Abstract:
:We conducted a case-control study examining risk factors for ciprofloxacin resistance in Campylobacter infections that were reported in 2004 and 2005 in two health regions in southern Alberta. The study questionnaire included questions about recent travel and antibiotic use, food consumption frequency, use of household and personal hygiene products with antibacterial agents, contact with animals, and potential misuse of antibiotics. Of the 210 patients who participated, 31.0% had ciprofloxacin-resistant Campylobacter infections. Foreign travel was the strongest predictor of resistance. Surprisingly, possession of antibiotics for future use was identified as a risk factor for resistance. We also examined the potential for participation bias and resistance misclassification to affect the resulting multivariable models. Participation bias appears to have had a substantial effect on the model results, but the estimated misclassification effect due to the use of different ciprofloxacin susceptibility testing methods was only slight.
journal_name
Epidemiol Infectjournal_title
Epidemiology and infectionauthors
Johnson JY,McMullen LM,Hasselback P,Louie M,Jhangri G,Saunders LDdoi
10.1017/S0950268807009296subject
Has Abstractpub_date
2008-07-01 00:00:00pages
903-12issue
7eissn
0950-2688issn
1469-4409pii
S0950268807009296journal_volume
136pub_type
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