Developing a risk management framework to improve public health outcomes by enumerating Salmonella in ground turkey.

Abstract:

:Salmonella spp. continue to be a leading cause of foodborne morbidity worldwide. To assess the risk of foodborne disease, current national regulatory schemes focus on prevalence estimates of Salmonella and other pathogens. The role of pathogen quantification as a risk management measure and its impact on public health is not well understood. To address this information gap, a quantitative risk assessment model was developed to evaluate the impact of pathogen enumeration strategies on public health after consumption of contaminated ground turkey in the USA. Public health impact was evaluated by using several dose-response models for high- and low-virulent strains to account for potential under- or overestimation of human health impacts. The model predicted 2705-21 099 illnesses that would result in 93-727 reported cases of salmonellosis. Sensitivity analysis predicted cooking an unthawed product at home as the riskiest consumption scenario and microbial concentration the most influential input on the incidence of human illnesses. Model results indicated that removing ground turkey lots exceeding contamination levels of 1 MPN/g and 1 MPN in 25 g would decrease the median number of illnesses by 86-94% and 99%, respectively. For a single production lot, contamination levels higher than 1 MPN/g would be needed to result in a reported case to public health officials. At contamination levels of 10 MPN/g, there would be a 13% chance of detecting an outbreak, and at 100 MPN/g, the likelihood of detecting an outbreak increases to 41%. Based on these model prediction results, risk management strategies should incorporate pathogen enumeration. This would have a direct impact on illness incidence linking public health outcomes with measurable food safety objectives.

journal_name

Epidemiol Infect

authors

Sampedro F,Wells SJ,Bender JB,Hedberg CW

doi

10.1017/S095026881800328X

subject

Has Abstract

pub_date

2018-12-06 00:00:00

pages

1-8

eissn

0950-2688

issn

1469-4409

pii

S095026881800328X

pub_type

杂志文章
  • Bloodstream infection as a predictor for mortality in severe burn patients: an 11-year study.

    abstract::In this study we collected and analysed data of the severe burn patients at our institution over an 11-year period in order to shed light on the controversial role of bloodstream infection (BSI) as a predictive factor for mortality in this burn population. The factors examined were age, total body surface area, smoke ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813002501

    authors: Egozi D,Hussein K,Filson S,Mashiach T,Ullmann Y,Raz-Pasteur A

    更新日期:2014-10-01 00:00:00

  • Description of two waterborne disease outbreaks in France: a comparative study with data from cohort studies and from health administrative databases.

    abstract::Waterborne disease outbreaks (WBDO) of acute gastrointestinal illness (AGI) are a public health concern in France. Their occurrence is probably underestimated due to the lack of a specific surveillance system. The French health insurance database provides an interesting opportunity to improve the detection of these ev...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815001673

    authors: Mouly D,Van Cauteren D,Vincent N,Vaissiere E,Beaudeau P,Ducrot C,Gallay A

    更新日期:2016-02-01 00:00:00

  • Seroprevalence, correlates and trends of Helicobacter pylori infection in the Israeli population.

    abstract::We examined the prevalence, correlates and trends of H. pylori infection in Israel using residual sera obtained in 2007-2008 from 1466 Jewish subjects aged 0-77 years and 897 Arabs aged 0-19 years, and in 2000-2001 from 627 Jewish and 575 Arab subjects aged 0-19 years. H. pylori IgG antibodies were measured by ELISA. ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811002081

    authors: Muhsen K,Cohen D,Spungin-Bialik A,Shohat T

    更新日期:2012-07-01 00:00:00

  • Vaccine prophylaxis of abattoir-associated Q fever: eight years' experience in Australian abattoirs.

