Abstract：
:One defining feature of apicomplexan parasites is their special ability to actively invade host cells. Although rapid, invasion is a complicated process that requires coordinated activities of host cell attachment, protein secretion, and motility by the parasite. Central to this process is the establishment of a structure called moving junction (MJ), which forms a tight connection between invading parasite and host cell membranes through which the parasite passes to enter into the host. Although recognized microscopically for decades, molecular characterization of the MJ was only enabled by the recent discovery of components that make up this multi-protein complex. Exciting progress made during the past few years on both the structure and function of the components of the MJ is reviewed here.
journal_name
Curr Opin Microbioljournal_title
Current opinion in microbiologyauthors
Shen B,Sibley LDdoi
10.1016/j.mib.2012.02.007subject
Has Abstractpub_date
2012-08-01 00:00:00pages
449-55issue
4eissn
1369-5274issn
1879-0364pii
S1369-5274(12)00023-9journal_volume
15pub_type
杂志文章,评审abstract：:Sensing its changing environment is key for Vibrio cholerae when making the transition from an aquatic lifestyle to one more suited to a human host. An inverse correlation between motility and virulence gene expression has been reported, with the NADH : ubiquinone oxidoreductase system which powers motility by generat...
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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更新日期：2002-10-01 00:00:00
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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journal_title：Current opinion in microbiology
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更新日期：2005-08-01 00:00:00
