Relationship between Legionella spp. and antibody titres at a therapeutic thermal spa in Portugal.

Abstract:

:The presence of Legionella spp. in the water of a Portuguese spa was ascertained during the spa season, between May and November. Simultaneously the prevalence of anti-legionella antibodies in people attending the spa was also investigated. The antibody titres of 172 randomly selected patients and 42 therapists were determined, and compared with a control group of 503 blood donors. Legionellae were present in the spa water at low concentrations, generally lower than 10(3) c.f.u./l. A total of 92 strains representing eight different species or serogroups were isolated; the predominant isolates belonged to Legionella pneumophila serogroup 6 and to L. londiniensis. During the study, no clinical cases of Legionnaires' disease were observed, and the antibody titres were generally low in the groups studied. However, the antibody titres of the patients increased slightly during their stay at the spa, approaching the values for the therapists. Mean antibody titres in the groups related with the spa were significantly higher than those in the blood donors against five of the seven legionella antigens tested. The largest number of elevated antibody titres in the exposed groups were to the L. pneumophila sg 5 and sg 6 antigens.

journal_name

Epidemiol Infect

authors

Rocha G,Veríssimo A,Bowker R,Bornstein N,Da Costa MS

doi

10.1017/s0950268800058143

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

79-88

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

115

pub_type

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