    abstract::During the period 1981-8 a clinical trial of a Q fever vaccine (Q-vax; Commonwealth Serum Laboratories, Melbourne) has been conducted in abattoir workers and other at-risk groups in South Australia. Volunteers in four abattoirs and visitors to the abattoirs were given one subcutaneous dose of 30 micrograms of a formal...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800059458

    authors: Marmion BP,Ormsbee RA,Kyrkou M,Wright J,Worswick DA,Izzo AA,Esterman A,Feery B,Shapiro RA

    更新日期:1990-04-01 00:00:00

  • Dengue, chikungunya and zika virus coinfection: results of the national surveillance during the zika epidemic in Colombia.

    abstract::Our objective was to determine the frequency of zika (ZIKV), chikungunya (CHIKV) and dengue (DENV) virus coinfection and describe the mortality cases that occurred during the epidemiologic surveillance of the ZIKV epidemic in Colombia. We analysed all cases of suspected ZIKV infection that were reported to the Nationa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881800359X

    authors: Mercado-Reyes M,Acosta-Reyes J,Navarro-Lechuga E,Corchuelo S,Rico A,Parra E,Tolosa N,Pardo L,González M,Martìn-Rodriguez-Hernández J,Karime-Osorio L,Ospina-Martinez M,Rodriguez-Perea H,Del Rio-Pertuz G,Viasus D

    更新日期:2019-01-01 00:00:00

  • Epidemiological features of Mediterranean spotted fever, murine typhus, and Q fever in Split-Dalmatia County (Croatia), 1982-2002.

    abstract::We determined the epidemiological features of three zoonoses in hospitalized patients in southern Croatia. Patients were diagnosed by serological testing. Clinical and epidemiological data were also collected. Between 1982 and 2002, Mediterranean spotted fever (MSF) was diagnosed in 126 (incidence rate 1.27/100,000 pe...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009491

    authors: Punda-Polić V,Luksić B,Capkun V

    更新日期:2008-07-01 00:00:00

  • Predicting treatment failure, death and drug resistance using a computed risk score among newly diagnosed TB patients in Tamaulipas, Mexico.

    abstract::The purpose of this study was to develop a method for identifying newly diagnosed tuberculosis (TB) patients at risk for TB adverse events in Tamaulipas, Mexico. Surveillance data between 2006 and 2013 (8431 subjects) was used to develop risk scores based on predictive modelling. The final models revealed that TB pati...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268817001911

    authors: Abdelbary BE,Garcia-Viveros M,Ramirez-Oropesa H,Rahbar MH,Restrepo BI

    更新日期:2017-10-01 00:00:00

  • Characteristics and TB treatment outcomes in TB patients with viral hepatitis, New York City, 2000-2010.

    abstract::Literature surrounding the burden of and factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in persons with tuberculosis (TB) disease remains limited and focused on populations outside the USA. Cross-matched New York City (NYC) TB and viral hepatitis surveillance data were used to es...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814002970

    authors: Bushnell G,Stennis NL,Drobnik AM,Proops DC,Ahuja SD,Bornschlegel K,Fuld J

    更新日期:2015-07-01 00:00:00

  • Outbreak of Listeria monocytogenes infections linked to a pasteurized ice cream product served to hospitalized patients.

    abstract::Two cases of hospital-acquired listeriosis were linked to a commercially produced, pasteurized ice cream mix. Manufacturers should implement safety measures from the Food Safety Modernization Act to minimize the risk of Listeria contamination. Dietary guidelines for persons at high risk of listeriosis may need revisio...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815003039

    authors: Rietberg K,Lloyd J,Melius B,Wyman P,Treadwell R,Olson G,Kang MG,Duchin JS

    更新日期:2016-10-01 00:00:00

  • Cryptosporidium hominis genotypes involved in increased incidence and clusters of cases, Navarra, Spain, 2012.

    abstract::SUMMARY Two clusters of confirmed cryptosporidiosis infections were detected in Navarra, Spain, in the summer of 2012, in the context of an increased incidence in the region. Molecular subtyping of Cryptosporidium hominis determined that one cluster, occurring in an urban area, was due to the predominant circulating s...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268814001836

    authors: Fuentes I,Martín C,Beristain X,Mazón A,Saugar JM,Blanco A,García Cenoz M,Valle-Cristia M,Ezpeleta C,Castilla J

