Molecular epidemiology of recent United Kingdom isolates of Neisseria meningitidis serogroup C.

Abstract:

:The genomes of 34 recent United Kingdom isolates of Neisseria meningitidis serogroup C were examined by restriction enzyme digestion and by conventional and pulsed-field gel electrophoresis (PFGE). Strains were assigned to groups on the basis of the Dice similarity coefficient; strains with values of > 92% were considered to be clonally related. Twelve clones were identified by PFGE. Strains of two clonal groups predominated. Restriction endonuclease analyses using the 'high frequency cleavage' endonuclease Stu I and conventional electrophoresis gave 11 groups; in general it had lower resolving power than PFGE.

journal_name

Epidemiol Infect

authors

Yakubu DE,Abadi FJ,Pennington TH

doi

10.1017/s0950268800051463

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

53-65

issue

1

eissn

0950-2688

issn

1469-4409

journal_volume

113

pub_type

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