：Current opinion in microbiology

authors： Charrel RN,de Lamballerie X,Emonet S

更新日期：2008-08-01 00:00:00

abstract：:During the past ten years, species-rich nations in the developing world have sought to capitalize on their 'biological patrimony' through a variety of business relationships with multinational corporations as a means of underwriting their conservation efforts. Initially lauded, these relationships have generated more ...

journal_title：Current opinion in microbiology

authors： Garrity GM,Hunter-Cevera J

更新日期：1999-06-01 00:00:00

abstract：:The RNA chaperone protein Hfq is critical to the function of small, base pairing RNAs in many bacteria. In the past few years, structures and modeling of wild type Hfq and assays of various mutants have documented that the homohexameric Hfq ring can contact RNA at four sites (proximal face, distal face, rim and C-term...

journal_title：Current opinion in microbiology

authors： Updegrove TB,Zhang A,Storz G

更新日期：2016-04-01 00:00:00

abstract：:Sexual development in filamentous ascomycetes requires mating-type genes to mediate recognition of compatible cell and nuclear types. Characterization of mating-type genes from various fungi shows that they primarily encode transcriptional regulators. Recent studies on mating-type-specific pheromones and internuclear ...

journal_title：Current opinion in microbiology

authors： Shiu PK,Glass NL

更新日期：2000-04-01 00:00:00

abstract：:Host social interactions can provide multiple complex pathways for microbial transmission. Here, we suggest non-human primates as models to study the social transmission of commensal or mutualistic microbes due to their high sociality, wide range of group compositions and dominance structures, and diverse group intera...

journal_title：Current opinion in microbiology

authors： Kuthyar S,Manus MB,Amato KR

更新日期：2019-08-01 00:00:00

abstract：:Stan Falkow looked at the world with his eyes peering from the outer membrane of a gram-negative bacterium. It was a great vantage point from which to dream about the possible superpowers these organisms might have. He mused about these dreams with his trainees who sometimes found through rigorous scientific explorati...

journal_title：Current opinion in microbiology

authors： Starnbach MN

更新日期：2020-04-01 00:00:00

abstract：:Kinetoplastid parasites adapt to different environments with wide-reaching control of gene expression, but transcription of nuclear protein-coding genes is polycistronic: there is no individual control of transcription initiation. Mature mRNAs are made by co-transcriptional trans splicing and polyadenylation, and comp...

journal_title：Current opinion in microbiology

authors： Clayton CE

更新日期：2016-08-01 00:00:00

abstract：:The discovery of tubulin-like cytoskeletal proteins carried on the genomes of bacteriophages that are actively used for phage propagation during both the lytic and lysogenic cycle have revealed that there at least two ways that viruses can utilize a cytoskeleton; co-opt the host cytoskeleton or bring their own homolog...

journal_title：Current opinion in microbiology

authors： Erb ML,Pogliano J

更新日期：2013-12-01 00:00:00

abstract：:Trypanosomes and Leishmania contain an abundance of stage-regulated cysteine proteinases encoded by several gene families. Analysis of parasites rendered defective in cysteine proteinase function, either through genetic manipulation or through the use of specific inhibitors, has revealed roles for the enzymes in paras...

journal_title：Current opinion in microbiology

authors： Mottram JC,Brooks DR,Coombs GH

更新日期：1998-08-01 00:00:00

abstract：:The genomic revolution is fully upon us in 2006 and the pace of discovery is set to accelerate with the emergence of ultra-high-throughput sequencing technologies. Our complete genome collection of bacteria and archaea continues to grow in number and diversity, as genome sequencing is applied to an array of new proble...

journal_title：Current opinion in microbiology

authors： Field D,Wilson G,van der Gast C

更新日期：2006-10-01 00:00:00

abstract：:Many filamentous nitrogen-fixing cyanobacteria protect nitrogenase from oxygen in differentiated cells called heterocysts. Heterocyst development is controlled by the availability of nitrogen compounds in the environment and by intrinsic factors that regulate the frequency and pattern of heterocysts along vegetative c...