    更新日期:2015-04-01 00:00:00

  • Salmonellosis associated with mass catering: a survey of European Union cases over a 15-year period.

    abstract::Salmonella spp. is the causative agent of a foodborne disease called salmonellosis, which is the second most commonly reported gastrointestinal infection in the European Union (EU). Although over the years the annual number of cases of foodborne salmonellosis within the EU has decreased markedly, in 2014, a total of 8...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268816001540

    authors: Osimani A,Aquilanti L,Clementi F

    更新日期:2016-10-01 00:00:00

  • Determination of cut-off cycle threshold values in routine RT-PCR assays to assist differential diagnosis of norovirus in children hospitalized for acute gastroenteritis.

    abstract::Norovirus (NV) is an important cause of acute gastroenteritis in children, but is also frequently detected in asymptomatic children, which complicates the interpretation of NV detection results in both the clinical setting and population prevalence studies. A total of 807 faecal samples from children aged <5 years hos...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881500059X

    authors: Trang NV,Choisy M,Nakagomi T,Chinh NT,Doan YH,Yamashiro T,Bryant JE,Nakagomi O,Anh DD

    更新日期:2015-11-01 00:00:00

  • Changes in antibiotic usage and susceptibility in nosocomial Enterobacteriaceae and Pseudomonas isolates following the introduction of ertapenem to hospital formulary.

    abstract::There is concern that widespread usage of ertapenem may promote cross-resistance to other carbapenems. To analyse the impact that adding ertapenem to our hospital formulary had on usage of other broad-spectrum agents and on susceptibilities of nosocomial Enterobacteriaceae and Pseudomonas isolates, we performed interr...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811000082

    authors: Graber CJ,Hutchings C,Dong F,Lee W,Chung JK,Tran T

    更新日期:2012-01-01 00:00:00

  • Length of stay an important mediator of hospital-acquired methicillin-resistant Staphylococcus aureus.

    abstract::Hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) is becoming increasingly established in Asian hospitals. The primary aim of this study was to decompose the risk factors for HA-MRSA based on conceptual clinical pathways. The secondary aim was to show the amount of effect attributable to antibiot...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268815002733

    authors: Wong JG,Chen MI,Win MK,Ng PY,Chow A

    更新日期:2016-04-01 00:00:00

  • Incomplete sanitation of a meat grinder and ingestion of raw ground beef: contributing factors to a large outbreak of Salmonella typhimurium infection.

    abstract::Consumers in the United States continue to eat raw or undercooked foods of animal origin despite public health warnings following several well-publicized outbreaks. We investigated an outbreak of Salmonella serotype Typhimurium infection in 158 patients in Wisconsin during the 1994 Christmas holiday period. To determi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268897007851

    authors: Roels TH,Frazak PA,Kazmierczak JJ,Mackenzie WR,Proctor ME,Kurzynski TA,Davis JP

    更新日期:1997-10-01 00:00:00

  • Risk factors for ciprofloxacin resistance in reported Campylobacter infections in southern Alberta.

    abstract::We conducted a case-control study examining risk factors for ciprofloxacin resistance in Campylobacter infections that were reported in 2004 and 2005 in two health regions in southern Alberta. The study questionnaire included questions about recent travel and antibiotic use, food consumption frequency, use of househol...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807009296

    authors: Johnson JY,McMullen LM,Hasselback P,Louie M,Jhangri G,Saunders LD

    更新日期:2008-07-01 00:00:00

  • Secular trends in the epidemiology of shingles in Alberta.

    abstract::Varicella vaccine was licensed in Canada in 1998, and a publicly funded vaccination programme introduced in the province of Alberta in 2001. In theory the vaccination programme might increase the burden of disease from shingles, making it important to develop baseline data against which future comparisons can be made....

