Abstract:
:To investigate the joint association of patient and strain characteristics with the outcome of meningococcal disease (MD), data were collected on 563 consecutive cases of MD reported between 1989 and 1990 in The Netherlands. The meningococcal isolates were characterized with regard to their surface characteristics. Sequelae occurred in 8.5% of the patients, and were only associated with the presence of bacteraemia. The case-fatality rate was 7.7%. Infants aged < or = 5 months and patients in the age-groups of 10-19 years and > or = 50 years had an increased risk for a fatal outcome compared with children from 6 months to 9 years old (Odds Ratios [ORs]: 5.1, 3.4 and 9.8, respectively). The OR for females versus males was 2.3. The ORs for patients with bacteraemia, or a combination of bacteraemia and meningitis, compared with meningitic patients, were 2.3 and 3.1. Meningococcal strain characteristics did not influence the case-fatality rate substantially. In conclusion, host factors were found to be determinants for a fatal outcome of MD in The Netherlands from 1989 to 1990.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Scholten RJ,Bijlmer HA,Valkenburg HA,Dankert Jdoi
10.1017/s0950268800057472subject
Has Abstractpub_date
1994-02-01 00:00:00pages
115-24issue
1eissn
0950-2688issn
1469-4409journal_volume
112pub_type
杂志文章abstract::This study was conducted during the 2008-2009 respiratory syncytial virus (RSV) season in France to compare hospitalization rates for bronchiolitis (RSV-confirmed and all types) between very preterm infants (<33 weeks' gestational age, WGA) without bronchopulmonary dysplasia and full-term infants (39-41 WGA) matched f...
journal_title:Epidemiology and infection
pub_type: 杂志文章,多中心研究
doi:10.1017/S0950268812001069
更新日期:2013-04-01 00:00:00
abstract::The spread of COVID-19 is recent in India, which has within 4 months caused over 190 000 infections, as of 1 June 2020, despite four stringent lockdowns. With the current rate of the disease transmission in India, which is home to over 1.35 billion people, the infection spread is predicted to be worse than the USA in ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268820001776
更新日期:2020-08-11 00:00:00
abstract::We systematically investigated risk factors for typhoid fever in Kamalapur, a poor urban area of Bangladesh, to inform targeted public health measures for its control. We interviewed patients with typhoid fever and two age-matched controls per case about exposures during the 14 days before the onset of illness. The mu...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268806007114
更新日期:2007-04-01 00:00:00
abstract::We assessed if there has been a decline in the median number of reported lifetime sexual partners in Kenya following the AIDS epidemic. The Wilcoxon rank-sum test was used to compare the median and interquartile range (IQR) of the number of lifetime sexual partners for men aged 20-54 years in the 1993 and 2008 Kenyan ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881500165X
更新日期:2016-02-01 00:00:00
abstract::During the period 2000-2003, wild grey foxes (Urocyon cinereoargenteus) in northern Colombia became infected with rabies. In order to derive phylogenetic relationships between rabies viruses isolated in foxes, dogs and humans in this region, 902 nt cDNA fragments containing the G-L intergenic region and encoding the c...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268805003699
更新日期:2005-06-01 00:00:00
abstract::Pertussis morbidity is highest in infants too young to be fully protected by routine vaccination schedules. Alternate vaccine strategies are required to maximise protection in this age-group. To understand baseline pertussis epidemiology prior to the introduction of the maternal pertussis vaccination program in 2014, ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268817002722
更新日期:2018-01-01 00:00:00
abstract::The epidemiological target of lockdowns is to drive down the effective reproduction number (Rt) to less than 1. A key unknown is the duration that lockdowns need to be in place to achieve this and which lockdown measures are effective. Daily number of laboratory confirmed community coronavirus 2019 cases were extracte...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268820002964
更新日期:2020-12-09 00:00:00
abstract::SUMMARY This study assesses the contribution of different sources of human campylobacteriosis in Denmark using two different source-attribution approaches. In total, 794 non-human isolates and 406 isolates from human cases (domestic, travel related, and cases with unknown travel history) were collected. Isolates were ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813002719
更新日期:2014-08-01 00:00:00
abstract::Individuals developing an HIV seroconversion illness may experience rapid disease progression. Information on seroconversion illness is rarely collected in most cohort studies, thus the aim of this study was to assess the value of the HIV test interval (the time between last negative and first positive HIV tests) as a...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268801005805
更新日期:2001-08-01 00:00:00
abstract::The efficacy of interferon A (rIFN-alpha 2A), an Escherichia coli-derived interferon, in the prophylaxis of acute upper respiratory tract infection, was evaluated in a community-based double-blind placebo-controlled study in the Australian winter of 1985. The trial population of 412 healthy volunteers (190 males and 2...
