Mycobacterium tuberculosis exposure of livestock in a German dairy farm: implications for intra vitam diagnosis of bovine tuberculosis in an officially tuberculosis-free country.

Abstract:

:Germany has been an officially bovine tuberculosis (bTB)-free (OTF) country since 1996. Gradually rising numbers of bTB herd incidents due to Mycobacterium bovis and M. caprae in North-Western and Southern Germany during the last few years prompted the competent authorities to conduct a nationwide bTB survey in 2013/2014. This led to the detection of a dairy herd in which as many as 55 cattle reacted positively to consecutive intra vitam testing. Test-positive animals lacked visible lesions indicative of bTB at necropsy. Extensive mycobacterial culturing as well as molecular testing of samples from 11 tissues for members of the M. tuberculosis complex (MTC) yielded negative results throughout. However, caseous lymphadenitis of Ln. mandibularis accessorius was observed during meat inspection of a fattening pig from the same farm at regular slaughter at that time. Respective tissue samples tested MTC positive by polymerase chain reaction, and M. tuberculosis T1 family were identified by spoligotyping. Four human reactors within the farmer's family were also found to be immunoreactive. As exposure of livestock to M. tuberculosis is not generally considered, its impact may result in regulatory and practical difficulties when using protocols designed to detect classical bTB, particularly in OTF countries.

journal_name

Epidemiol Infect

authors

Eisenberg T,Nesseler A,Sauerwald C,Kling U,Riße K,Kaim U,Althoff G,Fiege N,Schlez K,Hamann HP,Fawzy A,Moser I,Riße R,Kraft G,Zschöck M,Menge C

doi

10.1017/S0950268815001995

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

724-31

issue

4

eissn

0950-2688

issn

1469-4409

pii

S0950268815001995

journal_volume

144

pub_type

杂志文章
  • Reported foodborne outbreaks due to noroviruses in Belgium: the link between food and patient investigations in an international context.

    abstract::The Belgian data for foodborne norovirus (NoV) outbreaks became available for the first time with the introduction of an extraction and detection protocol for NoV in the National Reference Laboratory for foodborne outbreaks in September 2006. In 2007, 10 NoV foodborne outbreaks were reported affecting 392 persons in B...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268808001830

    authors: Baert L,Uyttendaele M,Stals A,VAN Coillie E,Dierick K,Debevere J,Botteldoorn N

    更新日期:2009-03-01 00:00:00

  • Streptococcal pharyngitis in general practice. 2. A note on dual infection and transient urinary abnormalities.

    abstract::In an incomplete study in 1965 microscopic haematuria in the second or third week after acute pharyngitis was found four times more often in patients with either microbiological or clinical evidence of dual infection with both group A streptococci and a virus than in patients with evidence only of infection with group...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800050159

    authors: Higgins PM

    更新日期:1992-10-01 00:00:00

  • Trends in and correlations between antibiotic consumption and resistance of Staphylococcus aureus at a tertiary hospital in China before and after introduction of an antimicrobial stewardship programme.

    abstract::The overuse of antibiotics and the rapid emergence of antibiotic resistance prompted the launch of an antimicrobial stewardship programme in 2011. This study aimed to investigate the trends and correlations between antibiotic consumption and resistance of Staphylococcus aureus in a tertiary hospital of northwest China...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818003059

    authors: Zhang D,Cui K,Wang T,Dong H,Feng W,Ma C,Dong Y

    更新日期:2018-11-16 00:00:00

  • Seroprevalence, correlates and trends of Helicobacter pylori infection in the Israeli population.

    abstract::We examined the prevalence, correlates and trends of H. pylori infection in Israel using residual sera obtained in 2007-2008 from 1466 Jewish subjects aged 0-77 years and 897 Arabs aged 0-19 years, and in 2000-2001 from 627 Jewish and 575 Arab subjects aged 0-19 years. H. pylori IgG antibodies were measured by ELISA. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811002081

    authors: Muhsen K,Cohen D,Spungin-Bialik A,Shohat T

    更新日期:2012-07-01 00:00:00

  • Assessing the impact of a nurse-delivered home dried blood spot service on uptake of testing for household contacts of hepatitis B-infected pregnant women across two London trusts.

    abstract::Despite national guidance recommending testing and vaccination of household contacts of hepatitis B-infected pregnant women, provision and uptake of this is sub-optimal. The aim of this study was to evaluate the use of in-home dried blood spot (DBS) testing to increase testing and vaccination of household contacts of ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003325

    authors: Keel P,Edwards G,Flood J,Nixon G,Beebeejaun K,Shute J,Poh J,Millar A,Ijaz S,Parry J,Mandal S,Ramsay M,Amirthalingam G

