Risk factors for typhoid fever in a slum in Dhaka, Bangladesh.

Abstract:

:We systematically investigated risk factors for typhoid fever in Kamalapur, a poor urban area of Bangladesh, to inform targeted public health measures for its control. We interviewed patients with typhoid fever and two age-matched controls per case about exposures during the 14 days before the onset of illness. The municipal water supply was used by all 41 cases and 81of 82 controls. In multivariate analysis, drinking unboiled water at home was a significant risk factor [adjusted odds ratio (aOR) 12.1, 95% CI 2.2-65.6]. Twenty-three (56%) cases and 21 (26%) controls reported that water from the primary source was foul-smelling (aOR 7.4, 95% CI 2.1-25.4). Eating papaya was associated with illness (aOR 5.2, 95% CI 1.2-22.2). Using a latrine for defecation was significantly protective (aOR 0.1, 95% CI 0.02-0.9). Improved chlorination of the municipal water supply or disinfecting drinking water at the household level may dramatically reduce the risk of typhoid fever in Kamalapur. The protective effect of using latrines, particularly among young children, should be investigated further.

journal_name

Epidemiol Infect

authors

Ram PK,Naheed A,Brooks WA,Hossain MA,Mintz ED,Breiman RF,Luby SP

doi

10.1017/S0950268806007114

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

458-65

issue

3

eissn

0950-2688

issn

1469-4409

pii

S0950268806007114

journal_volume

135

pub_type

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