The epidemiology of melioidosis in the Balimo region of Papua New Guinea.

Abstract:

:The distribution of Burkholderia pseudomallei was determined in soil collected from a rural district in Papua New Guinea (PNG) where melioidosis had recently been described, predominately affecting children. In 274 samples, 2.6% tested culture-positive for B. pseudomallei. Pulsed-field gel electrophoresis using SpeI digests and rapid polymorphic DNA PCR with five primers demonstrated a single clone amongst clinical isolates and isolates cultured from the environment that was commonly used by children from whom the clinical isolates were derived. We concluded that individuals in this region most probably acquired the organism through close contact with the environment at these sites. Burkholderia thailandensis, a closely related Burkholderia sp. was isolated from 5.5% of samples tested, an observation similar to that of melioidosis-endemic areas in Thailand. This is the first report of an environmental reservoir for melioidosis in PNG and confirms the Balimo district in PNG as melioidosis endemic.

journal_name

Epidemiol Infect

authors

Warner JM,Pelowa DB,Gal D,Rai G,Mayo M,Currie BJ,Govan B,Skerratt LF,Hirst RG

doi

10.1017/S0950268807009429

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

965-71

issue

7

eissn

0950-2688

issn

1469-4409

pii

S0950268807009429

journal_volume

136

pub_type

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