Abstract:
:During the period 2000-2003, wild grey foxes (Urocyon cinereoargenteus) in northern Colombia became infected with rabies. In order to derive phylogenetic relationships between rabies viruses isolated in foxes, dogs and humans in this region, 902 nt cDNA fragments containing the G-L intergenic region and encoding the cytoplasmic domain of protein G and a fragment of protein L were obtained by RT-PCR, sequenced and compared. Phylogenetic analysis showed that rabies viruses isolated in foxes, dogs and humans belonged to a single genetic variant. Speculative analysis together with epidemiological data indicated that rabies in foxes may have been due to contact with rabid dogs. Rabies transmission between dogs, wild foxes and humans may happen in natural conditions in northern Colombia. This finding is the first to suggest dog-to-fox rabies transmission in South America, and provides another example of dog rabies variants being able to successfully colonize wildlife hosts.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Páez A,Saad C,Núñez C,Bóshell Jdoi
10.1017/s0950268805003699subject
Has Abstractpub_date
2005-06-01 00:00:00pages
529-36issue
3eissn
0950-2688issn
1469-4409journal_volume
133pub_type
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