Abstract:
:The discovery of tubulin-like cytoskeletal proteins carried on the genomes of bacteriophages that are actively used for phage propagation during both the lytic and lysogenic cycle have revealed that there at least two ways that viruses can utilize a cytoskeleton; co-opt the host cytoskeleton or bring their own homologues. Either strategy underscores the deep evolutionary relationship between viruses and cytoskeletal proteins and points to a conservation of viral strategies that crosses the kingdoms of life. Here we review some of the most recent discoveries about tubulin cytoskeletal elements encoded by phages and compare them to some of the strategies utilized by the gammaherpesvirues of mammalian cells.
journal_name
Curr Opin Microbioljournal_title
Current opinion in microbiologyauthors
Erb ML,Pogliano Jdoi
10.1016/j.mib.2013.08.007subject
Has Abstractpub_date
2013-12-01 00:00:00pages
786-9issue
6eissn
1369-5274issn
1879-0364pii
S1369-5274(13)00149-5journal_volume
16pub_type
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