Characteristics and TB treatment outcomes in TB patients with viral hepatitis, New York City, 2000-2010.

Abstract:

:Literature surrounding the burden of and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in persons with tuberculosis (TB) disease remains limited and focused on populations outside the USA. Cross-matched New York City (NYC) TB and viral hepatitis surveillance data were used to estimate the proportion of NYC adults diagnosed with TB from 2000 to 2010 with a report of viral hepatitis infection and to describe the impact of viral hepatitis infection on TB treatment completion and death. For 9512 TB patients, HCV infection was reported in 4.2% and HBV infection in 3.7%; <1% of TB patients had both HCV and HBV infection. The proportion of TB patients with HCV infection to die before TB treatment completion was larger than in TB patients without a viral hepatitis report (21% vs. 9%); this association remained when stratified by HIV status. There was no significant difference in death before treatment completion for TB patients with HBV infection compared to TB patients without a viral hepatitis report when stratified by HIV status. These findings reinforce the importance of hepatitis testing and providing additional support to TB patients with viral hepatitis infection.

journal_name

Epidemiol Infect

authors

Bushnell G,Stennis NL,Drobnik AM,Proops DC,Ahuja SD,Bornschlegel K,Fuld J

doi

10.1017/S0950268814002970

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

1972-81

issue

9

eissn

0950-2688

issn

1469-4409

pii

S0950268814002970

journal_volume

143

pub_type

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