An outbreak of Legionnaires' disease in Gloucester.

Abstract:

:Fourteen people living in or near the city of Gloucester fell ill with Legionnaires' disease caused by Legionella pneumophila serogroup (SG) 1 between 27 August and 27 October 1986. Another patient had fallen ill on 30 May. Nine of the 15 were diagnosed retrospectively during a case finding exercise. There were three deaths. Three cases of Pontiac fever were also diagnosed. The source was probably one or more wet cooling towers. Nineteen premises in the city with such towers were identified, and three just outside Gluocester. Samples from 11 of the 22 premises grew Legionella spp.; from nine of these L. pneumophila SG 1 (Pontiac) was isolated. The efficacy of regular addition of biocide in addition to hypochlorite added at the time of disinfection in inhibiting the growth of Legionella spp. was demonstrated. A survey of patients' movements during their likely incubation period showed that there was no single building that all patients had visited, but there were two areas of the city which nearly all had visited or passed through by car. A case-control study demonstrated an association with one of these areas. Cooling towers near both areas may have been sources but the evidence is insufficient to incriminate any single one. The unexpected finding of L. pneumophila SG 1 (Pontiac) in nine towers supports the hypothesis that there may have been multiple sources. Cooling towers may have been contaminated by mains water or by drift from other towers.

journal_name

Epidemiol Infect

authors

Hunt DA,Cartwright KA,Smith MC,Middleton J,Bartlett CL,Lee JV,Dennis PJ,Harper D

doi

10.1017/s0950268800048767

subject

Has Abstract

pub_date

1991-08-01 00:00:00

pages

133-41

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

107

pub_type

杂志文章
  • Time-course of antibody responses against Coxiella burnetii following acute Q fever.

    abstract::Large outbreaks of Q fever in The Netherlands have provided a unique opportunity for studying longitudinal serum antibody responses in patients. Results are presented of a cohort of 344 patients with acute symptoms of Q fever with three or more serum samples per patient. In all these serum samples IgM and IgG against ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268812000404

    authors: Teunis PF,Schimmer B,Notermans DW,Leenders AC,Wever PC,Kretzschmar ME,Schneeberger PM

    更新日期:2013-01-01 00:00:00

  • Preferential association of the heat-stable enterotoxin gene (stn) with environmental strains of Vibrio cholerae belonging to the O14 serogroup.

    abstract::Toxigenic Vibrio cholerae O1 and O139 serogroups have the capacity of causing epidemic and pandemic cholera but are infrequently found in the environment. The other serogroups are abundant in aquatic environments but do not possess the virulence genes necessary for causing the disease. Of the 559 environmental strains...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007392

    authors: Sarkar B,Bhattacharya T,Ramamurthy T,Shimada T,Takeda Y,Balakrish Nair G

    更新日期:2002-10-01 00:00:00

  • Hospitalization rates associated with hepatitis B and HIV co-infection, age and sex in a population-based cohort of people diagnosed with hepatitis C.

    abstract::To determine the extent age, sex and co-infection affect morbidity in people infected with hepatitis C virus (HCV), we performed a population-based study linking HCV notifications in New South Wales, Australia with their hospital (July 2000 to June 2006), hepatitis B virus (HBV) and HIV notification, and death records...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881000258X

    authors: Gidding HF,Amin J,Dore GJ,Law MG

    更新日期:2011-08-01 00:00:00

  • Estimating transmission parameters of F4+ E. coli for F4-receptor-positive and -negative piglets: one-to-one transmission experiment.

    abstract::F4+ Escherichia coli is an important agent of post-weaning diarrhoea in piglets. Piglets that express an adhesion site for F4+ E. coli in their small intestine (F4R+) shed higher numbers of F4+ E. coli than piglets lacking this site (F4R-). We hypothesized that F4R+ piglets are more infectious and more susceptible for...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268804002675

    authors: Geenen PL,Van der Meulen J,Bouma A,De Jong MC

    更新日期:2004-12-01 00:00:00

  • Design and analysis of small-scale transmission experiments with animals.

    abstract::Interactions between pathogens and hosts at the population level should be considered when studying the effectiveness of control measures for infectious diseases. The advantage of doing transmission experiments compared to field studies is that they offer a controlled environment in which the effect of a single factor...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026880600673X

    authors: Velthuis AG,Bouma A,Katsma WE,Nodelijk G,De Jong MC

    更新日期:2007-02-01 00:00:00

  • The changing epidemiological pattern of hepatitis A in England and Wales.

