Abstract:
:Conditions and evidence continue to evolve related to the prediction of the prevalence of immunodeficiency-associated long-term vaccine-derived poliovirus (iVDPV) excreters, which affect assumptions related to forecasting risks and evaluating potential risk management options. Multiple recent reviews provided information about individual iVDPV excreters, but inconsistencies among the reviews raise some challenges. This analysis revisits the available evidence related to iVDPV excreters and provides updated model estimates that can support future risk management decisions. The results suggest that the prevalence of iVDPV excreters remains highly uncertain and variable, but generally confirms the importance of managing the risks associated with iVDPV excreters throughout the polio endgame in the context of successful cessation of all oral poliovirus vaccine use.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Kalkowska DA,Pallansch MA,Thompson KMdoi
10.1017/S095026881900181Xsubject
Has Abstractpub_date
2019-10-24 00:00:00pages
e295eissn
0950-2688issn
1469-4409pii
S095026881900181Xjournal_volume
147pub_type
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