Abstract：
:Since the past decades, oligosaccharides are considered for their potential biological activities. To exploit them, it was essential to obtain pure molecules in large amounts. Several strategies were developed to produce specific sugar sequences with specific substitution patterns from land plants and algae polysaccharides. Then, pure oligosaccharides were analyzed for their potential biological activities and relations between oligomers structure and function were tackled. First they can be health beneficial molecules when they are added to the diet to enhance the growth of probiotic bacteria, in that case, oligomers that resist to the digestive process are used as specific substrate for the growth of health beneficial bacteria. In other cases, oligomers have to interact with receptors on cells. In this instance, a specific conformation is needed to allow the sugar sequence to establish specific linkages with the receptor. So, to be adapted to the receptor, the oligosaccharides have to present specific groups to the receptor, there, the polymerization degree of oligosaccharides as well as the flexibility of the glycosidic linkages has to be considered.
journal_name
Curr Opin Microbioljournal_title
Current opinion in microbiologyauthors
Courtois Jdoi
10.1016/j.mib.2009.04.007subject
Has Abstractpub_date
2009-06-01 00:00:00pages
261-73issue
3eissn
1369-5274issn
1879-0364pii
S1369-5274(09)00048-4journal_volume
12pub_type
杂志文章,评审abstract：:One defining feature of apicomplexan parasites is their special ability to actively invade host cells. Although rapid, invasion is a complicated process that requires coordinated activities of host cell attachment, protein secretion, and motility by the parasite. Central to this process is the establishment of a struc...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2011.06.002
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abstract：:For many Gram-negative bacteria, like Brucella, the type IV secretion system (T4SS) has a critical role in bacterial virulence. In Brucella, the VirB T4SS permits the injection of bacterial effectors inside host cells, leading to subversion of signaling pathways and favoring bacterial growth and pathogenesis. The virB...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2012.11.005
更新日期：2013-02-01 00:00:00
abstract：:Cryptosporidium is a leading cause of diarrhea and death in young children and untreated AIDS patients in resource-poor settings, and of waterborne outbreaks of disease in developed countries. However, there is no consistently effective treatment for vulnerable populations. Progress towards development of therapeutics...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2020.10.002
更新日期：2020-12-01 00:00:00
abstract：:The glideosome is a unique attribute of the Apicomplexa phylum. This myosin-based machine powers parasite motility, migration across biological barriers, host cell invasion and egress from infected cells. The timing, duration and orientation of gliding motility are tightly regulated to assure establishment of infectio...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2009.06.008
更新日期：2009-08-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2011.12.014
更新日期：2012-04-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2018.01.001
更新日期：2018-06-01 00:00:00
abstract：:Gram-positive pathogens are a major cause of community-acquired and hospital-acquired infections, and exhibit a remarkable ability to develop antibiotic resistance. Methicillin-resistant Staphylococcus aureus (MRSA), glycopeptide-resistant enterococci (GRE) and multidrug-resistant pneumococci are currently the major r...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2010.08.006
更新日期：2010-10-01 00:00:00
abstract：:Virulence gene regulators RovA, SlyA and PecS comprise a subset of the MarR/SlyA family of transcriptional regulators, which has been shown to be involved in the regulation of virulence genes. These regulators have all been shown to both positively and negatively regulate the expression of multiple genes, involving se...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2006.02.003
更新日期：2006-04-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5274(03)00053-5
更新日期：2003-06-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2015.09.006
更新日期：2015-12-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2016.05.015
更新日期：2016-08-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/s1369-5274(99)00028-4
更新日期：1999-12-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2011.12.001
更新日期：2012-04-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2016-08-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：1998-08-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2016.04.018
更新日期：2016-08-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2016-12-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2009-06-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2003-02-01 00:00:00
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journal_title：Current opinion in microbiology
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更新日期：2019-10-01 00:00:00
abstract：:Arginine is an integral part of host defense when invading pathogens are encountered. The arginine metabolite nitric oxide (NO) confers antimicrobial properties, whereas the metabolite ornithine is utilized for polyamine synthesis. Polyamines are crucial to tissue repair and anti-inflammatory responses. iNOS/arginase ...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2016-02-01 00:00:00
abstract：:Metagenomics is a novel field which deals with the sequencing and study of microbial organisms or viruses isolated directly from a particular environment. This has already provided a wealth of information and new insights for the inhabitants of various environmental niches. For a given sample, one would like to determ...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.mib.2007.08.004
更新日期：2007-10-01 00:00:00
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journal_title：Current opinion in microbiology
pub_type： 杂志文章
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更新日期：1999-10-01 00:00:00
abstract：:Stan Falkow looked at the world with his eyes peering from the outer membrane of a gram-negative bacterium. It was a great vantage point from which to dream about the possible superpowers these organisms might have. He mused about these dreams with his trainees who sometimes found through rigorous scientific explorati...
journal_title：Current opinion in microbiology
pub_type： 杂志文章,评审
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更新日期：2020-04-01 00:00:00
abstract：:Legionella pneumophila is a water-borne opportunistic pathogen causing a life-threatening pneumonia called 'Legionnaires' disease'. The Legionella quorum sensing (Lqs) system produces and responds to the α-hydroxyketone signaling molecule 3-hydroxypentadecane-4-one (Legionella autoinducer-1, LAI-1). The Lqs system con...
journal_title：Current opinion in microbiology
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更新日期：2018-02-01 00:00:00