    更新日期:2016-07-01 00:00:00

  • The rise and decline in Salmonella enterica serovar Enteritidis outbreaks attributed to egg-containing foods in the United States, 1973-2009.

    abstract::Salmonella enterica causes an estimated 1 million domestically acquired foodborne illnesses annually. Salmonella enterica serovar Enteritidis (SE) is among the top three serovars of reported cases of Salmonella. We examined trends in SE foodborne outbreaks from 1973 to 2009 using Joinpoint and Poisson regression. The ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815001867

    authors: Wright AP,Richardson L,Mahon BE,Rothenberg R,Cole DJ

    更新日期:2016-03-01 00:00:00

  • Hospitalizations for respiratory syncytial virus bronchiolitis in preterm infants at

    abstract::This study was conducted during the 2008-2009 respiratory syncytial virus (RSV) season in France to compare hospitalization rates for bronchiolitis (RSV-confirmed and all types) between very preterm infants (<33 weeks' gestational age, WGA) without bronchopulmonary dysplasia and full-term infants (39-41 WGA) matched f...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0950268812001069

    authors: Gouyon JB,Rozé JC,Guillermet-Fromentin C,Glorieux I,Adamon L,DI Maio M,Miloradovich T,Anghelescu D,Pinquier D,Escande B,Elleau C

    更新日期:2013-04-01 00:00:00

  • Epidemiological analysis of Trichinella spiralis infections of foxes in Brandenburg, Germany.

    abstract::In a cross-sectional study conducted between March 1993 and February 1995, 7103 indiscriminately collected foxes were examined for Trichinella larvae. A total of 3295 serum samples were serologically investigated with an ELISA based on excretory-secretory antigen. The proportion of serologically positive animals range...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0950268899002617

    authors: Wacker K,Rodriguez E,Garate T,Geue L,Tackmann K,Selhorst T,Staubach C,Conraths FJ

    更新日期:1999-08-01 00:00:00

  • Molecular epidemiology of endemic Clostridium difficile infection.

    abstract::This is the first study to provide a comprehensive insight into the molecular epidemiology of endemic Clostridium difficile and particularly that associated with a recently recognized epidemic strain. We DNA fingerprinted all C. difficile isolates from the stools of patients with symptomatic antibiotic-associated diar...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880100557x

    authors: Fawley WN,Wilcox MH

    更新日期:2001-06-01 00:00:00

  • Lack of response of INT-407 cells to the presence of non-culturable Campylobacter jejuni.

    abstract::Many contradictory articles on the infectivity of non-culturable Campylobacter jejuni can be found. We studied the effect of non-culturable C. jejuni in an in vitro assay. To prevent the potential effect of a few culturable bacteria in the non-culturable suspension, INT-407 cells, which mimic the outer cell layer in t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807000040

    authors: Verhoeff-Bakkenes L,Hazeleger WC,Zwietering MH,De Jonge R

    更新日期:2008-10-01 00:00:00

  • Assessing the risk from emerging infections.

    abstract::Emerging infections pose a constant threat to society and can require a substantial response, thus systems to assess the threat level and inform prioritization of resources are essential. A systematic approach to assessing the risk from emerging infections to public health in the UK has been developed. This qualitativ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268809990227

    authors: Morgan D,Kirkbride H,Hewitt K,Said B,Walsh AL

    更新日期:2009-11-01 00:00:00

  • What happened at Vienna's Allgemeines Krankenhaus after Semmelweis's contract as Assistant in the First Maternity Division was terminated?

    abstract::Ignác Fülöp Semmelweis is famous for dramatically reducing puerperal mortality while he was an Assistant in Vienna's largest hospital, the Allgemeines Krankenhaus; he did this, mainly, by requiring medical personnel to disinfect their hands by washing in a chlorine solution. But Semmelweis was soon removed from his po...

    journal_title:Epidemiology and infection

    pub_type: 传,历史文章,杂志文章

    doi:10.1017/S0950268817000875

    authors: Jadraque PP,Carter KC

    更新日期:2017-07-01 00:00:00

  • Multiple sites of exposure in an outbreak of ornithosis in workers at a poultry abattoir and farm.

    abstract::Cases of ornithosis amongst workers on a rural duck abattoir and farm were notified from late 2003 to health authorities in Victoria, Australia. In May 2004 we conducted a serological survey to identify the extent of exposure to Chlamydophila psittaci amongst workers and a case control study to identify high-risk work...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026880700790X

    authors: Tiong A,Vu T,Counahan M,Leydon J,Tallis G,Lambert S

    更新日期:2007-10-01 00:00:00

  • Bancroftian filariasis in Pondicherry, south India: 2. Epidemiological evaluation of the effect of vector control.