journal_title:Epidemiology and infection
pub_type: 临床试验,杂志文章
doi:10.1017/s0950268800029484
更新日期:1988-12-01 00:00:00
abstract::The prevalence of Escherichia coli O157 displays striking variability across the Scottish cattle population. On 78% of farms, in a cross-sectional survey of 952, no shedding of E. coli O157 was detected, but on a small proportion, approximately 2%, very high prevalences of infection were found (with 90-100% of pats sa...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805004590
更新日期:2006-02-01 00:00:00
abstract::Escherichia coli O157 infections cause an estimated 60 deaths and 73 000 illnesses annually in the United States. A marked summer peak in incidence is largely unexplained. We investigated an outbreak of E. coli O157 infections at an agricultural fair in Ohio and implicated consumption of beverages made with fairground...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001237
更新日期:2003-12-01 00:00:00
abstract::The prevalence of hepatitis B virus markers in the adult Swedish population was investigated according to age, sex, origin and demographic stratum. Sera were collected from 3382 persons in 1990-1. The sera were selected on a statistical basis considered to be representative of the Swedish population from adults aged >...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268897007838
更新日期:1997-10-01 00:00:00
abstract::Among the known human rotavirus serotypes, types G1-G4 are ubiquitous and account for >80% of global human rotavirus strains. Since 1994 an increase in reports of G9 serotype isolates has been observed in both developed and developing countries. In the winter season of 1999-2000 we detected the appearance of G9 rotavi...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268803001602
更新日期:2004-04-01 00:00:00
abstract::This study determined the genetic background of virulence and resistance genes of MRSA ST398 in Austria. From 2004 up to 2008 a total of 41 human isolates of MRSA ST398 were investigated for virulence and resistance gene patterns using DNA microarray chip analysis. Highly similar virulence gene profiles were found in ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812001343
更新日期:2013-04-01 00:00:00
abstract::Seasonal peaks in both human campylobacter infections and poultry isolates have been observed in several European countries but remain unexplained. We compared weekly data on human campylobacter infections with thermophilic Campylobacter isolation rates from fresh, retail chicken samples (n = 514) purchased weekly in ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268804003188
更新日期:2005-02-01 00:00:00
abstract::The objective of this study was to investigate the genetic diversity of methicillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC) 398 using pulsed-field gel electrophoresis (PFGE). Dust and pigs at five age groups were sampled in six Danish MRSA-positive pig farms. MRSA CC398 was isolated from 284 of the ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811002391
更新日期:2012-10-01 00:00:00
abstract::Following isolation of Legionella pneumophila from a special dental station water circuit, used primarily to cool high-speed dental drills which produce fine aerosols, a case finding and environmental survey was undertaken. Widespread colonization of the dental stations was found and the results suggested that amplifi...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s095026880006698x
更新日期:1987-08-01 00:00:00
abstract::Early, conforming antibiotic treatment in elderly patients hospitalised for community-acquired pneumonia (CAP) is a key factor in the prognosis and mortality. The objective was to examine whether empirical antibiotic treatment was conforming according to the Spanish Society of Pulmonology and Thoracic Surgery guidelin...
journal_title:Epidemiology and infection
pub_type: 杂志文章,多中心研究
doi:10.1017/S0950268818002121
更新日期:2018-10-01 00:00:00
abstract::This study investigated whether exposure to inactivated rabbit haemorrhagic disease virus (RHDV) can produce an antigenic response in rabbits and protect them from a subsequent challenge with virulent virus. The aim was to determine if the spreading of baits containing RHDV, which is a common management practice in Ne...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268805003754
更新日期:2005-08-01 00:00:00
abstract::Current methods of control recruitment for case-control studies can be slow (a particular issue for outbreak investigations), resource-intensive and subject to a range of biases. Commercial market panels are a potential source of rapidly recruited controls. Our study evaluated food exposure data from these panel contr...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268819000219
更新日期:2019-01-01 00:00:00
abstract::Influenza vaccine effectiveness (VE) wanes over the course of a temperate climate winter season but little data are available from tropical countries with year-round influenza virus activity. In Singapore, a retrospective cohort study of adults vaccinated from 2013 to 2017 was conducted. Influenza vaccine failure was ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268820002952
更新日期:2020-12-02 00:00:00
abstract::This study investigated the clinical characteristics of, and outcomes and risk factors for hospital mortality of 390 patients admitted with severe sepsis or septic shock in an intensive care unit (ICU). Prospectively collected data from patients collected between 1 July 2004 and 30 June 2006 were analysed. Overall hos...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809002027
更新日期:2009-09-01 00:00:00
abstract::The genetic relationships between various serotypes and serogroups of meningococcal strains were investigated by restriction fragment-length polymorphism (RFLP) analysis using a number of random DNA probes and a probe containing a truncated copy of the meningococcal insertion sequence IS1106. The data were used to est...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800050184
更新日期:1992-10-01 00:00:00
abstract::Varicella is a common and highly contagious childhood disease which impacts the public worldwide. Hong Kong children can only be vaccinated against the disease in private practice. The varicella vaccination rate of local children in preschool is uncertain. Therefore a cross-sectional kindergarten-based parent-administ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813001994
更新日期:2014-05-01 00:00:00
abstract::Between January and March 1992, 361 faecal specimens were collected from the healthy black population in the Transvaal Province of South Africa. Each specimen was examined for the prevalence of antimicrobial resistance in commensal bacteria. Volunteers, from both rural and urban dwellings, were divided into four age g...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800056922
更新日期:1993-10-01 00:00:00
abstract::Very few Pacific islands escaped the 1918-1919 influenza pandemic. Subsequent influenza epidemics in the established colonial outposts of American Samoa and New Caledonia infected many but killed very few persons whereas the extraordinarily isolated Niue, Rotuma, Jaliut and Yule islands experienced high mortality infl...
journal_title:Epidemiology and infection
pub_type: 历史文章,杂志文章
doi:10.1017/S0950268812000866
更新日期:2013-02-01 00:00:00
abstract::We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investiga...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268820001521
更新日期:2020-07-07 00:00:00
abstract::Ribotype, biotype and resistance phenotype were used to characterize 37 Acinetobacter baumannii-A. calcoaceticus complex isolates responsible for nosocomial infections in Buenos Aires. Nineteen isolates were recovered from endemic infections at 2 hospitals and 18 represent an intensive care unit outbreak that occurred...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800051979
更新日期:1995-02-01 00:00:00
abstract::Annual periodicities of reported chickenpox cases have been observed in several countries. Of these, Japan has reported a two-peaked, bimodal annual cycle of reported chickenpox cases. This study investigated the possible underlying association of the bimodal cycle observed in the surveillance data of reported chicken...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881400363X
更新日期:2015-09-01 00:00:00