Abstract:
:To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed influenza in adult ICUs in a network of Canadian hospitals between 2006 and 2012. There were 626 influenza-positive patients admitted to ICUs over the six influenza seasons, representing 17·9% of hospitalized influenza patients, 3·1/10,000 hospital admissions. Variability occurred in admission rate and proportion of hospital influenza patients who were admitted to ICUs (proportion range by year: 11·7-29·4%; 21·3% in the 2009-2010 pandemic). In logistic regression models ICU patients were younger during the pandemic and post-pandemic period, and more likely to be obese than hospital non-ICU patients. Influenza B accounted for 14·2% of all ICU cases and had a similar ICU admission rate as influenza A. Influenza-related mortality was 17·8% in ICU patients compared to 2·0% in non-ICU patients.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Taylor G,Abdesselam K,Pelude L,Fernandes R,Mitchell R,McGeer A,Frenette C,Suh KN,Wong A,Katz K,Wilkinson K,Mersereau T,Gravel D,Canadian Nosocomial Infection Surveillance Program (CNISP).doi
10.1017/S0950268815002113subject
Has Abstractpub_date
2016-03-01 00:00:00pages
741-50issue
4eissn
0950-2688issn
1469-4409pii
S0950268815002113journal_volume
144pub_type
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