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268807007893

    authors: Russell ML,Schopflocher DP,Svenson L,Virani SN

    更新日期:2007-08-01 00:00:00

  • Psittacosis outbreak after participation in a bird fair, Western France, December 2008.

    abstract::In December 2008, three hospitalized cases of suspected psittacosis infection were notified by respiratory disease clinicians from a local hospital to the Regional Epidemiology Unit of Pays de la Loire, France. They all had attended a bird fair. A retrospective cohort study was conducted among exhibitors and organizer...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268811000409

    authors: Belchior E,Barataud D,Ollivier R,Capek I,Laroucau K,de Barbeyrac B,Hubert B

    更新日期:2011-10-01 00:00:00

  • An appraisal of methods used in the examination of retail samples of cows milk.

    abstract::The use of the methylene blue test for the examination of cows milk was investigated in an inter-laboratory survey. A poor relationship was found between results of these tests and total viable counts. Coliforms were detected in a large number of pasteurized milks, indicating frequent post-pasteurization contamination...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800067121

    authors: Greenwood MH,Gill P,Coetzee EF,Ford BM,Hooper WL,Matthews SC,Patrick S

    更新日期:1988-06-01 00:00:00

  • HIV incidence rates among drug users in northern Thailand, 1993-7.

    abstract::Drug use is a major mode of HIV transmission in Thailand. This study determined HIV incidence rates among drug users in a regional drug treatment centre in northern Thailand. A retrospective cohort of repeatedly-hospitalized drug users between 1993 and 1997 was formed and HIV incidence rates were calculated. The overa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268899004197

    authors: Jittiwutikarn J,Sawanpanyalert P,Rangsiveroj N,Satitvipawee P

    更新日期:2000-08-01 00:00:00

  • A Middle East subregional laboratory-based surveillance network on foodborne diseases established by Jordan, Israel, and the Palestinian Authority.

    abstract::In late 2002, health professionals from the ministries of health and academia of Jordan, the Palestinian Authority and Israel formed the Middle East Consortium on Infectious Disease Surveillance (MECIDS) to facilitate trans-border cooperation in response to infectious disease outbreaks. The first mission of MECIDS was...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268810000270

    authors: Cohen D,Gargouri N,Ramlawi A,Abdeen Z,Belbesi A,Al Hijawi B,Haddadin A,Sheikh Ali S,Al Shuaibi N,Bassal R,Yishai R,Green MS,Leventhal A

    更新日期:2010-10-01 00:00:00

  • Poliomyelitis: eradication in sight.

    abstract::Eradication of poliomyelitis most likely will occur. In fact, it is almost gone from the Western Hemisphere. Health workers in Sweden, Finland, and the Netherlands routinely vaccinate almost all children with the inactivated poliovaccines (IPV). Despite good vaccination coverage, polio can still occur. For example...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/s0950268800049451

    authors: Melnick JL

    更新日期:1992-02-01 00:00:00

  • Risk factors for hospital-acquired methicillin-resistant Staphylococcus aureus bacteraemia: a case-control study.

    abstract::A case-control study was undertaken in an acute district general hospital to identify risk factors for hospital-acquired bacteraemia caused by methicillin-resistant Staphylococcus aureus (MRSA). Cases of hospital-acquired MRSA bacteraemia were defined as consecutive patients from whom MRSA was isolated from a blood sa...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0950268806006327

    authors: Carnicer-Pont D,Bailey KA,Mason BW,Walker AM,Evans MR,Salmon RL

    更新日期:2006-12-01 00:00:00

  • Study of colonization resistance for Enterobacteriaceae in man by experimental contamination and biotyping as well as the possible role of antibodies in the clearance of these bacteria from the intestines.

