Abstract:
:To describe the features of hepatitis B virus (HBV) infection in Madagascar, a randomized sero-epidemiological survey was undertaken in the general population > or = 1 year old of two provinces which represents 45% of the total population. In the 921 sera tested, the prevalence of HBV markers was 20.5% for HBsAg, 38.2% for anti-HBc and 6.9% for HBeAg. HBsAg and anti-HBc prevalence rates were significantly higher in males. A large difference in HBsAg prevalence was observed between urban (5.3%) and rural areas (26.0%). The same contrast in prevalence was noticed for the other HBV markers. In rural areas, HBV infection was more frequently acquired early in infancy, which suggests predominantly perinatal or postnatal transmission. The presence of HBV markers was not significantly associated with a history of blood transfusion, surgery or parenteral injection. High infectivity carriers represented 5.3% and the overall frequency of chronic carriers was 10.4%. These results place Madagascar among areas of high endemicity.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Boisier P,Rabarijaona L,Piollet M,Roux JF,Zeller HGdoi
10.1017/s0950268800001229subject
Has Abstractpub_date
1996-08-01 00:00:00pages
133-7issue
1eissn
0950-2688issn
1469-4409journal_volume
117pub_type
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