Abstract:
:The purpose of this study was to develop a method for identifying newly diagnosed tuberculosis (TB) patients at risk for TB adverse events in Tamaulipas, Mexico. Surveillance data between 2006 and 2013 (8431 subjects) was used to develop risk scores based on predictive modelling. The final models revealed that TB patients failing their treatment regimen were more likely to have at most a primary school education, multi-drug resistance (MDR)-TB, and few to moderate bacilli on acid-fast bacilli smear. TB patients who died were more likely to be older males with MDR-TB, HIV, malnutrition, and reporting excessive alcohol use. Modified risk scores were developed with strong predictability for treatment failure and death (c-statistic 0·65 and 0·70, respectively), and moderate predictability for drug resistance (c-statistic 0·57). Among TB patients with diabetes, risk scores showed moderate predictability for death (c-statistic 0·68). Our findings suggest that in the clinical setting, the use of our risk scores for TB treatment failure or death will help identify these individuals for tailored management to prevent these adverse events. In contrast, the available variables in the TB surveillance dataset are not robust predictors of drug resistance, indicating the need for prompt testing at time of diagnosis.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Abdelbary BE,Garcia-Viveros M,Ramirez-Oropesa H,Rahbar MH,Restrepo BIdoi
10.1017/S0950268817001911subject
Has Abstractpub_date
2017-10-01 00:00:00pages
3020-3034issue
14eissn
0950-2688issn
1469-4409pii
S0950268817001911journal_volume
145pub_type
杂志文章abstract::We analysed a cross-sectional telephone survey of U.S. adults to assess the impact of selected characteristics on healthcare-seeking behaviours and treatment practices of people with influenza-like illness (ILI) from September 2009 to March 2010. Of 216,431 respondents, 8.1% reported ILI. After adjusting for selected ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813000654
更新日期:2014-01-01 00:00:00
abstract::An outbreak of legionellosis associated with a hotel in Sydney, Australia, and the subsequent epidemiological and environmental investigations are described. Four cases of Legionnaires' disease were notified to the Public Health Unit. A cross-sectional study of 184 people who attended a seminar at the hotel was carrie...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800052420
更新日期:1996-04-01 00:00:00
abstract::Annual overviews of waterborne disease outbreaks associated with untreated recreational water use provided by authorities responsible for bathing-water quality and public health in The Netherlands revealed 742 outbreaks during 1991-2007 mainly comprising of skin conditions (48%) and gastroenteritis (31%) and involving...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810002347
更新日期:2011-07-01 00:00:00
abstract::A mu-capture enzyme-linked immunosorbent assay (ELISA) for detecting chlamydia-specific IgM was developed by use of the heat stable, lipopolysaccharide group-specific antigen and an alkaline phosphatase-labelled anti-chlamydia group-specific monoclonal antibody conjugate. The test was used to study the serological res...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800054339
更新日期:1988-10-01 00:00:00
abstract::Influenza and respiratory syncytial virus (RSV) are similarly structured viruses with similar environmental survival, but different routes of transmission. While RSV is transmitted predominantly by direct and indirect contact, influenza is also transmitted by aerosol. The cold, dry conditions of temperate winters appe...