    abstract::Sera from an age-stratified sample of 4188 individuals, submitted for diagnostic purposes to 15 public health laboratories in England and Wales in 1996, were tested for hepatitis A antibody. The serological profiles were consistent with declining incidence in the past. This hypothesis was tested by comparing the serol...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880200701x

    authors: Morris MC,Gay NJ,Hesketh LM,Morgan-Capner P,Miller E

    更新日期:2002-06-01 00:00:00

  • Multistate foodborne disease outbreaks associated with raw tomatoes, United States, 1990-2010: a recurring public health problem.

    abstract::We examined multistate outbreaks attributed to raw tomatoes in the United States from 1990 to 2010. We summarized the demographic and epidemiological characteristics of 15 outbreaks resulting in 1959 illnesses, 384 hospitalizations, and three deaths. Most (80%) outbreaks were reported during 2000-2010; 73% occurred Ma...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002167

    authors: Bennett SD,Littrell KW,Hill TA,Mahovic M,Behravesh CB

    更新日期:2015-05-01 00:00:00

  • Pigs with highly prevalent antibodies to human coronavirus and swine haemagglutinating encephalomyelitis virus in the Tohoku District of Japan.

    abstract::From 1985 to 1988, a total of 2496 swine sera from 60 farms in the Tohoku District of the Honshu Island of Japan were examined for antibodies to swine haemagglutinating encephalomyelitis virus (HEV), human coronavirus (HCV) and bovine coronavirus (BCV) by haemagglutination-inhibition (HI) test. Antibodies to HEV 67N s...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899002332

    authors: Hirano N,Suzuki Y,Haga S

    更新日期:1999-06-01 00:00:00

  • Outbreak of hospital-acquired gastroenteritis and invasive infection caused by Listeria monocytogenes, Finland, 2012.

    abstract::During one week in July 2012, two patients from the same ward at the municipal hospital in Vaasa, Finland, were diagnosed with septicaemia caused by Listeria monocytogenes. An outbreak investigation revealed eight concomitant cases of febrile gastroenteritis caused by L. monocytogenes on the same ward. Median age of t...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815002563

    authors: Jacks A,Pihlajasaari A,Vahe M,Myntti A,Kaukoranta SS,Elomaa N,Salmenlinna S,Rantala L,Lahti K,Huusko S,Kuusi M,Siitonen A,Rimhanen-Finne R

    更新日期:2016-10-01 00:00:00

  • Time to Rt < 1 for COVID-19 public health lockdown measures.

    abstract::The epidemiological target of lockdowns is to drive down the effective reproduction number (Rt) to less than 1. A key unknown is the duration that lockdowns need to be in place to achieve this and which lockdown measures are effective. Daily number of laboratory confirmed community coronavirus 2019 cases were extracte...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268820002964

    authors: Yung CF,Saffari E,Liew C

    更新日期:2020-12-09 00:00:00

  • The use of the case-crossover design in a continuous common source food-borne outbreak.

    abstract::When applicable, case-crossover studies may be quicker and cheaper to complete than case-control studies. Because time is a major issue in outbreak investigations, we evaluated the interest of this design during a continuous common source food-borne outbreak of salmonellosis for which the vehicle (hamburgers) was also...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268803001006

    authors: Haegebaert S,Duche L,Desenclos JC

    更新日期:2003-10-01 00:00:00

  • Regional differences in long-term cycles and seasonality of Puumala virus infections, Finland, 1995-2014.

    abstract::Puumala hantavirus (PUUV) causes haemorrhagic fever with renal syndrome in humans, an endemic disease in Finland. We aimed to study recent trends in PUUV infections in Finland, to evaluate whether there are regional differences in seasonality and long-term cycles and whether the patterns have changed over time. We ana...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816000765

    authors: Sane J,Ollgren J,Makary P,Vapalahti O,Kuusi M,Lyytikäinen O

    更新日期:2016-10-01 00:00:00

  • Social contacts of school children and the transmission of respiratory-spread pathogens.

    abstract::Empirical data about contact frequencies of children is needed for estimating parameters in mathematical modelling studies that investigate the effect of targeting influenza intervention to children. A survey about the social contacts of school children was conducted in a primary school in Germany. The distribution of...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009181

    authors: Mikolajczyk RT,Akmatov MK,Rastin S,Kretzschmar M

    更新日期:2008-06-01 00:00:00

  • Food poisoning in hospitals in Scotland, 1978-87.