    abstract::This article examines the evaluation of a bancroftian filariasis control programme undertaken in Pondicherry from 1981-5. Integrated vector management was applied in one half of the town, and routine operations under the national programme (larviciding and chemotherapy) continued in the comparison area. The programme ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800031095

    authors: Subramanian S,Pani SP,Das PK,Rajagopalan PK

    更新日期:1989-12-01 00:00:00

  • Applications of machine learning techniques to predict filariasis using socio-economic factors.

    abstract::Filariasis is one of the major public health concerns in India. Approximately 600 million people spread across 250 districts of India are at risk of filariasis. To predict this disease, a pilot scale study was carried out in 30 villages of Karimnagar district of Telangana from 2004 to 2007 to collect epidemiological a...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819001481

    authors: Kondeti PK,Ravi K,Mutheneni SR,Kadiri MR,Kumaraswamy S,Vadlamani R,Upadhyayula SM

    更新日期:2019-09-02 00:00:00

  • Impact of respiratory virus infection in patients with chronic chest disease.

    abstract::This study investigated the morbidity associated with respiratory virus infections in patients with well-documented chest disease, and the risk of transmission between close contacts. Patients informed the study team if they were exposed to a family member or colleague with a cold. Patients and symptomatic index cases...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800057046

    authors: Wiselka MJ,Kent J,Cookson JB,Nicholson KG

    更新日期:1993-10-01 00:00:00

  • Relationship between Legionella spp. and antibody titres at a therapeutic thermal spa in Portugal.

    abstract::The presence of Legionella spp. in the water of a Portuguese spa was ascertained during the spa season, between May and November. Simultaneously the prevalence of anti-legionella antibodies in people attending the spa was also investigated. The antibody titres of 172 randomly selected patients and 42 therapists were d...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800058143

    authors: Rocha G,Veríssimo A,Bowker R,Bornstein N,Da Costa MS

    更新日期:1995-08-01 00:00:00

  • The source of Yersinia spp. in pasteurized milk: an investigation at a dairy.

    abstract::Pasteurized bottled milk supplied by a single dairy was frequently found to be contaminated with Yersinia spp. Investigations were carried out at the dairy in an effort to pinpoint the source of these organisms. Viable counts obtained from milk bottle rinses indicated that bottle washing was often unsatisfactory, and ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800047373

    authors: Greenwood MH,Hooper WL,Rodhouse JC

    更新日期:1990-06-01 00:00:00

  • Pacific islands which escaped the 1918-1919 influenza pandemic and their subsequent mortality experiences.

    abstract::Very few Pacific islands escaped the 1918-1919 influenza pandemic. Subsequent influenza epidemics in the established colonial outposts of American Samoa and New Caledonia infected many but killed very few persons whereas the extraordinarily isolated Niue, Rotuma, Jaliut and Yule islands experienced high mortality infl...

    journal_title:Epidemiology and infection

    pub_type: 历史文章,杂志文章

    doi:10.1017/S0950268812000866

    authors: Shanks GD,Brundage JF

    更新日期:2013-02-01 00:00:00

  • Prediction of epidemic cholera due to Vibrio cholerae O1 in children younger than 10 years using climate data in Bangladesh.

    abstract::To determine if a prediction of epidemic cholera using climate data can be made, we performed autoregression analysis using the data recorded in Dhaka City, Bangladesh over a 20-year period (1983-2002) comparing the number of children aged <10 years who were infected with Vibrio cholerae O1 to the maximum and minimum ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807008175

    authors: Matsuda F,Ishimura S,Wagatsuma Y,Higashi T,Hayashi T,Faruque AS,Sack DA,Nishibuchi M

    更新日期:2008-01-01 00:00:00

  • Molecular evolution and epidemiology of four serotypes of dengue virus in Thailand from 1973 to 2007.

    abstract::Thailand was a hyper-endemic country for dengue with co-circulation of four serotypes and tens of thousands of infected cases annually. Taking into consideration the large number of local dengue virus (DENV) sequences available in GenBank, Thailand was the most ideal locality to study co-evolution of DENV. Therefore, ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812000908

    authors: Chen SP

    更新日期:2013-02-01 00:00:00

  • Regional differences in long-term cycles and seasonality of Puumala virus infections, Finland, 1995-2014.