journal_title:Epidemiology and infection
pub_type: 杂志文章,评审
doi:10.1017/S0950268814002702
更新日期:2015-04-01 00:00:00
abstract::Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) with the type IV staphylococcal chromosomal cassette mec (SCCmec) is rarely reported as being acquired in hospital. We report a hospital outbreak, in Grampian, Scotland, of eight cases of skin and soft-tissue infections due to such a strain. Al...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809002234
更新日期:2009-09-01 00:00:00
abstract::Nosocomial infection or colonization due to enterococci with high-level resistance to vancomycin (minimal inhibitory concentrations [MICs] between 64 and greater than 2000 mg/L) has occurred in 41 patients with renal disease. These vancomycin-resistant enterococci were cultured from many sources including blood. All b...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800030478
更新日期:1989-08-01 00:00:00
abstract::Demographic and epidemiological field data were used in a deterministic model to describe dog rabies transmission in Machakos District, Kenya and to predict the impact of potential vaccination strategies for its control. The basic reproduction number (R0) was estimated to be 2.44 (1.52-3.36, 95% confidence limits). Th...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268802006957
更新日期:2002-08-01 00:00:00
abstract::Healthcare workers (HCWs) reporting no history of varicella frequently receive varicella vaccination (vOka) if they test varicella-zoster virus (VZV) immunoglobulin G (IgG) negative. In this study, the utilities of VZV-IgG time-resolved fluorescence immunoassay (VZV-TRFIA) and a commercial VZV-IgG purified glycoprotei...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816000595
更新日期:2016-08-01 00:00:00
abstract::Eight strains of influenza C virus isolated in various areas of Japan between January 1985 and January 1989 were compared using monoclonal antibodies to the haemagglutinin-esterase (HE) glycoproteins and by oligonucleotide mapping of total vRNA. Five of six strains isolated during 1986-9 were closely related to one an...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800049827
更新日期:1992-04-01 00:00:00
abstract::Multiple cases of atypical scrapie in the same holding and co-existence with classical scrapie have been reported in Great Britain. A two-stage simulation tool was developed by combining a sampling algorithm and a hierarchical Bayesian model to simulate the number of positive cases of atypical scrapie from: (i) random...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816000303
更新日期:2016-07-01 00:00:00
abstract::Mycobacterium avium subspecies paratuberculosis (Map), the cause of ruminant paratuberculosis, has been proposed as the causative agent of Crohn's disease. The objective of this study was to determine whether exposure to clinical cases of bovine paratuberculosis was a risk factor for Crohn's disease. A questionnaire w...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805004681
更新日期:2006-02-01 00:00:00
abstract::This longitudinal field study investigated the hypothesis that persistently high antibody levels indicate a high risk of Salmonella Dublin shedding in animals in 14 endemically infected dairy herds. A hierarchical multivariable logistic regression was used to analyse 6614 paired faecal cultures and four types of tempo...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812002579
更新日期:2013-09-01 00:00:00
abstract::Clinical information was collected on 722 cases of Listeria monocytogenes infections in humans occurring in Britain between 1967 and 1985. This series comprised 34% (248 cases) associated with pregnancy and 66% (474 cases) in non-pregnant adults and juveniles. The cases not associated with pregnancy comprised: 76% in ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800059355
更新日期:1990-04-01 00:00:00
abstract::The sequence of 165 nucleotides at the 3' end of the 1D (VP1) gene of foot-and-mouth disease (FMD) virus was determined for 44 type Asia 1 strains isolated from throughout Asia between 1954-92. Analysis of the relationships between the virus genomes showed epidemiological links not previously evident. The possible ori...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800057587
更新日期:1994-02-01 00:00:00
abstract::Vitamin D has been shown to be an important immune system regulator. Vitamin D insufficiency during winter may cause increased susceptibility to upper respiratory tract infections (URIs). To determine whether vitamin D supplementation during the winter season prevents or decreases URI symptoms, 162 adults were randomi...
