Assessment of areas at increased risk for poliovirus circulation in Ecuador.

Abstract:

:To assess areas at risk for poliovirus circulation in Ecuador, we first selected provinces at highest risk based on low immunization coverage with three doses of oral poliovirus vaccine, and a low number of reported cases of acute flaccid paralysis (AFP). Subsequently, we reviewed discharge data for the period 1996--2000 for diagnoses compatible with AFP in the only two national referral hospitals in Quito, and at least two main hospitals in each of the six selected provinces. Environmental samples from one or two cities/towns in each selected province were tested for poliovirus. Of the 14 identified AFP-compatible cases, 8 (57%) had been previously reported and investigated. We visited four out of the six unreported cases; none of those four had sequelae compatible with poliomyelitis. From the 14 environmental samples taken, we identified Sabin viruses in six of the samples; no vaccine-derived polioviruses were isolated. Using this methodology, we found no evidence of undetected poliovirus circulation in Ecuador.

journal_name

Epidemiol Infect

authors

Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

doi

10.1017/s0950268804002626

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

787-95

issue

5

eissn

0950-2688

issn

1469-4409

journal_volume

132

pub_type

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