    abstract::During the 10-year period 1978-87 there were 48 outbreaks of food poisoning in Scottish hospitals affecting a total of 2287 persons of whom 12 died. This compared with 50 outbreaks during the previous 5 years (1973-77) when over 1500 persons and 7 deaths were recorded. Although the incidence of outbreaks has decreased...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880002954x

    authors: Collier PW,Sharp JC,MacLeod AF,Forbes GI,Mackay F

    更新日期:1988-12-01 00:00:00

  • Putative household outbreaks of campylobacteriosis typically comprise single MLST genotypes.

    abstract::During a 15-month period in Scotland a small but important number of human Campylobacter cases (3·2%) arose from 91 putative household outbreaks. Of the 26 outbreaks with known strain composition, 89% were composed of the same MLST which supports the potential use of MLST in public health epidemiology. The number of c...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810001457

    authors: Rotariu O,Smith-Palmer A,Cowden J,Bessell PR,Innocent GT,Reid SW,Matthews L,Dallas J,Ogden ID,Forbes KJ,Strachan NJ

    更新日期:2010-12-01 00:00:00

  • Incomplete sanitation of a meat grinder and ingestion of raw ground beef: contributing factors to a large outbreak of Salmonella typhimurium infection.

    abstract::Consumers in the United States continue to eat raw or undercooked foods of animal origin despite public health warnings following several well-publicized outbreaks. We investigated an outbreak of Salmonella serotype Typhimurium infection in 158 patients in Wisconsin during the 1994 Christmas holiday period. To determi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268897007851

    authors: Roels TH,Frazak PA,Kazmierczak JJ,Mackenzie WR,Proctor ME,Kurzynski TA,Davis JP

    更新日期:1997-10-01 00:00:00

  • Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs.

    abstract::Foot-and-mouth disease virus (FMDV) can be spread by a variety of mechanisms, including wind. Simulation models, developed to predict the risk of airborne spread, have played an important part in decision making in some outbreaks. The amount of airborne virus excreted as well as the minimal infectious dose (MID) of FM...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801006501

    authors: Alexandersen S,Donaldson AI

    更新日期:2002-04-01 00:00:00

  • Herpes simplex virus encephalitis in Peru: a multicentre prospective study.

    abstract::Herpes simplex virus (HSV) is one of the most commonly identified infectious aetiologies of encephalitis in North America and Europe. The epidemiology of encephalitis beyond these regions, however, is poorly defined. During 2009-2012 we enrolled 313 patients in a multicentre prospective study of encephalitis in Peru, ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0950268815003222

    authors: Montano SM,Mori N,Nelson CA,Ton TG,Celis V,Ticona E,Sihuincha M,Tilley DH,Kochel T,Zunt JR,Meningoencephalitis Working Group.

    更新日期:2016-06-01 00:00:00

  • Daily shedding dynamics of E. coli O157 in an Australian grass-fed beef herd.

    abstract::This study aimed to describe the diurnal shedding dynamics of Escherichia coli O157 in cattle managed on pasture. The purpose was to identify the value of a single measurement for predicting the shedding status on subsequent days. Over a 14-day period, 24 beef cows with known E. coli O157 shedding status were sampled ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816001588

    authors: Lammers GA,Jordan D,McCONNEL CS,Heller J

    更新日期:2016-10-01 00:00:00

  • Evaluating vaccination strategies to control foot-and-mouth disease: a model comparison study.

    abstract::Simulation models can offer valuable insights into the effectiveness of different control strategies and act as important decision support tools when comparing and evaluating outbreak scenarios and control strategies. An international modelling study was performed to compare a range of vaccination strategies in the co...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814001927

    authors: Roche SE,Garner MG,Sanson RL,Cook C,Birch C,Backer JA,Dube C,Patyk KA,Stevenson MA,Yu ZD,Rawdon TG,Gauntlett F

    更新日期:2015-04-01 00:00:00

  • Molecular typing of Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolates from endemic and epidemic nosocomial infections.

    abstract::Ribotype, biotype and resistance phenotype were used to characterize 37 Acinetobacter baumannii-A. calcoaceticus complex isolates responsible for nosocomial infections in Buenos Aires. Nineteen isolates were recovered from endemic infections at 2 hospitals and 18 represent an intensive care unit outbreak that occurred...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800051979

    authors: Ratto P,Sordelli DO,Abeleira E,Torrero M,Catalano M

    更新日期:1995-02-01 00:00:00

  • Projections of increased and decreased dengue incidence under climate change.

