Abstract:
:Despite national guidance recommending testing and vaccination of household contacts of hepatitis B-infected pregnant women, provision and uptake of this is sub-optimal. The aim of this study was to evaluate the use of in-home dried blood spot (DBS) testing to increase testing and vaccination of household contacts of hepatitis B-infected pregnant women as an alternative approach to conventional primary-care follow-up. The study was conducted across two London maternity trusts (North Middlesex and Newham). All hepatitis B surface antigen-positive pregnant women identified through these trusts were eligible for inclusion. The intervention of in-home DBS testing for household contacts was introduced at North Middlesex Trust from November 2010 to December 2011. Data on testing and vaccination uptake from GP records across the two trusts were compared between baseline (2009) and intervention (2010-2011) periods. In-home DBS service increased testing uptake for all ages (P < 0·001) with the biggest impact seen in partners, where testing increased from 30·3% during the baseline period to 96·6% during the intervention period in North Middlesex Trust. Although impact on vaccine uptake was less marked, improvements were observed for adults. The provision of nurse-led home-based DBS may be useful in areas of high prevalence.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Keel P,Edwards G,Flood J,Nixon G,Beebeejaun K,Shute J,Poh J,Millar A,Ijaz S,Parry J,Mandal S,Ramsay M,Amirthalingam Gdoi
10.1017/S0950268815003325subject
Has Abstractpub_date
2016-07-01 00:00:00pages
2087-97issue
10eissn
0950-2688issn
1469-4409pii
S0950268815003325journal_volume
144pub_type
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