journal_title:Epidemiology and infection
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0950268809002404
更新日期:2009-10-01 00:00:00
abstract::We investigated the first laboratory-confirmed human case of cowpox virus infection in Russia since 1991. Phylogenetic studies of haemagglutinin, TNF-α receptor-like protein and thymidine kinase regions showed significant differences with known orthopoxviruses, including unique amino-acid substitutions and deletions. ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268816002922
更新日期:2017-03-01 00:00:00
abstract::In 1993 New York and Texas each reported a human rabies case traced to a rare variant of rabies virus found in an uncommon species of bat. This study examined the epidemiology of bat rabies in New York State. Demographic, species, and animal-contact information for bats submitted for rabies testing from 1988-92 was an...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800068515
更新日期:1994-12-01 00:00:00
abstract::Historically, Shigella sonnei has dominated other Shigella species infection in men who have sex with men (MSM) in Montréal. In early 2010, Toronto reported increased proportions of the more pathogenic S. flexneri, HIV co-infection and MSM in shigellosis cases since 2009. Analytical methods were used to assess whether...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268812000738
更新日期:2012-11-01 00:00:00
abstract::The objective of this study was to model the age-time-dependent incidence of hepatitis B while estimating the impact of vaccination. While stochastic models/time-series have been used before to model hepatitis B cases in the absence of knowledge on the number of susceptibles, this paper proposed using a method that fi...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268807008692
更新日期:2008-03-01 00:00:00
abstract::West Nile virus (WNV) is now endemic in the USA. After the widespread surge of virus activity across the USA, research has flourished, and our knowledge base has significantly expanded over the past 10 years since WNV was first recognized in New York City. This article provides a review of the virology of WNV, history...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268811000185
更新日期:2011-06-01 00:00:00
abstract::The epidemiological data on shigellosis in Teknaf, a coastal area of Bangladesh, were reviewed for a 10-year period (1975-84). Certain similarities and differences were observed in the epidemiology of the disease in Teknaf when compared with urban Dhaka and rural Matlab. Similarities included: round-the-year infection...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800047622
更新日期:1990-08-01 00:00:00
abstract::Mosquito-borne Sindbis virus (SINV) causes rash-arthritis syndrome in Finland. Major outbreaks with approximately 7-year cycles have caused substantial burden of illness. Forest dwelling grouse are suspected to be amplifying hosts, with the infection transmitted to humans by mosquito bites. SINV infection surveillance...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S095026881200249X
更新日期:2013-09-01 00:00:00
abstract::SUMMARYA prospective cohort study with a 1-year telephone follow-up was performed to estimate the incidence of surgical-site infections (SSIs) in hip and knee prostheses. Twenty-five public hospitals equipped with orthopaedic units in two Italian regions were involved. An 8-month surveillance period was set to obtain ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268810001627
更新日期:2011-05-01 00:00:00
abstract::Orf of the hand is an uncommon zoonotic infection caused by a dermotropic DNA virus that belongs to the Parapoxvirus genus of the family Poxviridae. It is transmitted to humans through contact with infected sheep and goats and is reported as an occupational disease. We report nine cases of human orf seen in the hands ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268805003778
更新日期:2005-08-01 00:00:00
abstract::Fourteen people living in or near the city of Gloucester fell ill with Legionnaires' disease caused by Legionella pneumophila serogroup (SG) 1 between 27 August and 27 October 1986. Another patient had fallen ill on 30 May. Nine of the 15 were diagnosed retrospectively during a case finding exercise. There were three ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/s0950268800048767
更新日期:1991-08-01 00:00:00
abstract::Hypothalamic-pituitary-adrenocortical (HPA) regulation in adults is influenced by early psychosocial adversity, but the role of infectious disease history is poorly understood. We studied the association between cumulative pathogen burden and cortisol profile over the day in a sample of 317 healthy men and women aged ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268809002738
更新日期:2009-12-01 00:00:00
abstract::IgM- and IgG-capture ELISAs are widely used as diagnostic tests for confirmation of dengue virus infection. The positive rate of anti-dengue IgM and IgG detection was examined in primary and secondary dengue virus infections in the setting of a provincial hospital using IgM- and IgG-capture ELISAs. Disease day 1 was d...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268805005753
更新日期:2006-08-01 00:00:00
abstract::In this study we collected and analysed data of the severe burn patients at our institution over an 11-year period in order to shed light on the controversial role of bloodstream infection (BSI) as a predictive factor for mortality in this burn population. The factors examined were age, total body surface area, smoke ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268813002501
更新日期:2014-10-01 00:00:00
abstract::This study aimed to reveal the associated risk factors for latent tuberculosis infection (LTBI) detected by T-SPOT.TB assay among health care workers (HCWs) at different working locations or job categories in China. This cross-sectional study included 934 HCWs who underwent the T-SPOT.TB assay. Demographic and social ...
journal_title:Epidemiology and infection
pub_type: 杂志文章
doi:10.1017/S0950268818002777
更新日期:2019-01-01 00:00:00