    abstract::Dengue is the world's most prevalent mosquito-borne disease, with more than 200 million people each year becoming infected. We used a mechanistic virus transmission model to determine whether climate warming would change dengue transmission in Australia. Using two climate models each with two carbon emission scenarios...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881600162X

    authors: Williams CR,Mincham G,Faddy H,Viennet E,Ritchie SA,Harley D

    更新日期:2016-10-01 00:00:00

  • Animal agriculture exposures among Minnesota residents with zoonotic enteric infections, 2012-2016.

    abstract::Prospective, population-based surveillance to systematically ascertain exposures to food production animals or their environments among Minnesota residents with sporadic, domestically acquired, laboratory-confirmed enteric zoonotic pathogen infections was conducted from 2012 through 2016. Twenty-three percent (n = 170...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819002309

    authors: Klumb CA,Scheftel JM,Smith KE

    更新日期:2020-03-16 00:00:00

  • Relationship between Legionella spp. and antibody titres at a therapeutic thermal spa in Portugal.

    abstract::The presence of Legionella spp. in the water of a Portuguese spa was ascertained during the spa season, between May and November. Simultaneously the prevalence of anti-legionella antibodies in people attending the spa was also investigated. The antibody titres of 172 randomly selected patients and 42 therapists were d...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800058143

    authors: Rocha G,Veríssimo A,Bowker R,Bornstein N,Da Costa MS

    更新日期:1995-08-01 00:00:00

  • An outbreak of hepatitis A amongst injecting drug users.

    abstract::This descriptive study investigated an outbreak of hepatitis A virus (HAV) infection among injecting drug users (IDUs) and their contacts. Twenty-seven cases of acute HAV infection were identified in a 5-month period. Connections with the local injecting drug using (IDU) population were established for 25 of the cases...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268801006185

    authors: O'Donovan D,Cooke RP,Joce R,Eastbury A,Waite J,Stene-Johansen K

    更新日期:2001-12-01 00:00:00

  • Multi-country outbreak of Salmonella enteritidis infection linked to the international ice hockey tournament.

    abstract::In April 2015, Finnish public health authorities alerted European Union member states of a possible multi-country Salmonella enteritidis outbreak linked to an international youth ice-hockey tournament in Latvia. The European Centre for Disease Prevention and Control (ECDC), Finnish and Latvian authorities initiated an...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001212

    authors: Pärn T,Dahl V,Lienemann T,Perevosčikovs J,De Jong B

    更新日期:2017-08-01 00:00:00

  • Community-associated methicillin-resistant Staphylococcus aureus infections at an Army training installation.

    abstract::To assess the burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in a high-risk population, the monthly incidence of laboratory-confirmed MRSA in service members/trainees stationed at Fort Benning, Georgia, USA without hospitalization or surgery documented 30 days prior to infection w...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810000142

    authors: Morrison-Rodriguez SM,Pacha LA,Patrick JE,Jordan NN

    更新日期:2010-05-01 00:00:00

  • Surgical site infection following cesarean section in a general hospital in Kuwait: trends and risk factors.

    abstract::Surgical site infections (SSI) are a significant cause of post-surgical morbidity and mortality. The objectives of this study were to determine the prevalence of SSI and identify risk factors for infections following cesarean section (CS). A prospective study of SSI after CS was carried out from January 2014 to Decemb...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268819001675

    authors: Alfouzan W,Al Fadhli M,Abdo N,Alali W,Dhar R

    更新日期:2019-10-10 00:00:00

  • Epidemiology of shigellosis in Teknaf, a coastal area of Bangladesh: a 10-year survey.

    abstract::The epidemiological data on shigellosis in Teknaf, a coastal area of Bangladesh, were reviewed for a 10-year period (1975-84). Certain similarities and differences were observed in the epidemiology of the disease in Teknaf when compared with urban Dhaka and rural Matlab. Similarities included: round-the-year infection...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800047622

    authors: Hossain MA,Albert MJ,Hasan KZ

    更新日期:1990-08-01 00:00:00

  • Deviating from IDSA treatment guidelines for non-purulent skin infections increases the risk of treatment failure in emergency department patients.

    abstract::The Infectious Disease Society of America (IDSA) publishes guidelines regularly for the management of skin and soft tissue infections; however, the extent to which practice patterns follow these guidelines and if this can affect treatment failure rates is unknown. We observed the treatment failure rates from a multice...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268818003291

    authors: Haran JP,Wilsterman E,Zeoli T,Goulding M,McLendon E,Clark MA

    更新日期:2018-12-05 00:00:00