    abstract::Puumala hantavirus (PUUV) causes haemorrhagic fever with renal syndrome in humans, an endemic disease in Finland. We aimed to study recent trends in PUUV infections in Finland, to evaluate whether there are regional differences in seasonality and long-term cycles and whether the patterns have changed over time. We ana...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000765

    authors: Sane J,Ollgren J,Makary P,Vapalahti O,Kuusi M,Lyytikäinen O

    更新日期:2016-10-01 00:00:00

  • Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation.

    abstract::Ruminants are considered the main reservoir for transmission of Coxiella burnetii (Cb) to humans. The implementation of effective control measures against Cb in ruminants requires knowledge about potential risk factors. The objectives of this study were (i) to describe the spatial distribution of Q fever-infected dair...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814003926

    authors: Nusinovici S,Frössling J,Widgren S,Beaudeau F,Lindberg A

    更新日期:2015-11-01 00:00:00

  • Determining the ideal prevention strategy for multidrug-resistance organisms in resource-limited countries: a cost-effectiveness analysis study.

    abstract::The aim of this study was to determine the most cost-effective strategy for the prevention and control of multidrug-resistant organisms (MDROs) in intensive care units (ICUs) in areas with limited health resources. The study was conducted in 12 ICUs of four hospitals. The total cost for the prevention of MDROs and the...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820001120

    authors: Wang Y,Yuan Y,Lin L,Tan X,Tan Y

    更新日期:2020-05-20 00:00:00

  • Insertion sequence IS200 fingerprinting of Salmonella typhi: an assessment of epidemiological applicability.

    abstract::When Pst I-generated digests of genomic DNA from each of the type strains of 49 of the Vi phage types of Salmonella typhi were probed with a PCR-amplified IS200 gene probe, all strains were found to possess at least 11 IS200 elements carried on fragments in the range 24.2-1.2 kb. Fourteen fingerprints were identified ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800057666

    authors: Threlfall EJ,Torre E,Ward LR,Dávalos-Pérez A,Rowe B,Gibert I

    更新日期:1994-04-01 00:00:00

  • A history of bovine tuberculosis eradication policy in Northern Ireland.

    abstract::Despite many years of state-sponsored efforts to eradicate the disease from cattle through testing and slaughter, bovine tuberculosis (bTB) is still regarded as the most important and complex of animal health challenges facing the British livestock agricultural industry. This paper provides a historical analysis of th...

    journal_title:Epidemiology and infection

    pub_type: 历史文章,杂志文章

    doi:10.1017/S0950268815000291

    authors: Robinson PA

    更新日期:2015-11-01 00:00:00

  • Estimating transmission parameters of F4+ E. coli for F4-receptor-positive and -negative piglets: one-to-one transmission experiment.

    abstract::F4+ Escherichia coli is an important agent of post-weaning diarrhoea in piglets. Piglets that express an adhesion site for F4+ E. coli in their small intestine (F4R+) shed higher numbers of F4+ E. coli than piglets lacking this site (F4R-). We hypothesized that F4R+ piglets are more infectious and more susceptible for...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002675

    authors: Geenen PL,Van der Meulen J,Bouma A,De Jong MC

    更新日期:2004-12-01 00:00:00

  • A review of invasive Haemophilus influenzae disease in the Indigenous populations of North America.

    abstract::Historically, the highest incidence rates of invasive Haemophilus influenzae disease in the world were found in North American and Australian Indigenous children. Although immunization against H. influenzae type b (Hib) led to a marked decrease in invasive Hib disease in countries where it was implemented, this diseas...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268814000405

    authors: Tsang RS,Bruce MG,Lem M,Barreto L,Ulanova M

    更新日期:2014-07-01 00:00:00

  • Molecular typing of Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolates from endemic and epidemic nosocomial infections.

    abstract::Ribotype, biotype and resistance phenotype were used to characterize 37 Acinetobacter baumannii-A. calcoaceticus complex isolates responsible for nosocomial infections in Buenos Aires. Nineteen isolates were recovered from endemic infections at 2 hospitals and 18 represent an intensive care unit outbreak that occurred...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800051979

    authors: Ratto P,Sordelli DO,Abeleira E,Torrero M,Catalano M

    更新日期:1995-02-01 00:00:00

  • Outbreaks of infection with methicillin-resistant Staphylococcus aureus on neonatal and burns units of a new hospital.

    abstract::Multiple introductions of methicillin-resistant Staphylococcus aureus (MRSA) strains occurred to a new hospital in Hong Kong. Two years of clinical microbiological surveillance of the resulting outbreaks was combined with laboratory investigation by phage and antibiogram typing, and plasmid profiling. The outbreaks on...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800047828

    authors: Farrington M,Ling J,Ling T,French GL

    更新日期:1990-10-01 00:00:00