Abstract:
:Bacillus subtilis regulates its ability to differentiate into distinct, co-existing cell types in response to extracellular signaling molecules produced either by itself, or present in its environment. The production of molecules by B. subtilis cells, as well as their response to these signals, is not uniform across the population. There is specificity and heterogeneity both within genetically identical populations as well as at the strain-level and species-level. This review will discuss how extracellular signaling compounds influence B. subtilis multicellularity with regard to matrix-producing cannibal differentiation, germination, and swarming behavior, as well as the specificity of the quorum-sensing peptides ComX and CSF. It will also highlight how imaging mass spectrometry can aid in identifying signaling compounds and contribute to our understanding of the functional relationship between such compounds and multicellular behavior.
journal_name
Curr Opin Microbioljournal_title
Current opinion in microbiologyauthors
Shank EA,Kolter Rdoi
10.1016/j.mib.2011.09.016subject
Has Abstractpub_date
2011-12-01 00:00:00pages
741-7issue
6eissn
1369-5274issn
1879-0364pii
S1369-5274(11)00166-4journal_volume
14pub_type
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
pub_type: 杂志文章,评审
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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journal_title:Current opinion in microbiology
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更新日期:2007-12-01 00:00:00
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journal_title:Current opinion in microbiology
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更新日期:2002-12-01 00:00:00
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journal_title:Current opinion in microbiology
pub_type: 杂志文章,评审
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更新日期:1998-04-01 00:00:00
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journal_title:Current opinion in microbiology
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