    abstract::The colonization resistance (CR) of the digestive tract was determined in 10 healthy volunteers by oral contamination with a neomycin resistant Escherichia coli (NR-E. coli) strain and measurement of the faecal concentration of this strain during 14 days after the contamination. This 'gold standard' was compared with ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268800049311

    authors: Apperloo-Renkema HZ,van der Waaij D

    更新日期:1991-12-01 00:00:00

  • A 10-year cohort analysis of routine paediatric ART data in a rural South African setting.

    abstract::South Africa's paediatric antiretroviral therapy (ART) programme is managed using a monitoring and evaluation tool known as TIER.Net. This electronic system has several advantages over paper-based systems, allowing profiling of the paediatric ART programme over time. We analysed anonymized TIER.Net data for HIV-infect...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268816001916

    authors: Lilian RR,Mutasa B,Railton J,Mongwe W,McINTYRE JA,Struthers HE,Peters RP

    更新日期:2017-01-01 00:00:00

  • Lessons from 40 years' surveillance of influenza in England and Wales.

    abstract::The influenza virus continues to pose a significant threat to public health throughout the world. Current avian influenza outbreaks in humans have heightened the need for improved surveillance and planning. Despite recent advances in the development of vaccines and antiviral drugs, seasonal epidemics of influenza cont...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章,评审

    doi:10.1017/S0950268807009910

    authors: Fleming DM,Elliot AJ

    更新日期:2008-07-01 00:00:00

  • The changing epidemiological pattern of hepatitis A in England and Wales.

    abstract::Sera from an age-stratified sample of 4188 individuals, submitted for diagnostic purposes to 15 public health laboratories in England and Wales in 1996, were tested for hepatitis A antibody. The serological profiles were consistent with declining incidence in the past. This hypothesis was tested by comparing the serol...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s095026880200701x

    authors: Morris MC,Gay NJ,Hesketh LM,Morgan-Capner P,Miller E

    更新日期:2002-06-01 00:00:00

  • New world origins for haemoparasites infecting United Kingdom grey squirrels (Sciurus carolinensis), as revealed by phylogenetic analysis of bartonella infecting squirrel populations in England and the United States.

    abstract::Phylogenetic analyses of bartonella have suggested divergence between bartonellae that infect mammals native to the Old and New Worlds. We characterized bartonella isolated from Eastern grey squirrels (Sciurius carolinensis) in the United States and from grey and red squirrels (Sciurus vulgaris) in the United Kingdom ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/s0950268802007768

    authors: Bown KJ,Ellis BA,Birtles RJ,Durden LA,Lello J,Begon M,Bennett M

    更新日期:2002-12-01 00:00:00

  • Measuring the effect of influenza A(H1N1)pdm09: the epidemiological experience in the West Midlands, England during the 'containment' phase.

    abstract::The West Midlands was the first English region to report sustained community transmission during the 'containment' phase of the influenza A(H1N1)pdm09 pandemic in England. To describe the epidemiological experience in the region, West Midlands and national datasets containing laboratory-confirmed A(H1N1)pdm09 virus ca...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S0950268813001234

    authors: Inglis NJ,Bagnall H,Janmohamed K,Suleman S,Awofisayo A,De Souza V,Smit E,Pebody R,Mohamed H,Ibbotson S,Smith GE,House T,Olowokure B

    更新日期:2014-02-01 00:00:00

  • Isolation and genetic characterization of naturally NS-truncated H3N8 equine influenza virus in South Korea.

    abstract::Equine influenza virus (EIV) causes a highly contagious respiratory disease in equids, with confirmed outbreaks in Europe, America, North Africa, and Asia. Although China, Mongolia, and Japan have reported equine influenza outbreaks, Korea has not. Since 2011, we have conducted a routine surveillance programme to dete...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章

    doi:10.1017/S095026881300143X

    authors: Na W,Kang B,Kim HI,Hong M,Park SJ,Jeoung HY,An DJ,Moon H,Kim JK,Song D

    更新日期:2014-04-01 00:00:00