Abstract:
:Equine influenza virus (EIV) causes a highly contagious respiratory disease in equids, with confirmed outbreaks in Europe, America, North Africa, and Asia. Although China, Mongolia, and Japan have reported equine influenza outbreaks, Korea has not. Since 2011, we have conducted a routine surveillance programme to detect EIV at domestic stud farms, and isolated H3N8 EIV from horses showing respiratory disease symptoms. Here, we characterized the genetic and biological properties of this novel Korean H3N8 EIV isolate. This H3N8 EIV isolate belongs to the Florida sublineage clade 1 of the American H3N8 EIV lineage, and surprisingly, possessed a non-structural protein (NS) gene segment, where 23 bases of the NS1-encoding region were naturally truncated. Our preliminary biological data indicated that this truncation did not affect virus replication; its effect on biological and immunological properties of the virus will require further study.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Na W,Kang B,Kim HI,Hong M,Park SJ,Jeoung HY,An DJ,Moon H,Kim JK,Song Ddoi
10.1017/S095026881300143Xsubject
Has Abstractpub_date
2014-04-01 00:00:00pages
759-66issue
4eissn
0950-2688issn
1469-4409pii
S095026881300143Xjournal_volume
142pub_type
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