Prevalence of hepatitis B anti-core antibody in the Republic of Ireland.

Abstract:

:The aim of this study was to estimate the prevalence of hepatitis B exposure in the population of the Republic of Ireland, by measuring the prevalence of hepatitis B anti-core antibody in oral fluid collected by postal survey. A random multi-stage stratified sample of Irish households was obtained, using the Irish electoral register as the sampling frame. A total of 962 households were selected, and a household response rate of 60.4% was achieved. Oral fluid specimens totalling 1714 were tested for antibody to hepatitis B core antigen (anti-HBc), using an Immune Capture Enzyme Immuno-Assay. Five specimens (0.29%) were found to contain anti-HBc. Adjusting for study design, the estimated anti-HBc prevalence in the Republic of Ireland is 0.51%. This study demonstrates that self-collection of oral fluid samples is acceptable to the public, and based upon the data generated, that the Republic of Ireland has a low prevalence of hepatitis B infection.

journal_name

Epidemiol Infect

authors

O'Connell T,Thornton L,O'Flanagan D,Staines A,Connell J,Dooley S,McCormack G

doi

10.1017/s095026880000491x

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

701-4

issue

3

eissn

0950-2688

issn

1469-4409

journal_volume

125

pub_type

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