Risk factors for ciprofloxacin resistance in reported Campylobacter infections in southern Alberta.

Abstract:

:We conducted a case-control study examining risk factors for ciprofloxacin resistance in Campylobacter infections that were reported in 2004 and 2005 in two health regions in southern Alberta. The study questionnaire included questions about recent travel and antibiotic use, food consumption frequency, use of household and personal hygiene products with antibacterial agents, contact with animals, and potential misuse of antibiotics. Of the 210 patients who participated, 31.0% had ciprofloxacin-resistant Campylobacter infections. Foreign travel was the strongest predictor of resistance. Surprisingly, possession of antibiotics for future use was identified as a risk factor for resistance. We also examined the potential for participation bias and resistance misclassification to affect the resulting multivariable models. Participation bias appears to have had a substantial effect on the model results, but the estimated misclassification effect due to the use of different ciprofloxacin susceptibility testing methods was only slight.

journal_name

Epidemiol Infect

authors

Johnson JY,McMullen LM,Hasselback P,Louie M,Jhangri G,Saunders LD

doi

10.1017/S0950268807009296

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

903-12

issue

7

eissn

0950-2688

issn

1469-4409

pii

S0950268807009296

journal_volume

136

pub_type

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