journal_title：Current opinion in microbiology

authors： Golden JW,Yoon HS

更新日期：2003-12-01 00:00:00

abstract：:Germ line encoded antiviral defenses in vertebrate cells tend to be either broadly acting factors that exploit general features of viral replication or effectors with strong pathogen preference by virtue of specific recognition of viral proteins. The Mx GTPases, however, are atypical since they have broad antiviral ac...

journal_title：Current opinion in microbiology

authors： Mitchell PS,Emerman M,Malik HS

更新日期：2013-08-01 00:00:00

abstract：:Bacterial biofilms are generally described as surface-associated bacterial communities comprising exopolysaccharide-surrounded microcolonies. Interspersed between these microcolonies are water-filled channels that may serve as primitive circulatory systems. Over the past few years, much progress has been made in our u...

journal_title：Current opinion in microbiology

authors： Pratt LA,Kolter R

更新日期：1999-12-01 00:00:00

abstract：:Schizosaccharomyces pombe is a useful model system for understanding many aspects of eukaryotic cell growth. Studies of S. pombe have identified novel genes that function in the regulation of iron homeostasis. In response to high levels of iron, Fep1 represses the expression of several genes involved in the acquisitio...

journal_title：Current opinion in microbiology

authors： Labbé S,Khan MG,Jacques JF

更新日期：2013-12-01 00:00:00

abstract：:The availability of a large number of sequenced microbial genomes allows us to conduct systematic studies on microbial gene regulatory systems. Computational methods, using comparative genomics approaches, are powerful tools to understand their mechanisms and evolutionary history. Recent advances in computational meth...

journal_title：Current opinion in microbiology

authors： Stormo GD,Tan K

更新日期：2002-04-01 00:00:00

abstract：:Organisms do not exist isolated from each other, but constantly interact. Cells can sense the presence of interaction partners by a range of receptors and, via complex regulatory networks, specifically react by changing the expression of many of their genes. Technological advances in next-generation sequencing over th...

journal_title：Current opinion in microbiology

authors： Wolf T,Kämmer P,Brunke S,Linde J

更新日期：2018-04-01 00:00:00

abstract：:In part, members of the genus Streptomyces have been studied because they produce many important secondary metabolites with antibiotic activity and for the interest in their relatively elaborate life cycle. These sporulating filamentous bacteria are remarkably synchronous for division and genome segregation in special...

journal_title：Current opinion in microbiology

authors： McCormick JR

更新日期：2009-12-01 00:00:00

abstract：:Recent studies based on metagenomics and other molecular techniques have permitted a detailed knowledge of the microbial diversity and metabolic activities of microorganisms in hypersaline environments. The current accepted model of community structure in hypersaline environments is that the square archaeon Haloquadra...

journal_title：Current opinion in microbiology

authors： Ventosa A,de la Haba RR,Sánchez-Porro C,Papke RT

更新日期：2015-06-01 00:00:00

abstract：:Bacteria utilize a diverse set of nucleotide second messengers to regulate cellular responses by binding macromolecular receptors (RNAs and proteins). Recent studies on cyclic di-GMP (c-di-GMP) have shown that this signaling molecule binds multiple receptors to regulate different steps in the same biological process. ...

journal_title：Current opinion in microbiology

authors： Orr MW,Galperin MY,Lee VT

更新日期：2016-12-01 00:00:00

abstract：:N(6)-methyl-adenines can serve as epigenetic signals for interactions between regulatory DNA sequences and regulatory proteins that control cellular functions, such as the initiation of chromosome replication or the expression of specific genes. Several of these genes encode master regulators of the bacterial cell cyc...

journal_title：Current opinion in microbiology

authors： Collier J

更新日期：2009-12-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is a clinically significant herpes virus that maintains a lifelong infection in the host. HCMV infection of endothelial cells and macrophages plays an important role in the establishment of latency and persistence, which appears critical for the maintenance of HCMV within the host. HCMV in...

journal_title：Current opinion in microbiology

authors： Jarvis MA,Nelson JA

更新日期：2002-08-01 00:00:00

abstract：:An increasingly diverse array of clinically relevant animal models of candidiasis have been established that mimic both the immune perturbations of the host and tissue-specific features of candidiasis in humans. Cause-and-effect analysis of Candida host-pathogen interactions using these animal models has made a quantu...

journal_title：Current opinion in microbiology

authors： de Repentigny L

更新日期：2004-08-01 00:00:00